Luxury South America Cruises

Luxury cruises in South America are all about the experience. Book one of the cruise deals below and you will have the opportunity to trek through wildlife-rich jungles, marvel at thundering waterfalls, visit ancient Incan ruins, and much more. Depending on the type of cruise you book, you may also get the chance to experience something truly unique, exclusively packaged up with luxury hotel stays and one-of-a-kind tours.

Find Out More About Cruising in South America

Showing 30 out of 1079 cruises
Per Person
Total Price
Cruise From:
£6040pp

Puntarenas | Quepos (Puerto Quepos) | Darién National Park | Fuerte Amador | San Blas Islands | Colón

  • 19 Feb 2027
  • 7 Nights
Cruise From:
£6040pp
REF: PONANTER190227
Cruise From:
Was £14097pp Now: £12546pp

Buenos Aires | Ushuaia | Antarctic Experience | Buenos Aires | Ushuaia

  • 20 Feb 2027
  • 11 Nights
Cruise From:
Was £14097pp Now: £12546pp
REF: SBNV719
Cruise From:
Was £12000pp Now: £11400pp

San Cristóbal Island | Roca León Dormido | Bartolome Island | Santiago Island | Punta Vicente Roca | Punta Espinoza | Elizabeth Bay | Caleta Tagus | Champion Island | Post Office Bay | Punta Cormorant | Los Gemelos | Puerto Ayora | Santa Cruz Island | Isla Guy Fawkes | Dragon Hill | San Cristóbal Island

  • 20 Feb 2027
  • 7 Nights
Cruise From:
Was £12000pp Now: £11400pp
REF: SILVEROR270220007
Fly Cruise From:
Was £9118pp Now: £8662pp

Buenos Aires | Port Stanley | Ushuaia | Punta Arenas | Puerto Montt | San Antonio | Callao

  • 20 Feb 2027
  • 18 Nights
Fly Cruise From:
Was £9118pp Now: £8662pp
REF: REGENTMAR270220
Fly Cruise From:
Was £12990pp Now: £12470pp

Ushuaia | Antarctic Experience | Antarctica | Antarctic Experience | Antarctica | Ushuaia

  • 20 Feb 2027
  • 11 Nights
Fly Cruise From:
Was £12990pp Now: £12470pp
REF: VIKINGXOC270220T
Cruise From:
Was £21800pp Now: £20710pp

King George Island | Antarctic Sound | Antarctic Peninsula | South Shetland Islands | Puerto Williams

  • 20 Feb 2027
  • 9 Nights
Cruise From:
Was £21800pp Now: £20710pp
REF: SILVERWI270220009
Cruise From:
Was £14397pp Now: £12813pp

Buenos Aires | Ushuaia | Antarctic Experience | Buenos Aires | Ushuaia

  • 21 Feb 2027
  • 11 Nights
Cruise From:
Was £14397pp Now: £12813pp
REF: SBNP718
Cruise From:
Was £7387pp Now: £7017pp

Baltra Island | Punta Suarez | Gardner Bay | Floreana Island | Punta Cormorant | Elizabeth Bay | Urbina Bay | Vincente Roca Point | Punta Espinoza | Daphne Major | South Plaza Island | Dragon Hill | Puerto Ayora | Baltra Island

  • 21 Feb 2027
  • 7 Nights
Cruise From:
Was £7387pp Now: £7017pp
REF: CELEBFL07G060-210227
Fly Cruise From:
Was £9354pp Now: £8040pp

Miami | Costa Maya | Harvest Caye | Roatán Island | Georgetown | Ocho Rios | Puerto Limón | Cartagena | Colón | Panama City | Colón | Panama City

  • 23 Feb 2027
  • 14 Nights
Fly Cruise From:
Was £9354pp Now: £8040pp
REF: REGENTGRA270223
Fly Cruise From:
Was £7995pp Now: £7675pp

Valparaiso | Puerto Montt | Punta Arenas | Ushuaia | Port Stanley | Puerto Madryn | Montevideo | Buenos Aires

  • 25 Feb 2027
  • 17 Nights
Fly Cruise From:
Was £7995pp Now: £7675pp
REF: VIKINGOJU270225
Fly Cruise From:
Was £18388pp Now: £16618pp

Buenos Aires | Ushuaia | Antarctic Peninsula | Ushuaia | Buenos Aires | Ushuaia

  • 25 Feb 2027
  • 12 Nights
Fly Cruise From:
Was £18388pp Now: £16618pp
REF: SCENIC101S250227-1
Fly Cruise From:
Was £26295pp Now: £25243pp

Buenos Aires | Ushuaia | Antarctic Peninsula | Ushuaia | Buenos Aires | Ushuaia | Buenos Aires | Iguazú Falls | Rio de Janeiro | Iguazú Falls | Rio de Janeiro

  • 25 Feb 2027
  • 21 Nights
Fly Cruise From:
Was £26295pp Now: £25243pp
REF: SCENICOSA1250227-1
Fly Cruise From:
Was £52795pp Now: £50683pp

Buenos Aires | Ushuaia | Antarctic Peninsula | Ushuaia | Cape Horn | Chilean Fjords | Punta Arenas | Puerto Edén | PIO X Glacier | Castro | Puerto Montt | Niebla | Valparaiso | Pingüino de Humboldt National Reserve | Paracas | Salaverry | Manta | Utría National Park | Ensenada de Utria | Darién National Park | Playa del Muerto | Panama City | San Blas Islands | Cartagena | Cabo de la Vela | Willemstad | Tobago Cays | Mayreau Island | Soufrière | Bridgetown

  • 25 Feb 2027
  • 48 Nights
Fly Cruise From:
Was £52795pp Now: £50683pp
REF: SCENIC104S250227-1
Cruise From:
£13640pp

Ushuaia | Antarctic Peninsula | South Georgia Island | Port Stanley | Puerto Madryn | Buenos Aires

  • 26 Feb 2027
  • 18 Nights
Cruise From:
£13640pp
REF: PONANTAU260227
Cruise From:
£4790pp

Colón | San Blas Islands | Fuerte Amador | Darién National Park | Golfito | Puntarenas

  • 26 Feb 2027
  • 7 Nights
Cruise From:
£4790pp
REF: PONANTER260227
Cruise From:
Was £11500pp Now: £10925pp

San Cristóbal Island | Roca León Dormido | El Barranco | Darwin Bay | Sullivan Bay | North Seymour Island | Punta Moreno | Mangle Point | Los Gemelos | Puerto Ayora | Punta Suarez | Gardner Bay | Cerro Brujo | San Cristóbal Island

  • 27 Feb 2027
  • 7 Nights
Cruise From:
Was £11500pp Now: £10925pp
REF: SILVEROR270227007
Fly Cruise From:
Was £12990pp Now: £12470pp

Ushuaia | Antarctic Experience | Antarctica | Antarctic Experience | Antarctica | Ushuaia

  • 27 Feb 2027
  • 11 Nights
Fly Cruise From:
Was £12990pp Now: £12470pp
REF: VIKINGXPO270227T
Cruise From:
Was £8000pp Now: £7600pp

Puerto Williams | Ushuaia | Punta Arenas | Aguila Glacier | Chilean Fjords | Caleta Tortel | Chilean Fjords | Puerto Cisnes | Puerto Montt | Valparaiso

  • 27 Feb 2027
  • 11 Nights
Cruise From:
Was £8000pp Now: £7600pp
REF: SILVERE4270227011
Cruise From:
Was £5499pp Now: £5334pp

San Antonio | Coquimbo | Arica | Callao | Manta | Fuerte Amador | Aruba | Fort Lauderdale

  • 28 Feb 2027
  • 19 Nights
Cruise From:
Was £5499pp Now: £5334pp
REF: CUNARDH706
Fly Cruise From:
Was £9109pp Now: £8835pp

San Antonio | Coquimbo | Arica | Callao | Manta | Fuerte Amador | Aruba | Fort Lauderdale | Port Canaveral | Ponta Delgada | Southampton

  • 28 Feb 2027
  • 33 Nights
Fly Cruise From:
Was £9109pp Now: £8835pp
REF: CUNARDH706A
Fly Cruise From:
Was £10199pp Now: £9893pp

San Antonio | Coquimbo | Arica | Callao | Manta | Fuerte Amador | Aruba | Fort Lauderdale | Port Canaveral | Ponta Delgada | Southampton | Zeebrugge | Hamburg

  • 28 Feb 2027
  • 36 Nights
Fly Cruise From:
Was £10199pp Now: £9893pp
REF: CUNARDH706B
Fly Cruise From:
Was £13505pp Now: £11916pp

Buenos Aires | Ushuaia | Cape Horn | Chilean Fjords | Aguila Glacier | Tuckers Islets | Magdalena Island | Admiralty Bay | Punta Arenas | Isla Pinguino | Punta Piramides | Montevideo | Buenos Aires

  • 28 Feb 2027
  • 17 Nights
Fly Cruise From:
Was £13505pp Now: £11916pp
REF: SCENIC701L280227-2
Fly Cruise From:
Was £19560pp Now: £18777pp

Buenos Aires | Ushuaia | Cape Horn | Chilean Fjords | Aguila Glacier | Tuckers Islets | Magdalena Island | Admiralty Bay | Punta Arenas | Isla Pinguino | Punta Piramides | Montevideo | Buenos Aires | Iguazú Falls | Rio de Janeiro | Iguazú Falls | Rio de Janeiro

  • 28 Feb 2027
  • 26 Nights
Fly Cruise From:
Was £19560pp Now: £18777pp
REF: SCENICOLA7280227-2
Cruise From:
Was £7610pp Now: £7229pp

Baltra Island | Rabida Island | Puerto Egas | Elizabeth Bay | Tagus Cove | Bartolome Island | Sullivan Bay | Daphne Major | North Seymour Island | Las Bachas | Punta Pitt | Puerto Baquerizo Moreno | Puerto Ayora | Baltra Island

  • 28 Feb 2027
  • 7 Nights
Cruise From:
Was £7610pp Now: £7229pp
REF: CELEBFL07G059-280227
Cruise From:
£11760pp

Ushuaia | Antarctic Peninsula | Ushuaia

  • 28 Feb 2027
  • 10 Nights
Cruise From:
£11760pp
REF: PONANTLY280227

Finest Collection

Holiday prices from:
£5499pp

Amazing Iguazu Falls & Luxury South America Cruise

Buenos Aires | Montevideo | Punta del Este | Rio Grande | Florianópolis | Itajai | Santos | Parati | Ilha Grande | Buzios | Rio de Janeiro

  • 01 Mar 2027
  • 19 Nights
Holiday prices from:
£5499pp
REF: OCEANIAINS270307-3
Luxury hotel stays included in Iguazu Falls & Buenos Aires
Discover the stunning beauty of Iguazu Falls with a tour
10-night luxury South America Cruise from Buenos Aires to Rio de Janiero
Return flights from London included!
Cruise From:
Was £16200pp Now: £15390pp

Puerto Williams | Antarctic Sound | Antarctic Peninsula | South Shetland Islands | King George Island

  • 01 Mar 2027
  • 9 Nights
Cruise From:
Was £16200pp Now: £15390pp
REF: SILVERWI270301009
Fly Cruise From:
Was £24418pp Now: £21732pp

Buenos Aires | Ushuaia | Antarctic Experience | South Georgia Experience | Port Stanley | Falkland Islands | Buenos Aires | Ushuaia

  • 02 Mar 2027
  • 21 Nights
Fly Cruise From:
Was £24418pp Now: £21732pp
REF: SBNV722
Cruise From:
£25797pp

Buenos Aires | Ushuaia | Antarctic Experience | South Georgia Experience | Port Stanley | Falkland Islands | Ushuaia | Falkland Islands | Port Stanley | Falkland Islands | Puerto Madryn | Montevideo | Camboriú | Rio de Janeiro

  • 02 Mar 2027
  • 35 Nights
Cruise From:
£25797pp
REF: SBNV722A
Cruise From:
Was £34097pp Now: £30346pp

Buenos Aires | Ushuaia | Antarctic Experience | South Georgia Experience | Port Stanley | Falkland Islands | Ushuaia | Falkland Islands | Port Stanley | Falkland Islands | Puerto Madryn | Montevideo | Camboriú | Rio de Janeiro | Salvador de Bahia | Recife | Natal | Praia | Mindelo | Tenerife | Arrecife | Tangier | Seville

  • 02 Mar 2027
  • 56 Nights
Cruise From:
Was £34097pp Now: £30346pp
REF: SBNV722B

Prices are subject to change and availability. Prices may vary depending on the airport selected. Promotions are only applicable to select cabin grades, please call for details.

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UK Cruise Awards 2026 Partnership Achievement Award
UK Cruise Awards 2026 Partnership Achievement Award
Luxury Cruise Agency of the Year 2025
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