Luxury South America Cruises

Luxury cruises in South America are all about the experience. Book one of the cruise deals below and you will have the opportunity to trek through wildlife-rich jungles, marvel at thundering waterfalls, visit ancient Incan ruins, and much more. Depending on the type of cruise you book, you may also get the chance to experience something truly unique, exclusively packaged up with luxury hotel stays and one-of-a-kind tours.

Find Out More About Cruising in South America

Showing 30 out of 965 cruises
Per Person
Total Price
Fly Cruise From:
Was £8990pp Now: £8630pp

New York | San Salvador Island | Inagua | Port Antonio | Fuerte Amador | Callao | Iquique | Valparaiso

  • 17 Oct 2027
  • 19 Nights
Fly Cruise From:
Was £8990pp Now: £8630pp
REF: VIKINGXOC271017

Cruise & Stay

Holiday prices from:
£7649pp

Icons of the Americas: San Juan to Rio de Janeiro with 5* Hotel Stays

San Juan (Puerto Rico) | Basseterre | Castries | Scarborough | Iles du Salut | Fortaleza | Maceió | Salvador de Bahia | Rio de Janeiro

  • 18 Oct 2027
  • 21 Nights
Holiday prices from:
£7649pp
REF: CRYSTALCSE-014-271021-2
5* Luxury Hotel Stays in San Juan and Rio de Janeiro
14-night ultra-luxury all-inclusive cruise
Flights and selected private overseas transfers
Cruise From:
Was £14897pp Now: £13258pp

San Antonio | Puerto Montt | Caleta Tortel | PIO X Glacier | Caleta Tortel | PIO X Glacier | El Brujo Glacier | Punta Arenas | Antarctic Experience | Ushuaia | Buenos Aires | Ushuaia

  • 18 Oct 2027
  • 18 Nights
Cruise From:
Was £14897pp Now: £13258pp
REF: SBNP758
Fly Cruise From:
Was £9315pp Now: £8942pp

Bridgetown | Soufrière | Port Elizabeth | Mayreau Island | Tobago Cays | Willemstad | Cabo de la Vela | Cartagena | San Blas Islands | Panama City | San Blas Islands | Panama City

  • 20 Oct 2027
  • 11 Nights
Fly Cruise From:
Was £9315pp Now: £8942pp
REF: SCENIC131C201027-1
Cruise From:
Was £5298pp Now: £5033pp

San Juan (Puerto Rico) | Basseterre | Castries | Scarborough | Iles du Salut | Fortaleza | Maceió | Salvador de Bahia | Rio de Janeiro

  • 21 Oct 2027
  • 14 Nights
Cruise From:
Was £5298pp Now: £5033pp
REF: CRYSTALCSE-014-271021
Fly Cruise From:
Was £6195pp Now: £5947pp

Bridgetown | Rio de Janeiro

  • 23 Oct 2027
  • 11 Nights
Fly Cruise From:
Was £6195pp Now: £5947pp
REF: SCENIC141R231027-1
Cruise From:
£4770pp

Las Palmas de Gran Canaria | Rio de Janeiro | Ushuaia

  • 23 Oct 2027
  • 21 Nights
Cruise From:
£4770pp
REF: PONANTBO231027
Cruise From:
Was £7787pp Now: £7397pp

Baltra Island | Rabida Island | Puerto Egas | Elizabeth Bay | Tagus Cove | Bartolome Island | Sullivan Bay | Daphne Major | North Seymour Island | Las Bachas | Punta Pitt | Puerto Baquerizo Moreno | Puerto Ayora | Baltra Island

  • 24 Oct 2027
  • 7 Nights
Cruise From:
Was £7787pp Now: £7397pp
REF: CELEBFL07G059-241027
Fly Cruise From:
Was £6999pp Now: £6614pp

Miami | Georgetown | Cartagena | Puntarenas | Puerto Quetzal | Acapulco | Puerto Vallarta | Mazatlán | Cabo San Lucas | Los Angeles

  • 24 Oct 2027
  • 18 Nights
Fly Cruise From:
Was £6999pp Now: £6614pp
REF: OCEANIAVIS271024
Fly Cruise From:
Was £21639pp Now: £20448pp

Miami | Georgetown | Cartagena | Puntarenas | Puerto Quetzal | Acapulco | Puerto Vallarta | Mazatlán | Cabo San Lucas | Los Angeles | Hilo | Kahului-Maui | Honolulu | Bora-Bora | Huahine | Papeete | Bora-Bora | Rarotonga | Aitutaki | Alofi | Vava'u | Port Denarau | Lautoka | Mystery Island (Inyeug) | Nouméa | Cairns | Townsville | Airlie Beach | Brisbane | Sydney

  • 24 Oct 2027
  • 59 Nights
Fly Cruise From:
Was £21639pp Now: £20448pp
REF: OCEANIAVIS271024C
Cruise From:
Was £18197pp Now: £16195pp

Rio de Janeiro | Camboriú | Montevideo | Falkland Islands | Port Stanley | South Georgia Experience | Antarctic Experience | Ushuaia | Buenos Aires | Ushuaia

  • 25 Oct 2027
  • 25 Nights
Cruise From:
Was £18197pp Now: £16195pp
REF: SBNV760
Cruise From:
£22500pp

Ushuaia | Antarctic Peninsula | Ushuaia

  • 27 Oct 2027
  • 12 Nights
Cruise From:
£22500pp
REF: PONANTCC271027
Cruise From:
£8350pp

Valparaiso | Quemchi | Caleta Tortel | PIO X Glacier | El Brujo Glacier | Estero las Montanas | Tuckers Islets | Alberto de Agostini National Park | Garibaldi Glacier | Cape Horn | Puerto Williams | Ushuaia

  • 28 Oct 2027
  • 14 Nights
Cruise From:
£8350pp
REF: PONANTAU281027
Fly Cruise From:
Was £9655pp Now: £9268pp

Panama City | Darién National Park | Playa del Muerto | Utría National Park | Ensenada de Utria | Manta | Salaverry | Paracas | Pingüino de Humboldt National Reserve | Valparaiso

  • 31 Oct 2027
  • 13 Nights
Fly Cruise From:
Was £9655pp Now: £9268pp
REF: SCENIC801L311027-1
Fly Cruise From:
Was £23888pp Now: £22932pp

Panama City | Darién National Park | Playa del Muerto | Utría National Park | Ensenada de Utria | Manta | Salaverry | Paracas | Pingüino de Humboldt National Reserve | Valparaiso | Niebla | Puerto Montt | Castro | Puerto Edén | PIO X Glacier | Punta Arenas | Chilean Fjords | Cape Horn | Buenos Aires | Ushuaia

  • 31 Oct 2027
  • 25 Nights
Fly Cruise From:
Was £23888pp Now: £22932pp
REF: SCENIC802L311027-1
Cruise From:
Was £8025pp Now: £7623pp

Baltra Island | Punta Suarez | Gardner Bay | Floreana Island | Punta Cormorant | Elizabeth Bay | Urbina Bay | Vincente Roca Point | Punta Espinoza | Daphne Major | South Plaza Island | Dragon Hill | Puerto Ayora | Baltra Island

  • 31 Oct 2027
  • 7 Nights
Cruise From:
Was £8025pp Now: £7623pp
REF: CELEBFL07G060-311027

Finest Collection

Holiday prices from:
£5699pp

Exhilarating South America with Iguazu Falls

Rio de Janeiro | Ilhabela | Balneário de Camboriú | Montevideo | Buenos Aires

  • 01 Nov 2027
  • 16 Nights
Holiday prices from:
£5699pp
REF: CRYSTALCSE-007-271104-2
Luxury hotel stays in Rio, Iguazu and Buenos Aires
Experience the awe of nature's power and beauty as you stand before the breath taking Iguazu Falls, one of the world's most spectacular natural wonders.
Fly Cruise From:
Was £8640pp Now: £8294pp

Valparaiso | Puerto Chacabuco | Chilean Fjords | Punta Arenas | Chilean Fjords | Garibaldi Fjord | Ushuaia

  • 01 Nov 2027
  • 12 Nights
Fly Cruise From:
Was £8640pp Now: £8294pp
REF: VIKINGXPO271101
Fly Cruise From:
Was £9914pp Now: £9517pp

Rio de Janeiro | Buzios | Abraao Beach | Parati | Ilhabela | São Francisco do Sul | Punta del Este | Montevideo | Buenos Aires

  • 03 Nov 2027
  • 11 Nights
Fly Cruise From:
Was £9914pp Now: £9517pp
REF: SCENIC601L031127-1
Fly Cruise From:
Was £28063pp Now: £26940pp

Rio de Janeiro | Buzios | Abraao Beach | Parati | Ilhabela | São Francisco do Sul | Punta del Este | Montevideo | Buenos Aires | Montevideo | Punta Piramides | Isla Pinguino | Punta Arenas | Ainsworth Bay | Tuckers Islets | Condor Glacier | Chilean Fjords | Cape Horn | Buenos Aires | Ushuaia

  • 03 Nov 2027
  • 27 Nights
Fly Cruise From:
Was £28063pp Now: £26940pp
REF: SCENIC602L031127-1
Cruise From:
£8740pp

Valparaiso | Quemchi | Caleta Tortel | PIO X Glacier | El Brujo Glacier | Estero las Montanas | Tuckers Islets | Alberto de Agostini National Park | Garibaldi Glacier | Cape Horn | Puerto Williams | Ushuaia

  • 03 Nov 2027
  • 14 Nights
Cruise From:
£8740pp
REF: PONANTLY031127
Cruise From:
Was £11797pp Now: £10499pp

Buenos Aires | Ushuaia | Antarctic Experience | Ushuaia | Buenos Aires | Ushuaia

  • 04 Nov 2027
  • 11 Nights
Cruise From:
Was £11797pp Now: £10499pp
REF: SBNP761
Fly Cruise From:
Was £21932pp Now: £21054pp

Lima | Machu Picchu | Cuzco | Machu Picchu | Cuzco | Santiago | Valparaiso | Santiago | Niebla | Puerto Montt | Castro | Puerto Edén | PIO X Glacier | Punta Arenas | Chilean Fjords | Cape Horn | Buenos Aires | Ushuaia

  • 04 Nov 2027
  • 21 Nights
Fly Cruise From:
Was £21932pp Now: £21054pp
REF: SCENICOLL2041127-1
Cruise From:
Was £2910pp Now: £2764pp

Rio de Janeiro | Ilhabela | Balneário de Camboriú | Montevideo | Buenos Aires

  • 04 Nov 2027
  • 7 Nights
Cruise From:
Was £2910pp Now: £2764pp
REF: CRYSTALCSE-007-271104
Cruise From:
Was £9200pp Now: £8740pp

Rio de Janeiro | Ilhabela | Balneário de Camboriú | Montevideo | Buenos Aires | Punta del Este | Puerto Madryn | Port Stanley | Ushuaia | Punta Arenas | Chilean Fjords | Laguna San Rafael National Park | Puerto Chacabuco | Castro | Puerto Montt | Valparaiso

  • 04 Nov 2027
  • 25 Nights
Cruise From:
Was £9200pp Now: £8740pp
REF: CRYSTALCSE-C25-271104
Fly Cruise From:
Was £8490pp Now: £8150pp

Valparaiso | Puerto Chacabuco | Chilean Fjords | Punta Arenas | Chilean Fjords | Garibaldi Fjord | Ushuaia

  • 05 Nov 2027
  • 12 Nights
Fly Cruise From:
Was £8490pp Now: £8150pp
REF: VIKINGXOC271105
Fly Cruise From:
Was £8690pp Now: £8342pp

Civitavecchia | Livorno | Monte-Carlo | Marseille | Sète | Barcelona | Málaga | Casablanca | Mindelo | Recife | Rio de Janeiro | Montevideo | Buenos Aires

  • 06 Nov 2027
  • 28 Nights
Fly Cruise From:
Was £8690pp Now: £8342pp
REF: VIKINGOJU271106A

Cruise & Stay

Holiday prices from:
£9299pp

Buenos Aires to Valparaiso with 5* Hotel Stay

Buenos Aires | Punta del Este | Puerto Madryn | Port Stanley | Ushuaia | Punta Arenas | Chilean Fjords | Laguna San Rafael National Park | Puerto Chacabuco | Castro | Puerto Montt | Valparaiso

  • 07 Nov 2027
  • 22 Nights
Holiday prices from:
£9299pp
REF: CRYSTALCSE-018-271111-2
Three-night 5* hotel stay in Buenos Aires
Experience the heart of Buenos Aires in a private day tour with a local guide
18-night ultra-luxury all-inclusive cruise
Flights and select private overseas transfers
Cruise From:
Was £8264pp Now: £7850pp

Baltra Island | Rabida Island | Puerto Egas | Elizabeth Bay | Tagus Cove | Bartolome Island | Sullivan Bay | Daphne Major | North Seymour Island | Las Bachas | Punta Pitt | Puerto Baquerizo Moreno | Puerto Ayora | Baltra Island

  • 07 Nov 2027
  • 7 Nights
Cruise From:
Was £8264pp Now: £7850pp
REF: CELEBFL07G059-071127
Cruise From:
£22900pp

Ushuaia | Antarctic Peninsula | Ushuaia

  • 08 Nov 2027
  • 12 Nights
Cruise From:
£22900pp
REF: PONANTCC081127

Prices are subject to change and availability. Prices may vary depending on the airport selected. Promotions are only applicable to select cabin grades, please call for details.

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UK Cruise Awards 2026 Partnership Achievement Award
UK Cruise Awards 2026 Partnership Achievement Award
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