Panama Canal Luxury Cruises

Browse all available sailing dates for luxury cruise holidays to the Panama Canal. To find out more and to discover the best deals call us today and speak to our cruise experts. All Pnama Canal cruise holidays are fully ABTA & ATOL protected.

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New Orleans, Miami Beach and Panama Canal Passage
Miami, Florida | Cartagena | Puntarenas | Puerto Quetzal | Puerto Chiapas | Huatulco (Santa María Huatulco) | Cabo San Lucas | Los Angeles, California
02 Nov 2024
25 Nights
Seabourn Quest
Panama Canal
HOLIDAY PRICES FROM

Now: £13449 pp
REF: SBN6467-2

Cruise & Stay

Amazonian & Tropical Song
Miami, Florida | Saint John's | Castries | Saint George's | Port-of-Spain | Macapa | Santarém | Boca de Valeria | Manaus | Parintins | Alter do Chão | Macapa | Bridgetown | Roseau | More...
09 Nov 2024
44 Nights
Oceania Nautica
South America
Fly Cruise From
Was £17949pp
Now: £14619 pp
REF: OCEANIANAU241109B
18-Day Panama Canal Passage
Miami, Florida | Cartagena | Puntarenas | Puerto Quetzal | Puerto Chiapas | Huatulco (Santa María Huatulco) | Cabo San Lucas | Los Angeles, California
09 Nov 2024
18 Nights
Seabourn Quest
Panama Canal
Cruise Only From
Was £9498pp
Now: £7415 pp
REF: SBN6467
Panama Canal Voyage with Panama Stay
Miami, Florida | Oranjestad | Kralendijk | Willemstad | Cartagena | Fuerte Amador | Fuerte Amador
02 Dec 2024
15 Nights
Azamara Journey
Panama Canal
Amazing prices you just cant miss - very limited availability at these prices
HOLIDAY PRICES FROM
Was £3699pp
Now: £3389 pp
REF: AZJR10C013-031224-2

Cruise & Stay

11 Night Panama Canal & S Caribbean
Fort Lauderdale, Florida | Cartagena | Colón | Oranjestad | Kralendijk | Georgetown, Grand Cayman | Fort Lauderdale, Florida
02 Dec 2024
11 Nights
Celebrity Beyond
Panama Canal
Cruise118.com EXCLUSIVE! Up to $500 FREE to spend on-board per stateroom
At least 30% OFF PLUS £100pp airfare credit and add Drinks & Wi-Fi from £59pp per day
Online Exclusive! Save more when you book online - for a limited time only
Fly Cruise From
Was £7441pp
Now: £5618 pp
REF: CELEBBY11C017-021224
10-Night Panama Canal Voyage
Miami, Florida | Oranjestad | Kralendijk | Willemstad | Cartagena | Fuerte Amador | Fuerte Amador
03 Dec 2024
10 Nights
Azamara Journey
Panama Canal
Amazing prices you just cant miss - very limited availability at these prices
Fly Cruise From
Was £3470pp
Now: £2677 pp
REF: AZJR10C013-031224
Western Caribbean Bliss
Miami, Florida | Costa Maya | Harvest Caye | Santo Tomás de Castilla | Roatán Island | Puerto Limón | Colón | Cartagena | Cartagena
03 Dec 2024
10 Nights
Oceania Nautica
Caribbean
Summer Sale - Save up to 40%*
Fly Cruise From
Was £3059pp
Now: £2906 pp
REF: OCEANIANAU241203
Caribbean Panorama
Miami, Florida | Costa Maya | Harvest Caye | Santo Tomás de Castilla | Roatán Island | Puerto Limón | Colón | Cartagena | Cartagena | Santa Marta | Oranjestad | Willemstad | Castries | Gustavia | More...
03 Dec 2024
20 Nights
Oceania Nautica
Caribbean
Fly Cruise From
Was £4299pp
Now: £3501 pp
REF: OCEANIANAU241203A
South America Kaleidoscope
Miami, Florida | Costa Maya | Harvest Caye | Roatán Island | Puerto Limón | Panama City | Panama City | Manta | Salaverry | Callao | Callao | Pisco | Coquimbo | San Antonio | More...
07 Dec 2024
50 Nights
Oceania Marina
South America
Fly Cruise From
Was £15359pp
Now: £14591 pp
REF: OCEANIAMNA241207B
Maya & Inca Discovery
Miami, Florida | Costa Maya | Harvest Caye | Roatán Island | Puerto Limón | Panama City | Panama City | Manta | Salaverry | Callao | Callao
07 Dec 2024
14 Nights
Oceania Marina
South America
Fly Cruise From
Was £5889pp
Now: £4796 pp
REF: OCEANIAMNA241207
Sunlit Strands & Icy Lands
Miami, Florida | Costa Maya | Harvest Caye | Roatán Island | Puerto Limón | Panama City | Panama City | Manta | Salaverry | Callao | Callao | Pisco | Coquimbo | San Antonio | More...
07 Dec 2024
38 Nights
Oceania Marina
World-wide
Fly Cruise From
Was £12089pp
Now: £9846 pp
REF: OCEANIAMNA241207A
EXCLUSIVE OFFER - Panama City Stay with Panama Canal Voyage
Fuerte Amador | Puerto Limón | Roatán Island | Santo Tomás de Castilla | Costa Maya | Cozumel | Miami, Florida
09 Dec 2024
14 Nights
Azamara Journey
Panama Canal
Amazing prices you just cant miss - very limited availability at these prices
HOLIDAY PRICES FROM
Was £2769pp
Now: £2569 pp
REF: AZJR241213-009-2

Cruise & Stay

9-Night Panama Canal Voyage
Fuerte Amador | Puerto Limón | Roatán Island | Santo Tomás de Castilla | Costa Maya | Cozumel | Miami, Florida
13 Dec 2024
9 Nights
Azamara Journey
Panama Canal
Amazing prices you just cant miss - very limited availability at these prices
Fly Cruise From
Was £3032pp
Now: £2144 pp
REF: AZJR241213-009
Tropical Holiday
Miami, Florida | Georgetown, Grand Cayman | Cartagena | Puntarenas | Corinto | Puerto Quetzal | Acapulco | Cabo San Lucas | Ensenada | Los Angeles, California
13 Dec 2024
16 Nights
Seven Seas Grandeur
Panama Canal
Ultimate All-Inclusive Cruise Fare now includes: Round-trip Economy flights, transfers between airport and ship PLUS Private Executive Chauffeur Credit*
Fly Cruise From
Was £9109pp
Now: £8653 pp
REF: REGENTGRA241213
Fort Lauderdale to Los Angeles
Fort Lauderdale, Florida | Cartagena | Cartagena | Panama City | Puntarenas | Cabo San Lucas | San Diego, California | Los Angeles, California
17 Dec 2024
18 Nights
Silver Shadow
Caribbean
Fly Cruise From
Was £8900pp
Now: £6027 pp
REF: SILVERSS241217018
Fort Lauderdale to Fuerte Amador
Fort Lauderdale, Florida | Cartagena | Cartagena | Panama City
17 Dec 2024
7 Nights
Silver Shadow
Caribbean
Cruise Only From
Was £13450pp
Now: £10955 pp
REF: SILVERSS241217S07
17-Night Panama Canal Holiday
Miami, Florida | Cartagena | Cartagena | Puntarenas | Puerto Quetzal | Ixtapa/Zihuatanejo | Cabo San Lucas | San Diego, California | San Diego, California
20 Dec 2024
17 Nights
Azamara Onward
Panama Canal
Fly Cruise From
Was £5444pp
Now: £4129 pp
REF: AZON17C015-201224
Mangroves Of The Maya
Miami, Florida | Costa Maya | Harvest Caye | Roatán Island | Puerto Limón | Colón | Cartagena | Willemstad | Oranjestad | Castries | Bridgetown
21 Dec 2024
14 Nights
Oceania Sirena
Caribbean
Summer Sale - Save up to 40%*
Fly Cruise From
Was £5189pp
Now: £3547 pp
REF: OCEANIASIR241221
Caribbean Amazon Culture
Miami, Florida | Costa Maya | Harvest Caye | Roatán Island | Puerto Limón | Colón | Cartagena | Willemstad | Oranjestad | Castries | Bridgetown | Scarborough | Santarém | Boca de Valeria | More...
21 Dec 2024
32 Nights
Oceania Sirena
Caribbean
Fly Cruise From
Was £8839pp
Now: £7199 pp
REF: OCEANIASIR241221A
Christmas & New Year in the Caribbean - Barbados to Fort Lauderdale
Bridgetown | Scarborough | Castries | Port Elizabeth, Bequia | Willemstad | Oranjestad | Cartagena | Cartagena | Colón | Roatán Island | Belize City | Cozumel | Fort Lauderdale, Florida
21 Dec 2024
16 Nights
Silver Moon
Caribbean
Save up to £3000 per couple PLUS 15% deposit* - HURRY ENDS 31st July
$300 FREE to spend on-board - ONLY when booking with SixStarCruises
Fly Cruise From
Was £10800pp
Now: £7575 pp
REF: SILVERMO241221016
11 Night Canal & Caribbean Holiday
Fort Lauderdale, Florida | Cartagena | Colón | Willemstad | Oranjestad | Georgetown, Grand Cayman | Fort Lauderdale, Florida
23 Dec 2024
11 Nights
Celebrity Beyond
Panama Canal
Cruise118.com EXCLUSIVE! Up to $500 FREE to spend on-board per stateroom
At least 30% OFF PLUS £100pp airfare credit and add Drinks & Wi-Fi from £59pp per day
Online Exclusive! Save more when you book online - for a limited time only
Cruise118.com Exclusive! Include Classic Drinks Package and Wi-Fi
Fly Cruise From
Was £10311pp
Now: £7331 pp
REF: CELEBBY11C018-231224
Beyond The Panama Canal
Miami, Florida | Great Stirrup Cay | Cartagena | Puntarenas | Corinto | Puerto Quetzal | Acapulco | Cabo San Lucas | Ensenada | Los Angeles, California
23 Dec 2024
16 Nights
Oceania Nautica
Panama Canal
Fly Cruise From
Was £4459pp
Now: £3631 pp
REF: OCEANIANAU241223
Fuerte Amador to Los Angeles
Panama City | Puntarenas | Cabo San Lucas | San Diego, California | Los Angeles, California
24 Dec 2024
11 Nights
Silver Shadow
Caribbean
Cruise Only From
Was £5700pp
Now: £4642 pp
REF: SILVERSS241224S11
Cartagena to Fort Lauderdale
Cartagena | Cartagena | Colón | Roatán Island | Belize City | Cozumel | Fort Lauderdale, Florida
29 Dec 2024
8 Nights
Silver Moon
Caribbean
Cruise Only From
Was £9850pp
Now: £6033 pp
REF: SILVERMO241229S08
South America & Panama Canal - Lima to Fort Lauderdale
Callao | Callao | Guayaquil | Panama City | Cartagena | Cartagena | Oranjestad | Fort Lauderdale, Florida
04 Jan 2025
16 Nights
Silver Ray
South America
Fly Cruise From
Was £9200pp
Now: £5702 pp
REF: SILVERRA250104016

Prices are subject to change and availability. Prices may vary depending on airport selected. Promotions are only applicable to select cabins grades, please call for details

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