Luxury South America Cruises

Luxury cruises in South America are all about the experience. Book one of the cruise deals below and you will have the opportunity to trek through wildlife-rich jungles, marvel at thundering waterfalls, visit ancient Incan ruins, and much more. Depending on the type of cruise you book, you may also get the chance to experience something truly unique, exclusively packaged up with luxury hotel stays and one-of-a-kind tours.

Find Out More About Cruising in South America


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Maya & Inca Discovery
Miami, Florida | Costa Maya | Harvest Caye | Roatán Island | Puerto Limón | Panama City | Panama City | Manta | Salaverry | Callao | Callao
07 Dec 2024
14 Nights
South America

Fly Cruise From

Now: £5682
pp
REF: OCEANIAMNA241207
Sunlit Strands & Icy Lands
Miami, Florida | Costa Maya | Harvest Caye | Roatán Island | Puerto Limón | Panama City | Panama City | Manta | Salaverry | Callao | Callao | Pisco | Coquimbo | San Antonio | More...
07 Dec 2024
38 Nights
World-wide

Fly Cruise From

Now: £11682
pp
REF: OCEANIAMNA241207A
7 Night Galapagos Inner Loop Cruise
Baltra Island, Galápagos | Puerto Egas | Rabida Island | Elizabeth Bay, Isabela Island, Galápagos | Tagus Cove, Isabella Island, Galapagos | Sullivan Bay, Santiago Island, Galápagos | Bartolome Island | Las Bachas, Santa Cruz Island, Galápagos | North Seymour Island, Galapagos | Puerto Baquerizo Moreno, San Cristobal Island, Galapagos | Punta Pitt, San Cristóbal Island, Galápagos | Puerto Ayora, Isla Santa Cruz | Baltra Island, Galápagos
08 Dec 2024
7 Nights
Pacific

Cruise Only From
was: £9780pp
Now: £6086
pp
REF: CELEBFL07G045-081224
Puerto Williams to Puerto Williams
Puerto Williams | Antarctic Sound | Antarctic Peninsula | Antarctic Peninsula | Antarctic Peninsula | South Shetland Islands | Puerto Williams | Puerto Williams
08 Dec 2024
10 Nights
Antarctica

Complimentary one-category Suite upgrade PLUS $1,000 to spend on-board - book now with 15% deposit*
Fly Cruise From

Now: £13943
pp
REF: SILVERWI241208010
Puerto Williams to Puerto Williams
Puerto Williams | Antarctic Sound | Antarctic Peninsula | Antarctic Peninsula | Antarctic Peninsula | South Shetland Islands | Puerto Williams | Puerto Williams
09 Dec 2024
10 Nights
Antarctica

Complimentary one-category Suite upgrade PLUS $1,000 to spend on-board - book now with 15% deposit*
Fly Cruise From

Now: £13179
pp
REF: SILVERE4241209010
Tropical Holiday
Miami, Florida | Georgetown, Grand Cayman | Cartagena | Puntarenas | Corinto | Puerto Quetzal | Acapulco | Cabo San Lucas | Ensenada | Los Angeles, California
13 Dec 2024
16 Nights
Panama Canal

Caribbean Sale - Save up to 30% for a limited time only!
Fly Cruise From
was: £9579pp
Now: £8278
pp
REF: REGENTGRA241213
Caribbean Chic
Cartagena | Santa Marta | Oranjestad | Willemstad | Castries | Gustavia | San Juan (Puerto Rico) | Puerto Plata | Miami, Florida
13 Dec 2024
10 Nights
Caribbean

Fly Cruise From

Now: £2917
pp
REF: OCEANIANAU241213
San Cristóbal to San Cristóbal
San Cristóbal Island, Galápagos | Roca León Dormido | Bartolome Island | Santiago Island, Galápagos | Punta Vicente Roca, Isabela Island, Galápagos | Punta Espinoza, Fernandina Island, Galápagos | Caleta Tagus | Elizabeth Bay, Isabela Island, Galápagos | Post Office Bay, Floreana, Galápagos | Champion Island, Galápagos | Punta Cormorant, Floreana Island, Galápagos | Los Gemelos, Santa Cruz Island, Galápagos | Puerto Ayora, Isla Santa Cruz | Dragon Hill, Santa Cruz Island, Galápagos | More...
14 Dec 2024
7 Nights
Pacific

Complimentary one-category Suite upgrade PLUS $1,000 to spend on-board - book now with 15% deposit*
Fly Cruise From

Now: £9932
pp
REF: SILVEROR241214007
7 Night Galapagos Southern Loop Cruise
Baltra Island, Galápagos | North Seymour Island, Galapagos | South Plaza Island, Galápagos | Santa Fé Island, Galápagos | Punta Pitt, San Cristóbal Island, Galápagos | Puerto Baquerizo Moreno, San Cristobal Island, Galapagos | Floreana Island, Galapagos | Punta Cormorant, Floreana Island, Galápagos | Elizabeth Bay, Isabela Island, Galápagos | Punta Moreno, Isabella Island, Galapagos | Puerto Ayora, Isla Santa Cruz | Gardner Bay, Española Island, Galápagos | Punta Suarez, Isla Española, Galápagos | Baltra Island, Galápagos More...
14 Dec 2024
7 Nights
Pacific

Cruise Only From
was: £7792pp
Now: £6680
pp
REF: CELEBXP07G047-141224
EXCLUSIVE OFFER - Christmas & New Year Celebrations
Fort Lauderdale, Florida | Cartagena | Cartagena | Panama City | Puntarenas | Cabo San Lucas | San Diego, California | Los Angeles, California |
15 Dec 2024
23 Nights
Caribbean

Holiday Prices From
£5149
REF: SILVERSS241217018-2

Cruise & Stay

7 Night Galapagos Outer Loop Cruise
Baltra Island, Galápagos | Gardner Bay, Española Island, Galápagos | Punta Suarez, Isla Española, Galápagos | Punta Cormorant, Floreana Island, Galápagos | Floreana Island, Galapagos | Punta Moreno, Isabella Island, Galapagos | Urbina Bay, Isabella Island, Galapagos | Punta Espinoza, Fernandina Island, Galápagos | Vincente Roca Point, Isabella Island, Galapagos | South Plaza Island, Galápagos | Dragon Hill, Santa Cruz Island, Galápagos | Puerto Ayora, Isla Santa Cruz | Baltra Island, Galápagos
15 Dec 2024
7 Nights
Pacific

Cruise Only From
was: £9780pp
Now: £7605
pp
REF: CELEBFL07G046-151224
Joyful Caribbbean
Miami, Florida | Puerto Plata | San Juan (Puerto Rico) | Gustavia | Pointe-à-Pitre | Castries | Saint John's | Miami, Florida | Costa Maya | Harvest Caye | Roatán Island | Cozumel | Miami, Florida
17 Dec 2024
17 Nights
World-wide

Fly Cruise From
was: £8519pp
Now: £7410
pp
REF: OCEANIAVIS241217A
EXCLUSIVE OFFER - Fort Lauderdale to Los Angeles
Fort Lauderdale, Florida | Cartagena | Cartagena | Panama City | Puntarenas | Cabo San Lucas | San Diego, California | Los Angeles, California
17 Dec 2024
18 Nights
Caribbean

EXCLUSIVE OFFER - FREE flights & FREE 5* hotel stay* | Shore excursions, butler service, complimentary beverages PLUS much more included
Fly Cruise From
was: £7800pp
Now: £4949
pp
REF: SILVERSS241217018
Puerto Williams to Puerto Williams
Puerto Williams | New Island | West Point Island | Port Stanley | South Georgia Island | South Georgia Island | South Georgia Island | Elephant Island, South Shetland Islands | Antarctic Sound | Antarctic Peninsula | Antarctic Peninsula | South Shetland Islands | Puerto Williams | Puerto Williams More...
18 Dec 2024
18 Nights
Antarctica

Complimentary one-category Suite upgrade PLUS $1,000 to spend on-board - book now with 15% deposit*
Fly Cruise From

Now: £23397
pp
REF: SILVERWI241218018
Fort Lauderdale to Lima
Fort Lauderdale, Florida | Oranjestad | Willemstad | Cartagena | Cartagena | Manta | Callao | Callao
19 Dec 2024
16 Nights
South America

Complimentary two-category Suite upgrade PLUS $1,000 to spend on-board - book now with 15% deposit*
$300 FREE to spend on-board - ONLY when booking with SixStarCruises
Fly Cruise From
was: £8600pp
Now: £8213
pp
REF: SILVERRA241219016
Fort Lauderdale to Cartagena
Fort Lauderdale, Florida | Oranjestad | Willemstad | Cartagena | Cartagena
19 Dec 2024
8 Nights
South America

Cruise Only From

Now: £4106
pp
REF: SILVERRA241219S08
Puerto Williams to Puerto Williams
Puerto Williams | Antarctic Sound | Antarctic Peninsula | Antarctic Peninsula | Antarctic Peninsula | South Shetland Islands | Puerto Williams | Puerto Williams
19 Dec 2024
10 Nights
Antarctica

Complimentary one-category Suite upgrade PLUS $1,000 to spend on-board - book now with 15% deposit*
Fly Cruise From

Now: £13752
pp
REF: SILVERE4241219010
17-Night Panama Canal Holiday
Miami, Florida | Cartagena | Cartagena | Puntarenas | Puerto Quetzal | Ixtapa/Zihuatanejo | Cabo San Lucas | San Diego, California | San Diego, California
20 Dec 2024
17 Nights
Caribbean

Extraordinary savings PLUS up to $1000 to spend on-board*
Cruise Only From
was: £5749pp
Now: £2614
pp
REF: AZON17C015-201224
7 Night Galapagos Southern Loop Cruise
Baltra Island, Galápagos | Mosquera Island, Galapagos | Dragon Hill, Santa Cruz Island, Galápagos | Rabida Island | Isabela Island, Galápagos | Puerto Villamil, Isla Isabela | Floreana Island, Galapagos | Punta Cormorant, Floreana Island, Galápagos | San Cristóbal Island, Galápagos | San Cristóbal Island, Galápagos | Puerto Ayora, Isla Santa Cruz | Punta Suarez, Isla Española, Galápagos | Gardner Bay, Española Island, Galápagos | Baltra Island, Galápagos More...
21 Dec 2024
7 Nights
Pacific

Cruise Only From
was: £8940pp
Now: £5815
pp
REF: CELEBXO07G050-211224
7 Night Galapagos Northern Loop Cruise
Baltra Island, Galápagos | Black Turtle Cove, Santa Cruz Island, Galapagos | Rabida Island | Puerto Egas | Tagus Cove, Isabella Island, Galapagos | Punta Espinoza, Fernandina Island, Galápagos | Urbina Bay, Isabella Island, Galapagos | Vincente Roca Point, Isabella Island, Galapagos | Bartolome Island | Las Bachas, Santa Cruz Island, Galápagos | El Barranco, Genovesa Island, Galápagos | Darwin Bay, Genovesa Island, Galápagos | Puerto Ayora, Isla Santa Cruz | Baltra Island, Galápagos More...
21 Dec 2024
7 Nights
Pacific

Cruise Only From
was: £9421pp
Now: £7703
pp
REF: CELEBXP07G048-211224
Mangroves Of The Maya
Miami, Florida | Costa Maya | Harvest Caye | Roatán Island | Puerto Limón | Colón | Cartagena | Willemstad | Oranjestad | Castries | Bridgetown
21 Dec 2024
14 Nights
Caribbean

Fly Cruise From

Now: £5154
pp
REF: OCEANIASIR241221
Caribbean Amazon Culture
Miami, Florida | Costa Maya | Harvest Caye | Roatán Island | Puerto Limón | Colón | Cartagena | Willemstad | Oranjestad | Castries | Bridgetown | Scarborough | Santarém | Boca de Valeria | More...
21 Dec 2024
32 Nights
World-wide

Fly Cruise From

Now: £8571
pp
REF: OCEANIASIR241221A
Antarctic & Patagonian Joy
Callao | Pisco | Coquimbo | San Antonio | Puerto Montt | Puerto Chacabuco | Laguna San Rafael National Park | Punta Arenas | Ushuaia | Port Stanley | Punta del Este | Buenos Aires | Buenos Aires
21 Dec 2024
24 Nights
South America

Fly Cruise From

Now: £7515
pp
REF: OCEANIAMNA241221
Captivating South America
Callao | Pisco | Coquimbo | San Antonio | Puerto Montt | Puerto Chacabuco | Laguna San Rafael National Park | Punta Arenas | Ushuaia | Port Stanley | Punta del Este | Buenos Aires | Buenos Aires | Buenos Aires | More...
21 Dec 2024
36 Nights
World-wide

Fly Cruise From

Now: £9474
pp
REF: OCEANIAMNA241221A
Christmas & New Year in the Caribbean - Barbados to Fort Lauderdale
Bridgetown | Scarborough | Castries | Port Elizabeth, Bequia | Willemstad | Oranjestad | Cartagena | Cartagena | Colón | Roatán Island | Belize City | Cozumel | Fort Lauderdale, Florida
21 Dec 2024
16 Nights
Caribbean

Complimentary two-category Suite upgrade PLUS $1,000 to spend on-board - book now with 15% deposit*
$200 FREE to spend on-board - ONLY when booking with SixStarCruises
Fly Cruise From
was: £10500pp
Now: £10027
pp
REF: SILVERMO241221016
7 Night Galapagos Inner Loop Cruise
Baltra Island, Galápagos | Puerto Egas | Rabida Island | Elizabeth Bay, Isabela Island, Galápagos | Tagus Cove, Isabella Island, Galapagos | Sullivan Bay, Santiago Island, Galápagos | Bartolome Island | Las Bachas, Santa Cruz Island, Galápagos | North Seymour Island, Galapagos | Puerto Baquerizo Moreno, San Cristobal Island, Galapagos | Punta Pitt, San Cristóbal Island, Galápagos | Puerto Ayora, Isla Santa Cruz | Baltra Island, Galápagos
22 Dec 2024
7 Nights
Pacific

Cruise Only From
was: £15556pp
Now: £9718
pp
REF: CELEBFL07G045-221224
Puerto Williams to King George Island
Puerto Williams | Port Stanley | New Island | West Point Island | South Georgia Island | South Georgia Island | South Georgia Island | Antarctic Sound | Antarctic Peninsula | Antarctic Peninsula | Antarctic Peninsula | King George Island, South Shetland Islands
22 Dec 2024
15 Nights
Antarctica

Complimentary one-category Suite upgrade PLUS $1,000 to spend on-board - book now with 15% deposit*
Fly Cruise From

Now: £28077
pp
REF: SILVEREV241222015
11 Night Canal & Caribbean Holiday
Fort Lauderdale, Florida | Cartagena | Colón | Kralendijk | Oranjestad | Willemstad | Fort Lauderdale, Florida
23 Dec 2024
11 Nights
Panama Canal

Fly Cruise From

Now: £8846
pp
REF: CELEBBY11C018-231224
Beyond The Panama Canal
Miami, Florida | Great Stirrup Cay | Cartagena | Puntarenas | Corinto | Puerto Quetzal | Acapulco | Cabo San Lucas | Ensenada | Los Angeles, California
23 Dec 2024
16 Nights
Panama Canal

Olife Choice AVAILABLE ON EVERY BOOKING - $800 to spend on-board OR 8 FREE shore excursions or FREE beverage package
HUGE savings, FREE pre-paid gratuities worth up to $23pppd & FREE on-board spend - EXCLUSIVE to SixStarCruises
Fly Cruise From
was: £4519pp
Now: £3723
pp
REF: OCEANIANAU241223

Explore South America on a Finest Collection voyage

Our Finest Collection cruise packages in South America offer tailor-made adventures exclusively for you. Your cruise is paired with a set of immersive land tours dedicated to helping you get right to the heart of the ports on your itinerary. What's more, after days spent hiking across glaciers or exploring iconic cities accompanied by a local tour guide, you can retire to a five-star hotel for a gourmet dinner and spot of well-earned relaxation. 

South America expedition cruises

If you want your South America cruise adventure to be even more unforgettable, embark on an expedition cruise and feel like a true explorer. Sailing to destinations like mysterious Easter Island, wild and rugged Chile, and the positively prehistoric Galapagos islands; once-in-a-lifetime experiences are guaranteed. Accompanied by a dedicated group of expedition experts - from marine biologists to professional adventurers - you willl live like an intrepid explorer and witness natural wonders most people can only dream of.

Book South America cruises with our Cruise Concierge team

If you would like to embark on an adventure you will never forget, call our Cruise Concierge team to book one of the itineraries below. And if you can't find exactly what you are looking for? Call us to build a completely bespoke cruise in South America that incorporates every port and experience you have been dreaming of.

Our Award Winning Service


Travel Weekly Large Cruise Agency of the Year 2023
Travel Weekly Large Cruise Agency of the Year 2023
Best Luxury Travel Agent 2022
Best Luxury Travel Agent 2022
UK Cruise Awards Winners 2023
UK Cruise Awards Winners 2023
Best Specialist Cruise Agent 2023
Best Specialist Cruise Agent 2023
Best Use Of Content 2023
Best Use Of Content 2023
TTG Luxury Cruise Agency Of The Year
TTG Luxury Cruise Agency Of The Year

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