Panama Canal Luxury Cruises

Browse all available sailing dates for luxury cruise holidays to the Panama Canal. To find out more and to discover the best deals call us today and speak to our cruise experts. All Pnama Canal cruise holidays are fully ABTA & ATOL protected.

Find Out More About Panama Canal Cruising

Showing 30 out of 230 cruises
Per Person
Total Price
Fly Cruise From:
Was £4290pp Now: £4118pp

Fort Lauderdale | Progreso | Cozumel | Belize City | Limon | Colón | Fuerte Amador

  • 06 Jan 2028
  • 10 Nights
Fly Cruise From:
Was £4290pp Now: £4118pp
REF: VIKINGOMA280106
Cruise From:
Was £58599pp Now: £52153pp

Miami | Fuerte Amador | Guayaquil | Salaverry | Callao | General San Martin | Hangaroa | San Juan Bautista (Robinson Crusoe Island) | Santa Clara Island | Valparaiso | Puerto Montt | Castro | Puerto Chacabuco | PIO X Glacier | El Brujo Glacier | Punta Arenas | Garibaldi Glacier | Ushuaia | Antarctic Experience | Falkland Islands | Port Stanley | Montevideo | Buenos Aires | Tristan da Cunha | Nightingale Islands | Richards Bay | Maputo | Durban | Gqeberha (ex Port Elizabeth) | Mossel Bay | Cape Town | Lüderitz | Walvis Bay | Luanda | Sao Tome Island | Cotonou | Tema | Takoradi | Dakar | Mindelo | Las Palmas de Gran Canaria | Arrecife | Casablanca | Tangier | Cádiz | Lisbon | Porto | La Coruña | Saint-Malo | Cherbourg | Rouen | Southampton

  • 07 Jan 2028
  • 120 Nights
Cruise From:
Was £58599pp Now: £52153pp
REF: SBN6810A
Cruise From:
Was £54699pp Now: £48682pp

Miami | Fuerte Amador | Guayaquil | Salaverry | Callao | General San Martin | Hangaroa | San Juan Bautista (Robinson Crusoe Island) | Santa Clara Island | Valparaiso | Puerto Montt | Castro | Puerto Chacabuco | PIO X Glacier | El Brujo Glacier | Punta Arenas | Garibaldi Glacier | Ushuaia | Antarctic Experience | Falkland Islands | Port Stanley | Montevideo | Buenos Aires | Tristan da Cunha | Nightingale Islands | Richards Bay | Maputo | Durban | Gqeberha (ex Port Elizabeth) | Mossel Bay | Cape Town | Lüderitz | Walvis Bay | Luanda | Sao Tome Island | Cotonou | Tema | Takoradi | Dakar | Mindelo | Las Palmas de Gran Canaria | Arrecife | Casablanca | Tangier | Cádiz | Lisbon

  • 07 Jan 2028
  • 112 Nights
Cruise From:
Was £54699pp Now: £48682pp
REF: SBN6810B
Cruise From:
Was £40038pp Now: £35633pp

Miami | Fuerte Amador | Guayaquil | Salaverry | Callao | General San Martin | Hangaroa | San Juan Bautista (Robinson Crusoe Island) | Santa Clara Island | Valparaiso | Puerto Montt | Castro | Puerto Chacabuco | PIO X Glacier | El Brujo Glacier | Punta Arenas | Garibaldi Glacier | Ushuaia | Antarctic Experience | Falkland Islands | Port Stanley | Montevideo | Buenos Aires | Tristan da Cunha | Nightingale Islands | Richards Bay | Maputo | Durban | Gqeberha (ex Port Elizabeth) | Mossel Bay | Cape Town

  • 07 Jan 2028
  • 82 Nights
Cruise From:
Was £40038pp Now: £35633pp
REF: SBN6810C
Cruise From:
Was £27458pp Now: £24437pp

Miami | Fuerte Amador | Guayaquil | Salaverry | Callao | General San Martin | Hangaroa | San Juan Bautista (Robinson Crusoe Island) | Santa Clara Island | Valparaiso | Puerto Montt | Castro | Puerto Chacabuco | PIO X Glacier | El Brujo Glacier | Punta Arenas | Garibaldi Glacier | Ushuaia | Antarctic Experience | Falkland Islands | Port Stanley | Montevideo | Buenos Aires

  • 07 Jan 2028
  • 57 Nights
Cruise From:
Was £27458pp Now: £24437pp
REF: SBN6810D
Cruise From:
Was £3740pp Now: £3553pp

Fort Lauderdale | Cartagena | Colón | Puerto Limón | Roatán Island | Cozumel | Fort Lauderdale

  • 08 Jan 2028
  • 10 Nights
Cruise From:
Was £3740pp Now: £3553pp
REF: CRYSTALCSE-010-280108
Fly Cruise From:
Was £7779pp Now: £7545pp

Hamburg | Southampton | Ponta Delgada | Port Canaveral | Miami | Cartagena | Puerto Quetzal | Manzanillo | Los Angeles

  • 09 Jan 2028
  • 29 Nights
Fly Cruise From:
Was £7779pp Now: £7545pp
REF: CUNARDH802D
Fly Cruise From:
Was £6059pp Now: £5877pp

Southampton | Ponta Delgada | Port Canaveral | Miami | Cartagena | Puerto Quetzal | Manzanillo | Los Angeles

  • 11 Jan 2028
  • 27 Nights
Fly Cruise From:
Was £6059pp Now: £5877pp
REF: CUNARDH803A
Cruise From:
Was £55000pp Now: £52250pp

Fort Lauderdale | Cozumel | Belize City | Santo Tomás de Castilla | Roatán Island | Puerto Limón | Cartagena | Fuerte Amador | Cartagena | Fuerte Amador | Manta | Guayaquil | Salaverry | Callao | Hangaroa | Adamstown | Fakarava | Rangiroa | Huahine | Papeete | Moorea | Raiatea | Bora-Bora | Pago Pago | Suva | Lautoka | Port Vila | Lifou Island | Nouméa | Pine Island | Bay of Islands | Auckland | Napier | Wellington | Melbourne | Portland | Adelaide | Kangaroo Island | Albany | Fremantle | Geraldton | Bali | Celukan Bawang | Puerto Princesa | Boracay Island | Manila | Nha Trang | Ho Chi Minh City | Singapore | Port Klang | Georgetown | Phuket | Port Blair | Hambantota | Colombo | Cochin | New Mangalore | Goa | Mumbai (ex Bombay) | Khasab | Abu Dhabi | Dubai | Fujairah | Muscat | Salalah | Jeddah | 'Aqaba | Luxor | Alexandria | Soúda | Katakolon | Siracuse | Valletta | Tunis | Trapani | Lipari | Sorrento | Civitavecchia | Barcelona | Alicante | Motril | Ponta Delgada | Horta | Kings Wharf | Fort Lauderdale

  • 11 Jan 2028
  • 150 Nights
Cruise From:
Was £55000pp Now: £52250pp
REF: CRYSTALCSY-W150-280111
Cruise From:
Was £53000pp Now: £50350pp

Fort Lauderdale | Cozumel | Belize City | Santo Tomás de Castilla | Roatán Island | Puerto Limón | Cartagena | Fuerte Amador | Cartagena | Fuerte Amador | Manta | Guayaquil | Salaverry | Callao | Hangaroa | Adamstown | Fakarava | Rangiroa | Huahine | Papeete | Moorea | Raiatea | Bora-Bora | Pago Pago | Suva | Lautoka | Port Vila | Lifou Island | Nouméa | Pine Island | Bay of Islands | Auckland | Napier | Wellington | Melbourne | Portland | Adelaide | Kangaroo Island | Albany | Fremantle | Geraldton | Bali | Celukan Bawang | Puerto Princesa | Boracay Island | Manila | Nha Trang | Ho Chi Minh City | Singapore | Port Klang | Georgetown | Phuket | Port Blair | Hambantota | Colombo | Cochin | New Mangalore | Goa | Mumbai (ex Bombay) | Khasab | Abu Dhabi | Dubai | Fujairah | Muscat | Salalah | Jeddah | 'Aqaba | Luxor | Alexandria | Soúda | Katakolon | Siracuse | Valletta | Tunis | Trapani | Lipari | Sorrento | Civitavecchia | Barcelona

  • 11 Jan 2028
  • 136 Nights
Cruise From:
Was £53000pp Now: £50350pp
REF: CRYSTALCSY-W136-280111
Cruise From:
Was £34900pp Now: £33155pp

Fort Lauderdale | Cozumel | Belize City | Santo Tomás de Castilla | Roatán Island | Puerto Limón | Cartagena | Fuerte Amador | Cartagena | Fuerte Amador | Manta | Guayaquil | Salaverry | Callao | Hangaroa | Adamstown | Fakarava | Rangiroa | Huahine | Papeete | Moorea | Raiatea | Bora-Bora | Pago Pago | Suva | Lautoka | Port Vila | Lifou Island | Nouméa | Pine Island | Bay of Islands | Auckland | Napier | Wellington | Melbourne | Portland | Adelaide | Kangaroo Island | Albany | Fremantle | Geraldton | Bali | Celukan Bawang | Puerto Princesa | Boracay Island | Manila | Nha Trang | Ho Chi Minh City | Singapore

  • 11 Jan 2028
  • 85 Nights
Cruise From:
Was £34900pp Now: £33155pp
REF: CRYSTALCSY-G85-280111
Cruise From:
Was £9519pp Now: £9043pp

Fort Lauderdale | Cozumel | Belize City | Santo Tomás de Castilla | Roatán Island | Puerto Limón | Cartagena | Fuerte Amador | Cartagena | Fuerte Amador | Manta | Guayaquil | Salaverry | Callao | Hangaroa | Adamstown | Fakarava | Rangiroa | Huahine | Papeete

  • 11 Jan 2028
  • 33 Nights
Cruise From:
Was £9519pp Now: £9043pp
REF: CRYSTALCSY-C33-280111
Cruise From:
Was £6184pp Now: £5874pp

Fort Lauderdale | Cozumel | Belize City | Santo Tomás de Castilla | Roatán Island | Puerto Limón | Cartagena | Fuerte Amador | Cartagena | Fuerte Amador | Manta | Guayaquil | Salaverry | Callao

  • 11 Jan 2028
  • 18 Nights
Cruise From:
Was £6184pp Now: £5874pp
REF: CRYSTALCSY-018-280111
Cruise From:
£4920pp

Colón | Portobelo | San Blas Islands | Balboa (Panama City) | Quepos (Puerto Quepos) | Puntarenas

  • 12 Jan 2028
  • 7 Nights
Cruise From:
£4920pp
REF: PONANTEG120128
Fly Cruise From:
Was £9829pp Now: £9435pp

Bridgetown | Port Elizabeth | Mayreau Island | Kralendijk | Willemstad | Oranjestad | Santa Marta | Cartagena | San Blas Islands | Panama City

  • 13 Jan 2028
  • 11 Nights
Fly Cruise From:
Was £9829pp Now: £9435pp
REF: EMERALDE02C130128-2
Fly Cruise From:
Was £15507pp Now: £14886pp

Bridgetown | Port Elizabeth | Mayreau Island | Kralendijk | Willemstad | Oranjestad | Santa Marta | Cartagena | San Blas Islands | Panama City | Pearl Islands | Darién National Park | Playa del Muerto | Cébaco Island | Golfito | Quepos (Puerto Quepos) | Tortuga Island | Puerto Caldera

  • 13 Jan 2028
  • 18 Nights
Fly Cruise From:
Was £15507pp Now: £14886pp
REF: EMERALD2C02130128-2

Finest Collection

Holiday prices from:
£9199pp

A Journey South with Machu Picchu Discovery

Miami | Cozumel | Puerto Limón | Colón | Manta | Callao

  • 14 Jan 2028
  • 19 Nights
Holiday prices from:
£9199pp
REF: SILVERRA280115012-2
Experience the 'Lost City of the Incas'
Tours included in Cuzco and Lima
5* hotel stays in Miami, Cuzco & Lima

Finest Collection

Holiday prices from:
£10599pp

Crossing Continents and Cultures Cruise with Beauty of the Amazon Land Tour

Miami | Cozumel | Puerto Limón | Colón | Manta | Callao

  • 14 Jan 2028
  • 19 Nights
Holiday prices from:
£10599pp
REF: SILVERRA280115012-3
Three-night stay at Inkaterra Reserva Amazónica, Tambopata Province, Madre de Dios to explore the beauty of the Amazon
Cruise From:
Was £2439pp Now: £2341pp

Fuerte Amador | Manta | Callao | Pisco | Coquimbo | Valparaiso

  • 14 Jan 2028
  • 10 Nights
Cruise From:
Was £2439pp Now: £2341pp
REF: AZQS280114-010
Cruise From:
Was £9500pp Now: £9025pp

Miami | Cozumel | Puerto Limón | Colón | Manta | Callao

  • 15 Jan 2028
  • 12 Nights
Cruise From:
Was £9500pp Now: £9025pp
REF: SILVERRA280115012
Cruise From:
Was £6200pp Now: £5890pp

Cartagena | Panama City | Cartagena | Panama City | Manta | Callao | Valparaiso

  • 15 Jan 2028
  • 14 Nights
Cruise From:
Was £6200pp Now: £5890pp
REF: SILVERSS280115014
Fly Cruise From:
Was £4390pp Now: £4214pp

Fuerte Amador | Colón | Limon | Belize City | Cozumel | Progreso | Fort Lauderdale

  • 16 Jan 2028
  • 10 Nights
Fly Cruise From:
Was £4390pp Now: £4214pp
REF: VIKINGOMA280116
Fly Cruise From:
Was £3799pp Now: £3590pp

Panama City | Cartagena | Willemstad | Oranjestad | Montego Bay | Georgetown | Miami

  • 16 Jan 2028
  • 10 Nights
Fly Cruise From:
Was £3799pp Now: £3590pp
REF: OCEANIAMNA280116
Fly Cruise From:
Was £5945pp Now: £5707pp

Panama City | Pearl Islands | Darién National Park | Playa del Muerto | Cébaco Island | Golfito | Quepos (Puerto Quepos) | Tortuga Island | Puerto Caldera

  • 24 Jan 2028
  • 7 Nights
Fly Cruise From:
Was £5945pp Now: £5707pp
REF: EMERALDE01C240128-2
Fly Cruise From:
Was £5290pp Now: £5078pp

Fort Lauderdale | Montego Bay | Colón | Limon | Roatán Island | Belize City | Cozumel | Fort Lauderdale

  • 26 Jan 2028
  • 14 Nights
Fly Cruise From:
Was £5290pp Now: £5078pp
REF: VIKINGOMA280126
Fly Cruise From:
Was £5390pp Now: £5174pp

Fort Lauderdale | Montego Bay | Colón | Limon | Roatán Island | Belize City | Cozumel | Fort Lauderdale

  • 09 Feb 2028
  • 14 Nights
Fly Cruise From:
Was £5390pp Now: £5174pp
REF: VIKINGOMA280209
Fly Cruise From:
Was £10025pp Now: £9624pp

San José | Puerto Limón | San José | Puerto Limón | Bocas del Toro | Panama City | Bocas del Toro | Panama City | Pearl Islands | Darién National Park | Playa del Muerto | Cébaco Island | Golfito | Quepos (Puerto Quepos) | Puerto Caldera | Curú Wildlife Refuge | Puerto Caldera

  • 10 Feb 2028
  • 12 Nights
Fly Cruise From:
Was £10025pp Now: £9624pp
REF: EMERALDE03C100228-2
Cruise From:
Was £9140pp Now: £8683pp

Fort Lauderdale | Road Town | Gustavia | Roseau | Basseterre | San Juan (Puerto Rico) | Saint John's | Pointe-à-Pitre | Castries | Saint George's | Kralendijk | Willemstad | Oranjestad | Cartagena | Colón | Puerto Limón | Roatán Island | Santo Tomás de Castilla | Belize City | Cozumel | Fort Lauderdale

  • 12 Feb 2028
  • 27 Nights
Cruise From:
Was £9140pp Now: £8683pp
REF: CRYSTALCSE-C27-280212
Cruise From:
Was £3257pp Now: £3094pp

Fort Lauderdale | Oranjestad | Willemstad | Colón | Georgetown | Fort Lauderdale

  • 14 Feb 2028
  • 11 Nights

Interest free Monthly Payments from JUST £147pp

Cruise From:
Was £3257pp Now: £3094pp
REF: CELEBAT11C027-140228
Fly Cruise From:
Was £15358pp Now: £14743pp

Puerto Caldera | Tortuga Island | Quepos (Puerto Quepos) | Golfito | Cébaco Island | Darién National Park | Playa del Muerto | Pearl Islands | Panama City | San Blas Islands | Cartagena | Santa Marta | Oranjestad | Willemstad | Kralendijk | Mayreau Island | Port Elizabeth | Bridgetown

  • 22 Feb 2028
  • 18 Nights
Fly Cruise From:
Was £15358pp Now: £14743pp
REF: EMERALD2C02220228-1

Prices are subject to change and availability. Prices may vary depending on the airport selected. Promotions are only applicable to select cabin grades, please call for details.

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UK Cruise Awards 2026 Partnership Achievement Award
UK Cruise Awards 2026 Partnership Achievement Award
Luxury Cruise Agency of the Year 2025
Luxury Cruise Agency of the Year 2025
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TTG Top 20 Luxury Travel Agents 2025
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UK Cruise Awards Winners 2023
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Travel Weekly Large Cruise Agency of the Year 2023
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