Panama Canal Luxury Cruises

Browse all available sailing dates for luxury cruise holidays to the Panama Canal. To find out more and to discover the best deals call us today and speak to our cruise experts. All Pnama Canal cruise holidays are fully ABTA & ATOL protected.

Find Out More About Panama Canal Cruising

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Fly Cruise From:
Was £89990pp Now: £86390pp

Viking World Cruise

Fort Lauderdale | Cozumel | Cartagena | Colón | Puntarenas | Cabo San Lucas | Los Angeles | Honolulu | Kailua-Kona | Vaitape | Papeete | Rarotonga | Wellington | Napier | Tauranga | Auckland | Sydney | Brisbane | Airlie Beach | Cairns | Thursday Island | Darwin | Rinca Island | Benoa | Semarang | Jakarta | Singapore | Port Klang | Langkawi Island | Georgetown | Phuket | Colombo | Male | Victoria | Mombasa | Zanzibar | Hell-Ville | Maputo | Richards Bay | Durban | East London | Gqeberha (ex Port Elizabeth) | Cape Town | Lüderitz | Walvis Bay | Luanda | Lagos | Accra | Takoradi | Dakar | Mindelo | Puerto de la Estaca | Agadir | Casablanca | Cádiz | Lisbon | Porto | La Coruña | Honfleur | Dover | London (Greenwich)

  • 22 Dec 2026
  • 141 Nights
Fly Cruise From:
Was £89990pp Now: £86390pp
View cruise Enquire Enquire
REF: VIKINGOSK261222D
Fly Cruise From:
Was £110990pp Now: £106550pp

Viking World Voyage III

Fort Lauderdale | Cozumel | Cartagena | Colón | Puntarenas | Cabo San Lucas | Los Angeles | Honolulu | Kailua-Kona | Vaitape | Papeete | Rarotonga | Wellington | Napier | Tauranga | Auckland | Sydney | Brisbane | Airlie Beach | Cairns | Thursday Island | Darwin | Rinca Island | Benoa | Semarang | Jakarta | Singapore | Port Klang | Langkawi Island | Georgetown | Phuket | Colombo | Male | Victoria | Mombasa | Zanzibar | Hell-Ville | Maputo | Richards Bay | Durban | East London | Gqeberha (ex Port Elizabeth) | Cape Town | Lüderitz | Walvis Bay | Luanda | Lagos | Accra | Takoradi | Dakar | Mindelo | Puerto de la Estaca | Agadir | Casablanca | Cádiz | Lisbon | Porto | La Coruña | Honfleur | Dover | London (Greenwich) | Dover | Holyhead | Liverpool | Dun Laoghaire | Belfast | Ullapool | Kirkwall | Newhaven/Edinburgh | Aberdeen | Lerwick | Bergen | Eidfjord | Stavanger | Oslo | Aalborg | Copenhagen | Warnemünde | Rønne | Gdansk | Tallinn | Stockholm

  • 22 Dec 2026
  • 169 Nights
Fly Cruise From:
Was £110990pp Now: £106550pp
View cruise Enquire Enquire
REF: VIKINGOSK261222F
Fly Cruise From:
Was £5795pp Now: £5563pp

Panama Canal & Central America

West Palm Beach | Montego Bay | Cartagena | Colón | Limon | Belize City | Cozumel | Fort Lauderdale

  • 27 Dec 2026
  • 14 Nights
Fly Cruise From:
Was £5795pp Now: £5563pp
View cruise Enquire Enquire
REF: VIKINGOMA261227
Fly Cruise From:
Was £12099pp Now: £11494pp

Panama Canal & Pacific Gems

Miami | Georgetown | Cartagena | Puntarenas | Puerto Quetzal | Acapulco | Cabo San Lucas | San Diego | Los Angeles

  • 29 Dec 2026
  • 16 Nights
Book now with a 7.5% low deposit*
Fly Cruise From:
Was £12099pp Now: £11494pp
View cruise Enquire Enquire
REF: REGENTGRA261229
Cruise From:
£7960pp

Secrets of Central America

Puntarenas | Curú Wildlife Refuge | Bahía Drake | Coiba Island | Darién National Park | Pearl Islands | San Blas Islands | Fuerte San Lorenzo | Colón

  • 04 Jan 2027
  • 10 Nights
Cruise From:
£7960pp
View cruise Enquire Enquire
REF: PONANTEE040127
Fly Cruise From:
Was £24179pp Now: £23453pp

South America Discovery

Hamburg | Rotterdam | Zeebrugge | Southampton | Hamilton | Port Canaveral | Fort Lauderdale | Grand Turk Island | Bridgetown | Fortaleza | Salvador de Bahia | Buzios | Rio de Janeiro | Santos | Montevideo | Buenos Aires | Puerto Madryn | Ushuaia | Cape Horn | Punta Arenas | PIO X Glacier | Puerto Montt | San Antonio | Coquimbo | Arica | Callao | Manta | Fuerte Amador | Aruba | Fort Lauderdale | Port Canaveral | Ponta Delgada | Southampton | Zeebrugge | Hamburg

  • 05 Jan 2027
  • 90 Nights
Fly Cruise From:
Was £24179pp Now: £23453pp
View cruise Enquire Enquire
REF: CUNARDH702E
Cruise From:
Was £26128pp Now: £20280pp

62-Day World Cruise: Panama Canal, Polynesia & New Zealand

Miami | Guayaquil | Machala | Callao | General San Martin | Iquique | Hangaroa | Nuku Hiva Island | Hiva Oa Island | Fakarava | Avatiu | Papeete | Moorea | Bora-Bora | Aitutaki | Nuku'alofa | Whangarei | Auckland | Tauranga | Napier | Wellington | Picton | Kaikoura | Christchurch | Timaru | Port Chalmers | Oban | Sydney

  • 05 Jan 2027
  • 62 Nights
Receive up to $1,000 onboard spend per couple
Cruise From:
Was £26128pp Now: £20280pp
View cruise Enquire Enquire
REF: SBN6711C
Cruise From:
Was £14508pp Now: £12912pp

35-Day World Cruise: Panama Canal Crossing & Polynesia

Miami | Guayaquil | Machala | Callao | General San Martin | Iquique | Hangaroa | Nuku Hiva Island | Hiva Oa Island | Fakarava | Avatiu | Papeete

  • 05 Jan 2027
  • 35 Nights
Receive up to $1,000 onboard spend per couple
Cruise From:
Was £14508pp Now: £12912pp
View cruise Enquire Enquire
REF: SBN6711D
Fly Cruise From:
£3814pp

Panama Potpourri

Miami | Cozumel | Costa Maya | Harvest Caye | Santo Tomás de Castilla | Roatán Island | Puerto Limón | Panama City | Puerto Limón | Panama City

  • 05 Jan 2027
  • 10 Nights
Save up to 50%* - book before prices increase!
Choose between FREE Wine, Beer & Champagne by the glass with lunch and dinner OR shore excursion credit
Fly Cruise From:
£3814pp
View cruise Enquire Enquire
REF: OCEANIAMNA270105
Fly Cruise From:
Was £8339pp Now: £7880pp

Panama Canal & Caribbean

Miami | Cozumel | Costa Maya | Harvest Caye | Santo Tomás de Castilla | Roatán Island | Puerto Limón | Panama City | Puerto Limón | Panama City | Cartagena | Santa Marta | Oranjestad | Willemstad | Falmouth | Georgetown | Miami

  • 05 Jan 2027
  • 20 Nights
Choose between FREE Wine, Beer & Champagne by the glass with lunch and dinner OR shore excursion credit
Fly Cruise From:
Was £8339pp Now: £7880pp
View cruise Enquire Enquire
REF: OCEANIAMNA270105A
Cruise From:
£7960pp

Secrets of Central America

Puntarenas | Curú Wildlife Refuge | Bahía Drake | Coiba Island | Darién National Park | Pearl Islands | San Blas Islands | Fuerte San Lorenzo | Colón

  • 05 Jan 2027
  • 10 Nights
Cruise From:
£7960pp
View cruise Enquire Enquire
REF: PONANTER050127
Fly Cruise From:
£7069pp

Treasures Of Two Oceans

Miami | Georgetown | Cartagena | Puerto Quetzal | Acapulco | Manzanillo | San Diego | Los Angeles

  • 06 Jan 2027
  • 15 Nights
Choose between FREE Wine, Beer & Champagne by the glass with lunch and dinner OR shore excursion credit
Fly Cruise From:
£7069pp
View cruise Enquire Enquire
REF: OCEANIAVIS270106

DEPARTS FROM UK

Cruise From:
Was £19999pp Now: £19399pp

South America Discovery

Southampton | Hamilton | Port Canaveral | Fort Lauderdale | Grand Turk Island | Bridgetown | Fortaleza | Salvador de Bahia | Buzios | Rio de Janeiro | Santos | Montevideo | Buenos Aires | Puerto Madryn | Ushuaia | Cape Horn | Punta Arenas | PIO X Glacier | Puerto Montt | San Antonio | Coquimbo | Arica | Callao | Manta | Fuerte Amador | Aruba | Fort Lauderdale | Port Canaveral | Ponta Delgada | Southampton

  • 10 Jan 2027
  • 82 Nights
Cruise From:
Was £19999pp Now: £19399pp
View cruise Enquire Enquire
REF: CUNARDH703B
Fly Cruise From:
Was £8779pp Now: £8515pp

Southampton to Los Angeles

Southampton | New York | Aruba | Acajutla | Puerto Vallarta | Los Angeles

  • 10 Jan 2027
  • 26 Nights
Fly Cruise From:
Was £8779pp Now: £8515pp
View cruise Enquire Enquire
REF: CUNARDV703A
Fly Cruise From:
Was £5695pp Now: £5467pp

Panama Canal & Central America

Fort Lauderdale | Montego Bay | Colón | Limon | Roatán Island | Belize City | Cozumel | Fort Lauderdale

  • 10 Jan 2027
  • 14 Nights
Receive a FREE Silver Spirits Drinks Package on ALL Ocean and Expedition voyages
Fly Cruise From:
Was £5695pp Now: £5467pp
View cruise Enquire Enquire
REF: VIKINGOMA270110
Fly Cruise From:
Was £74254pp Now: £70541pp

Navigate The World

Miami | Cozumel | Costa Maya | Harvest Caye | Roatán Island | Georgetown | Ocho Rios | Puerto Limón | Cartagena | Panama City | Cartagena | Panama City | Puntarenas | Acajutla | Puerto Quetzal | Puerto Vallarta | Cabo San Lucas | Los Angeles | Honolulu | Kahului-Maui | Hilo | Bora-Bora | Papeete | Moorea | Papeete | Moorea | Huahine | Uturoa | Bora-Bora | Pago Pago | Apia | Suva | Lautoka | Mystery Island (Inyeug) | Lifou Island | Nouméa | Sydney | Townsville | Cairns | Cooktown | Darwin | Komodo Island | Benoa | Surabaya | Semarang | Singapore | Port Klang | Georgetown | Phuket | Colombo | Male | Cochin | Mangalore | Mormugao | Mumbai (ex Bombay) | Muscat | Dubai | Doha | Abu Dhabi | Salalah | Jeddah | Safaga | 'Aqaba | Haifa | Limassol | Rhodes | Kusadasi | Piraeus | Sorrento | Civitavecchia

  • 11 Jan 2027
  • 127 Nights
Book now with a 7.5% low deposit*
Fly Cruise From:
Was £74254pp Now: £70541pp
View cruise Enquire Enquire
REF: REGENTSPL270111F
Fly Cruise From:
Was £81559pp Now: £77481pp

World Of Splendor

Miami | Cozumel | Costa Maya | Harvest Caye | Roatán Island | Georgetown | Ocho Rios | Puerto Limón | Cartagena | Panama City | Cartagena | Panama City | Puntarenas | Acajutla | Puerto Quetzal | Puerto Vallarta | Cabo San Lucas | Los Angeles | Honolulu | Kahului-Maui | Hilo | Bora-Bora | Papeete | Moorea | Papeete | Moorea | Huahine | Uturoa | Bora-Bora | Pago Pago | Apia | Suva | Lautoka | Mystery Island (Inyeug) | Lifou Island | Nouméa | Sydney | Townsville | Cairns | Cooktown | Darwin | Komodo Island | Benoa | Surabaya | Semarang | Singapore | Port Klang | Georgetown | Phuket | Colombo | Male | Cochin | Mangalore | Mormugao | Mumbai (ex Bombay) | Muscat | Dubai | Doha | Abu Dhabi | Salalah | Jeddah | Safaga | 'Aqaba | Haifa | Limassol | Rhodes | Kusadasi | Piraeus | Sorrento | Civitavecchia | Tarragona | Alicante | Málaga | Casablanca | Halifax | New York

  • 11 Jan 2027
  • 141 Nights
Book now with a 7.5% low deposit*
Fly Cruise From:
Was £81559pp Now: £77481pp
View cruise Enquire Enquire
REF: REGENTSPL270111G
Fly Cruise From:
Was £12094pp Now: £9533pp

Tropical Treasures

Miami | Cozumel | Costa Maya | Harvest Caye | Roatán Island | Georgetown | Ocho Rios | Puerto Limón | Cartagena | Panama City | Cartagena | Panama City

  • 12 Jan 2027
  • 14 Nights
Exquisite Escapes Sale - Save up to 50%*
Book now with a 7.5% low deposit*
Fly Cruise From:
Was £12094pp Now: £9533pp
View cruise Enquire Enquire
REF: REGENTSPL270112
Fly Cruise From:
Was £27879pp Now: £19178pp

Tides To Tahiti

Miami | Cozumel | Costa Maya | Harvest Caye | Roatán Island | Georgetown | Ocho Rios | Puerto Limón | Cartagena | Panama City | Cartagena | Panama City | Puntarenas | Acajutla | Puerto Quetzal | Puerto Vallarta | Cabo San Lucas | Los Angeles | Honolulu | Kahului-Maui | Hilo | Bora-Bora | Papeete | Moorea | Papeete

  • 12 Jan 2027
  • 42 Nights
Exquisite Escapes Sale - Save up to 50%*
Book now with a 7.5% low deposit*
Fly Cruise From:
Was £27879pp Now: £19178pp
View cruise Enquire Enquire
REF: REGENTSPL270112A
Cruise From:
Was £21969pp Now: £21090pp

Circle South America Grand Voyage

Miami | Saint John Island | Charlotte Amalie | Philipsburg | Charlestown | Saint John's | Saint Pierre | Port Elizabeth | Saint George's | Bridgetown | Scarborough | Isle Royale | Belem | Recife | Salvador de Bahia | Buzios | Rio de Janeiro | Parati | Ilhabela | São Paulo | Montevideo | Buenos Aires | Montevideo | Punta del Este | Port Stanley | Ushuaia | Punta Arenas | Chilean Fjords | Puerto Chacabuco | Puerto Montt | San Antonio | Coquimbo | Iquique | Arica | Pisco | Callao | Fuerte Amador | Puerto Limón | San Andrés Island | Cozumel | Miami

  • 14 Jan 2027
  • 74 Nights
Included in your Grand Voyage: Complimentary Airfare | Shore Excursion Credit | Upgrade Beverage package | WiFi for Two Devices | Weekly Laundry Service
Cruise From:
Was £21969pp Now: £21090pp
View cruise Enquire Enquire
REF: AZJR270114-074
Cruise From:
£9753pp

Secrets of Central America

Colón | Fuerte San Lorenzo | San Blas Islands | Pearl Islands | Darién National Park | Coiba Island | Bahía Drake | Curú Wildlife Refuge | Puntarenas

  • 14 Jan 2027
  • 10 Nights
Cruise From:
£9753pp
View cruise Enquire Enquire
REF: PONANTEE140127
Fly Cruise From:
Was £3989pp Now: £3299pp

Panama To Caribbean Joy

Panama City | Cartagena | Santa Marta | Oranjestad | Willemstad | Falmouth | Georgetown | Miami

  • 15 Jan 2027
  • 10 Nights
Save up to 50%* - book before prices increase!
Choose between FREE Wine, Beer & Champagne by the glass with lunch and dinner OR shore excursion credit
Fly Cruise From:
Was £3989pp Now: £3299pp
View cruise Enquire Enquire
REF: OCEANIAMNA270115
Cruise From:
£5030pp

Central America Jewels & Panama Canal

Colón | San Blas Islands | Portobelo | Darién National Park | Golfito | Puntarenas

  • 15 Jan 2027
  • 7 Nights
Cruise From:
£5030pp
View cruise Enquire Enquire
REF: PONANTER150127
Fly Cruise From:
Was £7919pp Now: £7681pp

New York to Los Angeles

New York | Aruba | Acajutla | Puerto Vallarta | Los Angeles

  • 19 Jan 2027
  • 17 Nights
NEW! Low deposit from ONLY £100pp*
Fly Cruise From:
Was £7919pp Now: £7681pp
View cruise Enquire Enquire
REF: CUNARDV704
Fly Cruise From:
Was £18099pp Now: £17556pp

South America Discovery From Fort Lauderdale

Fort Lauderdale | Grand Turk Island | Bridgetown | Fortaleza | Salvador de Bahia | Buzios | Rio de Janeiro | Santos | Montevideo | Buenos Aires | Puerto Madryn | Ushuaia | Cape Horn | Punta Arenas | PIO X Glacier | Puerto Montt | San Antonio | Coquimbo | Arica | Callao | Manta | Fuerte Amador | Aruba | Fort Lauderdale

  • 22 Jan 2027
  • 56 Nights
Fly Cruise From:
Was £18099pp Now: £17556pp
View cruise Enquire Enquire
REF: CUNARDH704B
Fly Cruise From:
Was £11049pp Now: £8710pp

Ultimate Panama Canal Transit

Los Angeles | Cabo San Lucas | Puerto Vallarta | Puerto Quetzal | Puntarenas | Cartagena | Georgetown | Miami

  • 24 Jan 2027
  • 16 Nights
EXCLUSIVE $400 onboard spend* - ONLY when booking with SixStarCruises
Book now with a 7.5% low deposit*
Fly Cruise From:
Was £11049pp Now: £8710pp
View cruise Enquire Enquire
REF: REGENTGRA270124
Fly Cruise From:
Was £18294pp Now: £11545pp

Canal To Coral Reefs

Panama City | Puntarenas | Acajutla | Puerto Quetzal | Puerto Vallarta | Cabo San Lucas | Los Angeles | Honolulu | Kahului-Maui | Hilo | Bora-Bora | Papeete | Moorea | Papeete

  • 26 Jan 2027
  • 28 Nights
Exquisite Escapes Sale - Save up to 50%*
Book now with a 7.5% low deposit*
Fly Cruise From:
Was £18294pp Now: £11545pp
View cruise Enquire Enquire
REF: REGENTSPL270126
Fly Cruise From:
Was £7074pp Now: £6720pp

Sapphire Sojourn

Los Angeles | Cabo San Lucas | Mazatlán | Acapulco | Puerto Quetzal | Puntarenas | Panama City

  • 10 Feb 2027
  • 12 Nights
Book now with a 7.5% low deposit*
Fly Cruise From:
Was £7074pp Now: £6720pp
View cruise Enquire Enquire
REF: REGENTPRT270210
Cruise From:
Was £12629pp Now: £12123pp

Buenos Aires to Miami Grand Voyage

Buenos Aires | Montevideo | Punta del Este | Port Stanley | Ushuaia | Punta Arenas | Chilean Fjords | Puerto Chacabuco | Puerto Montt | San Antonio | Coquimbo | Iquique | Arica | Pisco | Callao | Fuerte Amador | Puerto Limón | San Andrés Island | Cozumel | Miami

  • 17 Feb 2027
  • 40 Nights
Included in your Grand Voyage: Complimentary Airfare | Shore Excursion Credit | Upgrade Beverage package | WiFi for Two Devices | Weekly Laundry Service
Cruise From:
Was £12629pp Now: £12123pp
View cruise Enquire Enquire
REF: AZJR270217-040
Cruise From:
£6040pp

Panama and Costa Rica by Sea: The Natural Wonders of Central America – with Smithsonian Journeys

Puntarenas | Quepos (Puerto Quepos) | Darién National Park | Fuerte Amador | San Blas Islands | Colón

  • 19 Feb 2027
  • 7 Nights
Cruise From:
£6040pp
View cruise Enquire Enquire
REF: PONANTER190227

Prices are subject to change and availability. Prices may vary depending on the airport selected. Promotions are only applicable to select cabin grades, please call for details.

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