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Amazon River

18th November 2023 FOR 22 NIGHTS | Azamara Quest

Freephone9am - 8pm

0808 202 6105
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This fly cruise holiday is financially protected by AZAMARA CLUB CRUISES under ATOL 10372

Freephone9am - 8pm

0808 202 6105

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EXCLUSIVE OFFER | Top 50 | Includes a FREE upgrade from a Club Balcony Stateroom (B1) to a Club Balcony Plus Stateroom | Includes flights, one-night pre-cruise luxury hotel stay in Barbados and private transfers in Buenos Aires | Book a Club Balcony Stateroom or above and receive $300 FREE to spend on-board per couple, FREE Premium Drinks Package and FREE Wi-Fi for one device

Check you are ready to travel

Please check that you can meet the conditions below in order to travel on this cruise

1) All guests need to be in possession of a valid UK passport. This is also the case on any British Isles cruises. Please click here to check your passport will still be valid on your dates of travel.

2) Please check your travel insurance meets any criteria as specified by your cruise line. You can check your cruise line requirements here. For a travel insurance quote click here. Proof of travel insurance may be required on boarding.

3) Please check the vaccination and testing requirements from the FCDO, your cruise line and any destination countries here


South America offers a spectacular range of sights and experiences on a luxury cruise. You could tour beachfront cities like Rio de Janeiro and get into Brazil’s carnival spirit, or head to secluded tropical ports that act as gateways to the rich jungle wildlife of the Amazon. Learn to tango in Buenos Aires, see the sunset in beautiful Lima, or head far to the south instead, for rugged mountain landscapes as breath-taking as they are remote.

See all Luxury South America Cruise Deals

Cruises around South America take place year-round, with itineraries ranging anywhere from 7 nights to 62 or more. Shore excursions here offer a huge variety of sights, from city life in Buenos Aires to historic ruins in Machu Picchu. With so many different landscapes, cultures and colonial influences to see, a luxury cruise around South America offers an incredible choice of adventures that you won’t find anywhere else in the world.

With warm weather year-round, there is no one time to enjoy the best cruises around South America. Itineraries range from 7-night Galapagos voyages to month-long tours along the east and west coasts – or you could even opt for a South American cruise that includes Antarctica, Europe, the Caribbean or the Pacific too.

A cruise around South America offers a range of different ways to see the continent. Along with its mix of modern cities, traditional villages and ancient civilisations, the continent is also home to some of the most spectacular landscapes and wildlife on Earth. A cruise to the jungle city of Manaus can open the doors to the Amazon rainforest, while many alternative cruises set sail from Ecuador for the legendary wildlife of the Galapagos.

You will find plenty of exotic and exciting luxury cruises to South America at SixStarCruises™, offering you the chance to set sail on the holiday of a lifetime with one of the world's most popular luxury cruise lines. Call our Cruise Concierge team today and they will help you find your ideal voyage, so you can start looking forward to your next great adventure.

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If you were to close your eyes while enjoying a "high tea in Trafalgar Square," you would swear you were in London - if it weren't for the warm breezes and emerald green waters enveloping you. Nicknamed "Little England" by some, Barbados is home to many museums that chronicle the island's rich past and over 100 shipwrecks along its reefs that are a playground for divers from around the world.

18 Nov 2023


At Sea

19 Nov 2023 - 21 Nov 2023



The first settlement in Santarem was a Jesuit mission built in 1661. Today, Santarem is one of the Amazon's most important trading centers, and is rich in legend and nature. The town is situated at the point where the Tapajos and the Amazon waters meet. This is called the "Wedding of the Waters" and is one of Santarem's major attractions. The lakes and forests of this area are home to numerous species of birds, particularly the white egret.

22 Nov 2023


Boca Da Valeria

Set in the beautiful country of Brazil, Boca da Valeria is a small community located where the Valeria River and Amazon River meets. This village is unparallel to any other Brazilian destination because of the extraordinary and authentic lifestyles of the local Indians. You will not find luxury hotels, restaurants, or even paved roads; instead Boca de Valeria is surrounded by a spirit, beauty, and charm uplifted in the smiles of its brightly dressed children and natives, who welcome their guests with open arms. Boca da Valeria, Brazil is an unusual stop but it is definitely worth the visit, giving everyone in its path an in-depth look into the Amazonian culture.

23 Nov 2023



Manaus, on the banks of the Negro River in northwestern Brazil, is the capital of the vast state of Amazonas. It's a major departure point for the surrounding Amazon Rainforest. Just east of the city, the dark Negro River converges with the brown, muddy Solimões River resulting in a striking visual phenomenon called the “Meeting of the Waters.” The combined tributaries form the Amazon River.

24 Nov 2023 - 25 Nov 2023



Parintins is a municipality in the far east of the Amazonas state, Brazil. It is part of a microregion also named Parintins. The population for the entire municipality was 115,363 and its area is 5,952 km².

26 Nov 2023


Cruise Amazon River

27 Nov 2023


At Sea

28 Nov 2023 - 29 Nov 2023


Fortaleza, Brazil

Along the banks of the creek Pajeú, discover the coastal cosmopolitan charms of Fortaleza. Hugging the Atlantic Ocean in Northeastern Brazil, this is a city shaped by its port. Equal parts industry and culture, here you’ll find a flourishing arts scene and coastal-inspired gastronomy.

30 Nov 2023



Before there was a town there was an impressive star-shaped fort, begun by Portuguese colonizers on the Feast of the Epiphany, and named Forte dos Reis Magos (Fort of the Three Wise Men). This prophetic event was followed by the founding of the town itself on December 25, 1599, hence the name Natal (Christmas). Natal today remains a popular place for holidays, when visitors celebrate the towering sand dunes and crystal blue waters that surround it. A dune buggy ride is just the thing for an adrenaline rush, and Dunas Ecological Park, rich in flora and fauna, is crisscrossed by trails just waiting to be explored.

01 Dec 2023



Named for the surrounding coastal recifes (reefs) offshore, Recife is perched on Brazil's northeast coast. The busy seaport is known as the "Venice of Brazil," thanks to its many waterways, bridges, and small islands. This exciting metropolis is a mix of new high-rises and old colonial structures, with plenty to see and even more to do. Stroll through the historic heart of the city, Recife Antigo, the 16th Experience the city's vibrant cultural, culinary and music scene, or one of its many impressive beaches, such as Porto de Galinhas, a top tourist destination. Or discover the charming town of nearby Olinda, a UNESCO World Heritage Site founded in 1530 by the Portuguese. Recife is also home to a fantastic carnival, but any time of year provides the opportunity to dance the energetic frevo.

02 Dec 2023


At Sea

03 Dec 2023 - 04 Dec 2023


Rio De Janeiro

This dynamic city set on a magnificent bay is famed for its carnival, its natural beauty and friendly people. See the famous Ipanema and Copacabana beaches.Shop till you drop in the modern and sophisticated shopping centre.

05 Dec 2023 - 06 Dec 2023


At Sea

07 Dec 2023 - 08 Dec 2023


Montevideo, Uruguay

Montevideo exudes European charm and elegance, with broad boulevards, fountains, stately squares, and irresistible sidewalk cafes. The city maintains a low-key atmosphere despite its position as Uruguay’s commercial and political hub, and there are few skyscrapers on the horizon, though there are some surprising contrasts – an Art Nouveau pedestrian mall, Art Deco Centenary Stadium, and an American Embassy designed by I.M. Pei. Most of the nation’s countryside is farm or ranchland, and the life of the cowboy, or gaucho, is part of the local lore. Take a peak at the Gaucho Museum, or visit an estancia, and see them in action.

09 Dec 2023


Buenos Aires, Argentina

Welcome to elegant, cosmopolitan Buenos Aires, with its European colonial architecture and colorful mix of cultures. Each district has its own style: enjoy Palermo with its mansions and parks; shop in the chic boutiques of Soho and Hollywood; and soak up the Italian flavor of La Boca where tango dancers and artists display their talents for passersby. Then top it all off with an Argentine steak, perfectly grilled over a fire of glowing coals, and washed down with an excellent glass of Malbec.

10 Dec 2023

(This holiday is generally suitable for persons with reduced mobility. For customers with reduced mobility or any medical condition that may require special assistance or arrangements to be made, please notify your Cruise Concierge at the time of your enquiry, so that we can provide specific information as to the suitability of the holiday, as well as make suitable arrangements with the Holiday Provider on your behalf).


Alternative sailing dates

Flexible with departure dates? Alternative sailing dates for this itinerary are available in the list below

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