Cruises: 3495

Santiago De Cuba, Cuba Luxury Cruises

Considered the cultural capital of Cuba, Santiago is a lively, passionate destination steeped in breath-taking architecture and history. One of its most impressive sights is the Castillo de San Pedro de la Roca del Morro. This stunning fort sits high over the harbour, and was originally designed to defend the city from pirates. The lengthy time to complete its construction rendered this unnecessary, and it was instead used as a prison for many years before its recent conversion to a museum. The views from the fort across the bay are spectacular.

The Moncada Barracks are another renowned landmark, the sight of one of history’s biggest failed putsches or coups. It was stormed by Castro but survived, and was later converted into a museum with intricate artefacts, models of the attack and photographs of those who lost their lives. Beyond the historical sights, Santiago breathes excitement through its incredible bars and restaurants – be sure to sample the memorable atmosphere and the fine cuisine during your visit. And don’t miss the chance to explore the unique boutiques and vendors offering gifts of all kinds.

The currency in Santiago de Cuba is the Cuban Convertible Peso. Santiago de Cuba is 4 hours behind Greenwich Mean Time (GMT -4).

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1 Timeless Cuba
28 September 2019 - 7 nights

Miami | Havana, Cuba | Havana, Cuba | Cienfuegos, Cuba | Santiago De Cuba, Cuba | Miami

Fly Cruise£3599pp
Cruise Only£2899pp
2 Timeless Cuba
05 October 2019 - 7 nights

Miami | Havana, Cuba | Havana, Cuba | Cienfuegos, Cuba | Santiago De Cuba, Cuba | Miami

Fly Cruise£2479pp
Cruise Only£1719pp
3 Cuba in Depth
07 October 2019 - 14 nights

Nassau | Nassau | Long Island | Mayaguana Island | Port Antonio | Santiago De Cuba, Cuba | Santiago De Cuba, Cuba | Casilda | Cienfuegos | Cienfuegos | Maria La Gorda | Havana, Cuba | Havana, Cuba | Arrive UK more

Fly Cruise£8289pp
4 Cuba Charms
30 October 2019 - 10 nights

Miami | Key West | Havana, Cuba | Cienfuegos, Cuba | Cienfuegos, Cuba | Santiago De Cuba, Cuba | Santiago De Cuba, Cuba | Nassau | Miami more

Fly Cruise£3879pp
Cruise Only£3229pp
5 Stars of The Cuban Sky
04 November 2019 - 12 nights

Miami | Havana, Cuba | Havana, Cuba | Antilla (Nipe Bay), Cuba | Santiago De Cuba, Cuba | Santiago De Cuba, Cuba | Port Antonio | West End, Cayman Brac, Cayman Islands | Cienfuegos, Cuba | Cienfuegos, Cuba | Miami more

Fly Cruise£5939pp
Cruise Only£5179pp
6 Stars of the Cuban Sky
16 November 2019 - 12 nights

Miami | Cienfuegos, Cuba | Cienfuegos, Cuba | West End, Cayman Brac, Cayman Islands | Port Antonio | Santiago De Cuba, Cuba | Santiago De Cuba, Cuba | Antilla (Nipe Bay), Cuba | Havana, Cuba | Havana, Cuba | Miami more

Fly Cruise£5779pp
Cruise Only£4989pp
7 Fort Lauderdale round-trip
22 November 2019 - 14 nights

Ft. Lauderdale | Georgetown (Grand Cayman) | Santiago De Cuba | Santiago De Cuba | Cienfuegos, Cuba | Havana (La Habana), Cuba | Havana (La Habana), Cuba | Cozumel | Belize City | Key West | Ft. Lauderdale more

Fly Cruise£5249pp
Cruise Only£5819pp
8 Cuba Intensive Voyage
25 November 2019 - 11 nights

Miami | Santiago De Cuba, Cuba | Santiago De Cuba, Cuba | Cienfuegos, Cuba | Havana, Cuba | Havana, Cuba | Havana, Cuba | Cozumel | Miami more

Fly Cruise£2819pp
Cruise Only£3469pp
9 Cuba Intensive Voyage
06 December 2019 - 13 nights

Miami | Labadee, Haiti | Santiago De Cuba, Cuba | Santiago De Cuba, Cuba | Cienfuegos, Cuba | Cienfuegos, Cuba | Havana, Cuba | Havana, Cuba | Cozumel | Miami more

Fly Cruise£3239pp
Cruise Only£3469pp
10 Stars of Cuba & Caribbean Skies
10 December 2019 - 11 nights

Miami | Havana, Cuba | Havana, Cuba | Punta Frances, Isla De La | Cienfuegos, Cuba | West End, Cayman Brac, Cayman Islands | Port Antonio | Santiago De Cuba, Cuba | Santiago De Cuba, Cuba | Isla Catalina, Dominican Republic | San Juan more

Fly Cruise£4999pp
Cruise Only£4069pp
11 Grand Cuban Holiday
10 December 2019 - 25 nights

Miami | Havana, Cuba | Havana, Cuba | Punta Frances, Isla De La | Cienfuegos, Cuba | West End, Cayman Brac, Cayman Islands | Port Antonio | Santiago De Cuba, Cuba | Santiago De Cuba, Cuba | Isla Catalina, Dominican Republic | San Juan | Gustavia | St. Johns, Antigua And Barbuda | Basseterre | Santo Domingo, Dominican Republic | Port Antonio | Santiago De Cuba, Cuba | Santiago De Cuba, Cuba | Antilla (Nipe Bay), Cuba | Havana, Cuba | Havana, Cuba | Miami more

Fly Cruise£9799pp
Cruise Only£8639pp
12 Cuba Serenade
18 December 2019 - 10 nights

Miami | Havana, Cuba | Havana, Cuba | Cienfuegos, Cuba | Cienfuegos, Cuba | Santiago De Cuba, Cuba | Santiago De Cuba, Cuba | Great Stirrup Cay | Miami more

Fly Cruise£3359pp
Cruise Only£2469pp
13 Holiday Cuban & Caribbean Stars
21 December 2019 - 14 nights

San Juan | Gustavia | St John's, Antigua | Basseterre | Santo Domingo, Dominican Republic | Port Antonio | Santiago De Cuba, Cuba | Santiago De Cuba, Cuba | Antilla (Nipe Bay), Cuba | Havana, Cuba | Havana, Cuba | Miami more

Fly Cruise£8059pp
Cruise Only£6139pp
14 Panama, Central America & Cuba
27 December 2019 - 14 nights

Miami | Key West | Cozumel | Belize City | Roatan | Puerto Limon | Colon | Montego Bay, Jamaica | Santiago De Cuba, Cuba | Miami more

Fly Cruise£5640pp
Cruise OnlyCall
15 Cuba Celebration
28 December 2019 - 11 nights

Miami | Key West | Key West | Key West | Havana, Cuba | Havana, Cuba | Cienfuegos, Cuba | Santiago De Cuba, Cuba | Santiago De Cuba, Cuba | Port Antonio | Great Stirrup Cay | Miami more

Fly Cruise£3249pp
Cruise Only£2469pp
16 Cultural Cuba - Miami to Miami
10 January 2020 - 7 nights

Miami | Miami | Cienfuegos, Cuba | Cienfuegos, Cuba | Cienfuegos, Cuba | Cienfuegos, Cuba | Cienfuegos, Cuba | Cienfuegos, Cuba | Santiago De Cuba, Cuba | Santiago De Cuba, Cuba | Miami | Miami more

Fly Cruise£2590pp
Cruise OnlyCall
17 Cultural Cuba - Miami to Miami
17 January 2020 - 7 nights

Miami | Cienfuegos, Cuba | Cienfuegos, Cuba | Cienfuegos, Cuba | Santiago De Cuba, Cuba | Miami

Fly Cruise£3290pp
Cruise OnlyCall
18 Fort Lauderdale to Fort Lauderdale
23 January 2020 - 11 nights

Ft. Lauderdale | Santiago De Cuba | Santiago De Cuba | Georgetown (Grand Cayman) | Cienfuegos, Cuba | Havana (La Habana), Cuba | Havana (La Habana), Cuba | Bimini | Ft. Lauderdale more

Fly Cruise£4799pp
Cruise OnlyCall
19 Cultural Cuba - Miami to Miami
24 January 2020 - 7 nights

Miami | Miami | Cienfuegos, Cuba | Cienfuegos, Cuba | Cienfuegos, Cuba | Santiago De Cuba, Cuba | Miami more

Fly Cruise£3290pp
Cruise OnlyCall
20 Cultural Cuba - Miami to Miami
31 January 2020 - 7 nights

Miami | Cienfuegos, Cuba | Cienfuegos, Cuba | Cienfuegos, Cuba | Santiago De Cuba, Cuba | Miami

Fly Cruise£3290pp
Cruise OnlyCall
21 Fort Lauderdale,Florida to Fort Lauderdale,Florida
03 February 2020 - 7 nights

Ft. Lauderdale | Santiago De Cuba | Havana (La Habana), Cuba | Havana (La Habana), Cuba | Bimini | Ft. Lauderdale

Fly Cruise£2849pp
Cruise Only£3379pp
22 Cultural Cuba - Miami to Miami
07 February 2020 - 7 nights

Miami | Cienfuegos, Cuba | Cienfuegos, Cuba | Cienfuegos, Cuba | Santiago De Cuba, Cuba | Miami

Fly Cruise£3290pp
Cruise OnlyCall
23 Fort Lauderdale round-trip
10 February 2020 - 7 nights

Ft. Lauderdale | Santiago De Cuba | Santiago De Cuba | Havana (La Habana), Cuba | Havana (La Habana), Cuba | Ft. Lauderdale

Fly Cruise£3249pp
Cruise Only£3739pp
24 Cultural Cuba - Miami to Miami
14 February 2020 - 7 nights

Miami | Cienfuegos, Cuba | Cienfuegos, Cuba | Cienfuegos, Cuba | Santiago De Cuba, Cuba | Miami

Fly Cruise£3290pp
Cruise OnlyCall
25 Fort Lauderdale,Florida to Fort Lauderdale,Florida
17 February 2020 - 7 nights

Ft. Lauderdale | Havana (La Habana), Cuba | Santiago De Cuba | Santiago De Cuba | Bimini | Ft. Lauderdale

Fly Cruise£2899pp
Cruise Only£3379pp
26 Cultural Cuba - Miami to Miami
21 February 2020 - 7 nights

Miami | Cienfuegos, Cuba | Cienfuegos, Cuba | Cienfuegos, Cuba | Santiago De Cuba, Cuba | Miami | Miami more

Fly Cruise£3290pp
Cruise OnlyCall
27 Fort Lauderdale,Florida to Fort Lauderdale,Florida
24 February 2020 - 7 nights

Ft. Lauderdale | Havana (La Habana), Cuba | Havana (La Habana), Cuba | Santiago De Cuba | Bimini | Ft. Lauderdale

Fly Cruise£2899pp
Cruise Only£3379pp
28 Cultural Cuba - Miami to Miami
28 February 2020 - 7 nights

Miami | Miami | Cienfuegos, Cuba | Cienfuegos, Cuba | Cienfuegos, Cuba | Santiago De Cuba, Cuba | Miami more

Fly Cruise£3290pp
Cruise OnlyCall
29 Fort Lauderdale,Florida to Fort Lauderdale,Florida
06 March 2020 - 10 nights

Ft. Lauderdale | Bimini | Key West | Cayman Brac | Santiago De Cuba | Santiago De Cuba | Havana (La Habana), Cuba | Havana (La Habana), Cuba | Ft. Lauderdale more

Fly Cruise£4399pp
Cruise Only£4899pp
30 Fort Lauderdale,Florida to Fort Lauderdale,Florida
16 March 2020 - 7 nights

Ft. Lauderdale | Havana (La Habana), Cuba | Havana (La Habana), Cuba | Santiago De Cuba | Bimini | Ft. Lauderdale

Fly Cruise£2949pp
Cruise Only£3379pp
31 Fort Lauderdale,Florida to Fort Lauderdale,Florida
30 March 2020 - 7 nights

Ft. Lauderdale | Havana (La Habana), Cuba | Havana (La Habana), Cuba | Santiago De Cuba | Bimini | Ft. Lauderdale

Fly Cruise£3199pp
Cruise Only£3379pp
32 Cuba Intensive
10 April 2020 - 11 nights

Miami | Labadee, Haiti | Santiago De Cuba, Cuba | Santiago De Cuba, Cuba | Cienfuegos, Cuba | Isla De La Juventud | Havana, Cuba | Havana, Cuba | Havana, Cuba | Miami more

Fly CruiseCall
Cruise Only£2989pp
33 Cuba Intensive
30 April 2020 - 9 nights

Miami | Key West | Havana, Cuba | Havana, Cuba | Havana, Cuba | Cienfuegos, Cuba | Santiago De Cuba, Cuba | Santiago De Cuba, Cuba | Miami more

Fly Cruise£3699pp
Cruise Only£2279pp
34 Cuba, Panama & the Pacific Holiday
14 December 2020 - 21 nights

Miami | Santiago De Cuba, Cuba | Cienfuegos, Cuba | Cartagena, Colombia | Colon | Corinto | Puerto Quetzal | Cabo San Lucas | San Diego | Los Angeles, California more

Fly Cruise£6790pp
Cruise OnlyCall
35 Viking World Cruise - Miami to London
14 December 2020 - 160 nights

Miami | Santiago De Cuba, Cuba | Cienfuegos, Cuba | Cartagena, Colombia | Colon | Corinto | Puerto Quetzal | Cabo San Lucas | San Diego | Los Angeles, California | Santa Barbara | Kauai (Nawiliwili) | Honolulu | Bora Bora | Moorea | Tahiti, French Polynesia | Bay Of Islands | Auckland | Auckland | Auckland | Napier | Wellington | Christchurch | Hobart, Tasmania | Hobart, Tasmania | Melbourne | Sydney, Australia | Sydney, Australia | Brisbane | Whitsunday Island | Cairns | Thursday Island | Darwin | Komodo | Bali (Benoa) | Semarang (for Borobudur) | Bandar Seri Begawan, Brunei | Kota Kinabalu | Manila | Hong Kong | Hong Kong | Hong Kong | Hue | Saigon (Ho Chi Min City) | Saigon (Ho Chi Min City) | Sihanoukville | Bangkok | Bangkok | Koh Samui, Thailand | Singapore, Singapore | Singapore, Singapore | Kuala Lumpur (Port Klang) | George Town, Malaysia | Colombo | Colombo | Cochin | Goa (Mormugao) | Mumbai | Mumbai | Mumbai | Muscat | Salālah | Aqaba | Luxor (Safaga) | Sharm El Sheikh | Cairo & Giza | Jerusalem (Haifa) | Haifa | Kusadasi, Turkey | Istanbul | Istanbul | Piraeus | Venice | Venice | Split, Croatia | Dubrovnik | Corfu | Naples | Civitavecchia | Livorno | Monte Carlo | Marseille | Barcelona | Barcelona | Murcia, Spain | Granada (Malaga) | Vigo | Portland, UK | Dover | London (Greenwich) | London (Greenwich) more

Fly Cruise£45995pp
Cruise OnlyCall
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