Luxury South America Cruises

Luxury cruises in South America are all about the experience. Book one of the cruise deals below and you will have the opportunity to trek through wildlife-rich jungles, marvel at thundering waterfalls, visit ancient Incan ruins, and much more. Depending on the type of cruise you book, you may also get the chance to experience something truly unique, exclusively packaged up with luxury hotel stays and one-of-a-kind tours.

Find Out More About Cruising in South America

Showing 30 out of 1078 cruises
Per Person
Total Price
Cruise From:
£3780pp

Puntarenas | Bahía Drake | Manuel Antonio National Park | Cocos Island | Playa Mantas | Curú Wildlife Refuge | Cedros Island | Puntarenas

  • 11 Jan 2028
  • 7 Nights
Cruise From:
£3780pp
REF: PONANTEE110128
Cruise From:
Was £55000pp Now: £52250pp

Fort Lauderdale | Cozumel | Belize City | Santo Tomás de Castilla | Roatán Island | Puerto Limón | Cartagena | Fuerte Amador | Cartagena | Fuerte Amador | Manta | Guayaquil | Salaverry | Callao | Hangaroa | Adamstown | Fakarava | Rangiroa | Huahine | Papeete | Moorea | Raiatea | Bora-Bora | Pago Pago | Suva | Lautoka | Port Vila | Lifou Island | Nouméa | Pine Island | Bay of Islands | Auckland | Napier | Wellington | Melbourne | Portland | Adelaide | Kangaroo Island | Albany | Fremantle | Geraldton | Bali | Celukan Bawang | Puerto Princesa | Boracay Island | Manila | Nha Trang | Ho Chi Minh City | Singapore | Port Klang | Georgetown | Phuket | Port Blair | Hambantota | Colombo | Cochin | New Mangalore | Goa | Mumbai (ex Bombay) | Khasab | Abu Dhabi | Dubai | Fujairah | Muscat | Salalah | Jeddah | 'Aqaba | Luxor | Alexandria | Soúda | Katakolon | Siracuse | Valletta | Tunis | Trapani | Lipari | Sorrento | Civitavecchia | Barcelona | Alicante | Motril | Ponta Delgada | Horta | Kings Wharf | Fort Lauderdale

  • 11 Jan 2028
  • 150 Nights
Cruise From:
Was £55000pp Now: £52250pp
REF: CRYSTALCSY-W150-280111
Cruise From:
Was £53000pp Now: £50350pp

Fort Lauderdale | Cozumel | Belize City | Santo Tomás de Castilla | Roatán Island | Puerto Limón | Cartagena | Fuerte Amador | Cartagena | Fuerte Amador | Manta | Guayaquil | Salaverry | Callao | Hangaroa | Adamstown | Fakarava | Rangiroa | Huahine | Papeete | Moorea | Raiatea | Bora-Bora | Pago Pago | Suva | Lautoka | Port Vila | Lifou Island | Nouméa | Pine Island | Bay of Islands | Auckland | Napier | Wellington | Melbourne | Portland | Adelaide | Kangaroo Island | Albany | Fremantle | Geraldton | Bali | Celukan Bawang | Puerto Princesa | Boracay Island | Manila | Nha Trang | Ho Chi Minh City | Singapore | Port Klang | Georgetown | Phuket | Port Blair | Hambantota | Colombo | Cochin | New Mangalore | Goa | Mumbai (ex Bombay) | Khasab | Abu Dhabi | Dubai | Fujairah | Muscat | Salalah | Jeddah | 'Aqaba | Luxor | Alexandria | Soúda | Katakolon | Siracuse | Valletta | Tunis | Trapani | Lipari | Sorrento | Civitavecchia | Barcelona

  • 11 Jan 2028
  • 136 Nights
Cruise From:
Was £53000pp Now: £50350pp
REF: CRYSTALCSY-W136-280111
Cruise From:
Was £34900pp Now: £33155pp

Fort Lauderdale | Cozumel | Belize City | Santo Tomás de Castilla | Roatán Island | Puerto Limón | Cartagena | Fuerte Amador | Cartagena | Fuerte Amador | Manta | Guayaquil | Salaverry | Callao | Hangaroa | Adamstown | Fakarava | Rangiroa | Huahine | Papeete | Moorea | Raiatea | Bora-Bora | Pago Pago | Suva | Lautoka | Port Vila | Lifou Island | Nouméa | Pine Island | Bay of Islands | Auckland | Napier | Wellington | Melbourne | Portland | Adelaide | Kangaroo Island | Albany | Fremantle | Geraldton | Bali | Celukan Bawang | Puerto Princesa | Boracay Island | Manila | Nha Trang | Ho Chi Minh City | Singapore

  • 11 Jan 2028
  • 85 Nights
Cruise From:
Was £34900pp Now: £33155pp
REF: CRYSTALCSY-G85-280111
Cruise From:
Was £9519pp Now: £9043pp

Fort Lauderdale | Cozumel | Belize City | Santo Tomás de Castilla | Roatán Island | Puerto Limón | Cartagena | Fuerte Amador | Cartagena | Fuerte Amador | Manta | Guayaquil | Salaverry | Callao | Hangaroa | Adamstown | Fakarava | Rangiroa | Huahine | Papeete

  • 11 Jan 2028
  • 33 Nights
Cruise From:
Was £9519pp Now: £9043pp
REF: CRYSTALCSY-C33-280111
Cruise From:
Was £6184pp Now: £5874pp

Fort Lauderdale | Cozumel | Belize City | Santo Tomás de Castilla | Roatán Island | Puerto Limón | Cartagena | Fuerte Amador | Cartagena | Fuerte Amador | Manta | Guayaquil | Salaverry | Callao

  • 11 Jan 2028
  • 18 Nights
Cruise From:
Was £6184pp Now: £5874pp
REF: CRYSTALCSY-018-280111
Cruise From:
Was £14560pp Now: £13832pp

Puerto Williams | Antarctic Sound | Antarctic Peninsula | South Shetland Islands | Puerto Williams

  • 11 Jan 2028
  • 10 Nights
Cruise From:
Was £14560pp Now: £13832pp
REF: SILVERE4280111010
Cruise From:
£4920pp

Colón | Portobelo | San Blas Islands | Balboa (Panama City) | Quepos (Puerto Quepos) | Puntarenas

  • 12 Jan 2028
  • 7 Nights
Cruise From:
£4920pp
REF: PONANTEG120128
Fly Cruise From:
Was £9829pp Now: £9435pp

Bridgetown | Port Elizabeth | Mayreau Island | Kralendijk | Willemstad | Oranjestad | Santa Marta | Cartagena | San Blas Islands | Panama City

  • 13 Jan 2028
  • 11 Nights
Fly Cruise From:
Was £9829pp Now: £9435pp
REF: EMERALDE02C130128-2
Fly Cruise From:
Was £15507pp Now: £14886pp

Bridgetown | Port Elizabeth | Mayreau Island | Kralendijk | Willemstad | Oranjestad | Santa Marta | Cartagena | San Blas Islands | Panama City | Pearl Islands | Darién National Park | Playa del Muerto | Cébaco Island | Golfito | Quepos (Puerto Quepos) | Tortuga Island | Puerto Caldera

  • 13 Jan 2028
  • 18 Nights
Fly Cruise From:
Was £15507pp Now: £14886pp
REF: EMERALD2C02130128-2
Cruise From:
£11850pp

Ushuaia | Antarctic Peninsula | Ushuaia

  • 13 Jan 2028
  • 10 Nights
Cruise From:
£11850pp
REF: PONANTLY130128

Finest Collection

Holiday prices from:
£9199pp

A Journey South with Machu Picchu Discovery

Miami | Cozumel | Puerto Limón | Colón | Manta | Callao

  • 14 Jan 2028
  • 19 Nights
Holiday prices from:
£9199pp
REF: SILVERRA280115012-2
Experience the 'Lost City of the Incas'
Tours included in Cuzco and Lima
5* hotel stays in Miami, Cuzco & Lima

Finest Collection

Holiday prices from:
£10599pp

Crossing Continents and Cultures Cruise with Beauty of the Amazon Land Tour

Miami | Cozumel | Puerto Limón | Colón | Manta | Callao

  • 14 Jan 2028
  • 19 Nights
Holiday prices from:
£10599pp
REF: SILVERRA280115012-3
Three-night stay at Inkaterra Reserva Amazónica, Tambopata Province, Madre de Dios to explore the beauty of the Amazon
Cruise From:
Was £2439pp Now: £2341pp

Fuerte Amador | Manta | Callao | Pisco | Coquimbo | Valparaiso

  • 14 Jan 2028
  • 10 Nights
Cruise From:
Was £2439pp Now: £2341pp
REF: AZQS280114-010
Cruise From:
Was £24297pp Now: £21624pp

Buenos Aires | Ushuaia | Antarctic Experience | South Georgia Experience | Port Stanley | Falkland Islands | Buenos Aires | Ushuaia

  • 15 Jan 2028
  • 21 Nights
Cruise From:
Was £24297pp Now: £21624pp
REF: SBNP812
Fly Cruise From:
Was £31086pp Now: £29842pp

Buenos Aires | Ushuaia | Falkland Islands | South Georgia Island | Antarctic Peninsula | Ushuaia | Buenos Aires | Ushuaia

  • 15 Jan 2028
  • 19 Nights
Fly Cruise From:
Was £31086pp Now: £29842pp
REF: SCENIC201S150128-1
Cruise From:
Was £10800pp Now: £10260pp

San Cristóbal Island | Roca León Dormido | El Barranco | Darwin Bay | Sullivan Bay | North Seymour Island | Punta Moreno | Mangle Point | Los Gemelos | Puerto Ayora | Punta Suarez | Gardner Bay | Cerro Brujo | San Cristóbal Island

  • 15 Jan 2028
  • 7 Nights
Cruise From:
Was £10800pp Now: £10260pp
REF: SILVEROR280115007
Fly Cruise From:
Was £12990pp Now: £12470pp

Ushuaia | Antarctic Experience | Antarctica | Antarctic Experience | Antarctica | Ushuaia

  • 15 Jan 2028
  • 11 Nights
Fly Cruise From:
Was £12990pp Now: £12470pp
REF: VIKINGXOC280115T
Cruise From:
Was £6650pp Now: £6317pp

Miami | Cozumel | Puerto Limón | Colón | Manta | Callao

  • 15 Jan 2028
  • 12 Nights
Cruise From:
Was £6650pp Now: £6317pp
REF: SILVERRA280115012
Cruise From:
Was £13860pp Now: £13167pp

Puerto Williams | Antarctic Sound | Antarctic Peninsula | South Shetland Islands | King George Island

  • 15 Jan 2028
  • 9 Nights
Cruise From:
Was £13860pp Now: £13167pp
REF: SILVERWI280115009
Cruise From:
Was £6200pp Now: £5890pp

Cartagena | Panama City | Cartagena | Panama City | Manta | Callao | Valparaiso

  • 15 Jan 2028
  • 14 Nights
Cruise From:
Was £6200pp Now: £5890pp
REF: SILVERSS280115014
Cruise From:
Was £7085pp Now: £6730pp

Baltra Island | Rabida Island | Puerto Egas | Elizabeth Bay | Tagus Cove | Bartolome Island | Sullivan Bay | Daphne Major | North Seymour Island | Las Bachas | Punta Pitt | Puerto Baquerizo Moreno | Puerto Ayora | Baltra Island

  • 16 Jan 2028
  • 7 Nights
Cruise From:
Was £7085pp Now: £6730pp
REF: CELEBFL07G061-160128
Fly Cruise From:
Was £3799pp Now: £3590pp

Panama City | Cartagena | Willemstad | Oranjestad | Montego Bay | Georgetown | Miami

  • 16 Jan 2028
  • 10 Nights
Fly Cruise From:
Was £3799pp Now: £3590pp
REF: OCEANIAMNA280116
Cruise From:
Was £15397pp Now: £13703pp

Buenos Aires | Ushuaia | Antarctic Experience | Ushuaia | Buenos Aires | Ushuaia

  • 17 Jan 2028
  • 13 Nights
Cruise From:
Was £15397pp Now: £13703pp
REF: SBNV811
Fly Cruise From:
Was £20467pp Now: £19648pp

Buenos Aires | Ushuaia | Antarctic Peninsula | Ushuaia | Buenos Aires | Ushuaia

  • 18 Jan 2028
  • 12 Nights
Fly Cruise From:
Was £20467pp Now: £19648pp
REF: SCENIC101S180128-1
Cruise From:
Was £69319pp Now: £65506pp

Miami | Cartagena | Puerto Limón | Puerto Quetzal | Corinto | Cabo San Lucas | Los Angeles | Kahului-Maui | Nawiliwili | Honolulu | Hilo | Uturoa | Huahine | Papeete | Moorea | Papeete | Bora-Bora | Pago Pago | Vava'u | Lautoka | Port Vila | Nouméa | Sydney | Brisbane | Airlie Beach | Cairns | Thursday Island | Darwin | Kupang | Benoa | Jakarta | Singapore | Puerto Princesa | Coron Island | Manila | Salomague | Hualien | Keelung (Chilung) | Ishigaki | Kagoshima | Nagasaki | Busan | Beppu | Kochi | Osaka | Tokyo | Shimizu | Kobe | Hiroshima | Miyazaki | Naha | Kaohsiung | Hong Kong | Hanoi | Ho Chi Minh City | Kâmpóng Saôm | Koh Kood | Bangkok | Ko Samui | Singapore | Phuket | Hambantota | Male | Mumbai (ex Bombay) | Dubai | Doha | Abu Dhabi | Salalah | Jeddah | 'Aqaba | Sharm El Sheikh | Safaga | Heraklion (Iraklion) | Istanbul | Piraeus | Gythio | Katakolon | Messina | Salerno | Civitavecchia | Livorno | Villefranche-sur-Mer | Saint-Tropez | Sète | Palamós | Barcelona | Málaga | Portimão | Lisbon | Ponta Delgada | Halifax | New York

  • 18 Jan 2028
  • 181 Nights
Cruise From:
Was £69319pp Now: £65506pp
REF: OCEANIAARL280118L
Cruise From:
Was £9040pp Now: £8588pp

Fort Lauderdale | Road Town | Pointe-à-Pitre | Castries | Scarborough | Santarém | Boca da Valeria | Manaus | Parintins | Alter do Chão | Iles du Salut | Bridgetown | Roseau | Gustavia | Fort Lauderdale

  • 18 Jan 2028
  • 25 Nights
Cruise From:
Was £9040pp Now: £8588pp
REF: CRYSTALCSE-025-280118
Cruise From:
£1680pp

Puntarenas | Cabo San Lucas

  • 18 Jan 2028
  • 7 Nights
Cruise From:
£1680pp
REF: PONANTEE180128
Cruise From:
£3349pp

Callao | Hangaroa | Pitcairn Island | Fakarava | Moorea | Papeete | Moorea | Papeete

  • 19 Jan 2028
  • 16 Nights
Cruise From:
£3349pp
REF: AZON280119-016
Cruise From:
£5629pp

Callao | Hangaroa | Pitcairn Island | Fakarava | Moorea | Papeete | Moorea | Papeete | Bora-Bora | Russel | Auckland

  • 19 Jan 2028
  • 27 Nights
Cruise From:
£5629pp
REF: AZON280119-026

Prices are subject to change and availability. Prices may vary depending on the airport selected. Promotions are only applicable to select cabin grades, please call for details.

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