Luxury South America Cruises

Luxury cruises in South America are all about the experience. Book one of the cruise deals below and you will have the opportunity to trek through wildlife-rich jungles, marvel at thundering waterfalls, visit ancient Incan ruins, and much more. Depending on the type of cruise you book, you may also get the chance to experience something truly unique, exclusively packaged up with luxury hotel stays and one-of-a-kind tours.

Find Out More About Cruising in South America

Showing 30 out of 1077 cruises
Per Person
Total Price
Cruise From:
Was £16297pp Now: £14504pp

Buenos Aires | Ushuaia | Antarctic Experience | Buenos Aires | Ushuaia

  • 10 Jan 2027
  • 13 Nights
Cruise From:
Was £16297pp Now: £14504pp
REF: SBNP710
Cruise From:
Was £9119pp Now: £8663pp

Baltra Island | Punta Suarez | Gardner Bay | Floreana Island | Punta Cormorant | Elizabeth Bay | Urbina Bay | Vincente Roca Point | Punta Espinoza | Daphne Major | South Plaza Island | Dragon Hill | Puerto Ayora | Baltra Island

  • 10 Jan 2027
  • 7 Nights
Cruise From:
Was £9119pp Now: £8663pp
REF: CELEBFL07G060-100127
Fly Cruise From:
Was £74254pp Now: £70541pp

Miami | Cozumel | Costa Maya | Harvest Caye | Roatán Island | Georgetown | Ocho Rios | Puerto Limón | Cartagena | Panama City | Cartagena | Panama City | Puntarenas | Acajutla | Puerto Quetzal | Puerto Vallarta | Cabo San Lucas | Los Angeles | Honolulu | Kahului-Maui | Hilo | Bora-Bora | Papeete | Moorea | Papeete | Moorea | Huahine | Uturoa | Bora-Bora | Pago Pago | Apia | Suva | Lautoka | Mystery Island (Inyeug) | Lifou Island | Nouméa | Sydney | Townsville | Cairns | Cooktown | Darwin | Komodo Island | Benoa | Surabaya | Semarang | Singapore | Port Klang | Georgetown | Phuket | Colombo | Male | Cochin | Mangalore | Mormugao | Mumbai (ex Bombay) | Muscat | Dubai | Doha | Abu Dhabi | Salalah | Jeddah | Safaga | 'Aqaba | Haifa | Limassol | Rhodes | Kusadasi | Piraeus | Sorrento | Civitavecchia

  • 11 Jan 2027
  • 127 Nights
Fly Cruise From:
Was £74254pp Now: £70541pp
REF: REGENTSPL270111F
Fly Cruise From:
Was £81559pp Now: £77481pp

Miami | Cozumel | Costa Maya | Harvest Caye | Roatán Island | Georgetown | Ocho Rios | Puerto Limón | Cartagena | Panama City | Cartagena | Panama City | Puntarenas | Acajutla | Puerto Quetzal | Puerto Vallarta | Cabo San Lucas | Los Angeles | Honolulu | Kahului-Maui | Hilo | Bora-Bora | Papeete | Moorea | Papeete | Moorea | Huahine | Uturoa | Bora-Bora | Pago Pago | Apia | Suva | Lautoka | Mystery Island (Inyeug) | Lifou Island | Nouméa | Sydney | Townsville | Cairns | Cooktown | Darwin | Komodo Island | Benoa | Surabaya | Semarang | Singapore | Port Klang | Georgetown | Phuket | Colombo | Male | Cochin | Mangalore | Mormugao | Mumbai (ex Bombay) | Muscat | Dubai | Doha | Abu Dhabi | Salalah | Jeddah | Safaga | 'Aqaba | Haifa | Limassol | Rhodes | Kusadasi | Piraeus | Sorrento | Civitavecchia | Tarragona | Alicante | Málaga | Casablanca | Halifax | New York

  • 11 Jan 2027
  • 141 Nights
Fly Cruise From:
Was £81559pp Now: £77481pp
REF: REGENTSPL270111G
Fly Cruise From:
Was £12094pp Now: £9533pp

Miami | Cozumel | Costa Maya | Harvest Caye | Roatán Island | Georgetown | Ocho Rios | Puerto Limón | Cartagena | Panama City | Cartagena | Panama City

  • 12 Jan 2027
  • 14 Nights
Fly Cruise From:
Was £12094pp Now: £9533pp
REF: REGENTSPL270112
Fly Cruise From:
Was £27879pp Now: £19178pp

Miami | Cozumel | Costa Maya | Harvest Caye | Roatán Island | Georgetown | Ocho Rios | Puerto Limón | Cartagena | Panama City | Cartagena | Panama City | Puntarenas | Acajutla | Puerto Quetzal | Puerto Vallarta | Cabo San Lucas | Los Angeles | Honolulu | Kahului-Maui | Hilo | Bora-Bora | Papeete | Moorea | Papeete

  • 12 Jan 2027
  • 42 Nights
Fly Cruise From:
Was £27879pp Now: £19178pp
REF: REGENTSPL270112A
Cruise From:
Was £21969pp Now: £21090pp

Miami | Saint John Island | Charlotte Amalie | Philipsburg | Charlestown | Saint John's | Saint Pierre | Port Elizabeth | Saint George's | Bridgetown | Scarborough | Isle Royale | Belem | Recife | Salvador de Bahia | Buzios | Rio de Janeiro | Parati | Ilhabela | São Paulo | Montevideo | Buenos Aires | Montevideo | Punta del Este | Port Stanley | Ushuaia | Punta Arenas | Chilean Fjords | Puerto Chacabuco | Puerto Montt | San Antonio | Coquimbo | Iquique | Arica | Pisco | Callao | Fuerte Amador | Puerto Limón | San Andrés Island | Cozumel | Miami

  • 14 Jan 2027
  • 74 Nights
Cruise From:
Was £21969pp Now: £21090pp
REF: AZJR270114-074
Cruise From:
£8639pp

Miami | Saint John Island | Charlotte Amalie | Philipsburg | Charlestown | Saint John's | Saint Pierre | Port Elizabeth | Saint George's | Bridgetown | Scarborough | Isle Royale | Belem | Recife | Salvador de Bahia | Buzios | Rio de Janeiro | Parati | Ilhabela | São Paulo | Montevideo | Buenos Aires

  • 14 Jan 2027
  • 34 Nights
Cruise From:
£8639pp
REF: AZJR270114-034
Fly Cruise From:
Was £6784pp Now: £6444pp

Los Angeles | Cabo San Lucas | La Paz | Mazatlán | Manzanillo | Puerto Vallarta | Los Angeles

  • 14 Jan 2027
  • 10 Nights
Fly Cruise From:
Was £6784pp Now: £6444pp
REF: REGENTGRA270114
Fly Cruise From:
Was £13190pp Now: £12662pp

Ushuaia | Antarctic Experience | Antarctica | Antarctic Experience | Antarctica | Ushuaia

  • 14 Jan 2027
  • 11 Nights
Fly Cruise From:
Was £13190pp Now: £12662pp
REF: VIKINGXPO270114T
Cruise From:
£9753pp

Colón | Fuerte San Lorenzo | San Blas Islands | Pearl Islands | Darién National Park | Coiba Island | Bahía Drake | Curú Wildlife Refuge | Puntarenas

  • 14 Jan 2027
  • 10 Nights
Cruise From:
£9753pp
REF: PONANTEE140127
Fly Cruise From:
Was £3989pp Now: £3299pp

Panama City | Cartagena | Santa Marta | Oranjestad | Willemstad | Falmouth | Georgetown | Miami

  • 15 Jan 2027
  • 10 Nights
Fly Cruise From:
Was £3989pp Now: £3299pp
REF: OCEANIAMNA270115
Cruise From:
Was £8552pp Now: £8124pp

Fort Lauderdale | Gustavia | Fort-de-France | Kingstown | Scarborough | Santarém | Boca da Valeria | Manaus | Parintins | Alter do Chão | Iles du Salut | Bridgetown | Saint John's | Great Harbour | Fort Lauderdale

  • 15 Jan 2027
  • 25 Nights
Cruise From:
Was £8552pp Now: £8124pp
REF: CRYSTALCSY-025-270115
Cruise From:
Was £4740pp Now: £4503pp

Fort Lauderdale | Gustavia | Fort-de-France | Kingstown | Scarborough | Santarém | Boca da Valeria | Manaus

  • 15 Jan 2027
  • 12 Nights
Cruise From:
Was £4740pp Now: £4503pp
REF: CRYSTALCSY-S12-270115
Cruise From:
Was £20500pp Now: £19475pp

King George Island | Antarctic Sound | Antarctic Peninsula | South Shetland Islands | Puerto Williams

  • 15 Jan 2027
  • 9 Nights
Cruise From:
Was £20500pp Now: £19475pp
REF: SILVERWI270115009
Cruise From:
£5030pp

Colón | San Blas Islands | Portobelo | Darién National Park | Golfito | Puntarenas

  • 15 Jan 2027
  • 7 Nights
Cruise From:
£5030pp
REF: PONANTER150127
Fly Cruise From:
Was £19330pp Now: £17096pp

Buenos Aires | Ushuaia | Antarctic Peninsula | Ushuaia | Buenos Aires | Ushuaia

  • 16 Jan 2027
  • 12 Nights
Fly Cruise From:
Was £19330pp Now: £17096pp
REF: SCENIC101S160127-1
Cruise From:
Was £11800pp Now: £11210pp

San Cristóbal Island | Roca León Dormido | El Barranco | Darwin Bay | Sullivan Bay | North Seymour Island | Punta Moreno | Mangle Point | Los Gemelos | Puerto Ayora | Punta Suarez | Gardner Bay | Cerro Brujo | San Cristóbal Island

  • 16 Jan 2027
  • 7 Nights
Cruise From:
Was £11800pp Now: £11210pp
REF: SILVEROR270116007
Cruise From:
Was £9805pp Now: £9314pp

Baltra Island | Rabida Island | Puerto Egas | Elizabeth Bay | Tagus Cove | Bartolome Island | Sullivan Bay | Daphne Major | North Seymour Island | Las Bachas | Punta Pitt | Puerto Baquerizo Moreno | Puerto Ayora | Baltra Island

  • 17 Jan 2027
  • 7 Nights
Cruise From:
Was £9805pp Now: £9314pp
REF: CELEBFL07G059-170127
Cruise From:
£22620pp

Ushuaia | Antarctic Peninsula | Ushuaia

  • 17 Jan 2027
  • 10 Nights
Cruise From:
£22620pp
REF: PONANTAU170127
Cruise From:
Was £10298pp Now: £9165pp

Callao | General San Martin | Iquique | Hangaroa | Nuku Hiva Island | Hiva Oa Island | Fakarava | Avatiu | Papeete

  • 17 Jan 2027
  • 23 Nights
Cruise From:
Was £10298pp Now: £9165pp
REF: SBN6713
Fly Cruise From:
Was £26801pp Now: £25728pp

Rio de Janeiro | Iguazú Falls | Buenos Aires | Iguazú Falls | Buenos Aires | Ushuaia | Antarctic Peninsula | Ushuaia | Buenos Aires | Ushuaia

  • 18 Jan 2027
  • 20 Nights
Fly Cruise From:
Was £26801pp Now: £25728pp
REF: SCENICOSA1180127-1
Fly Cruise From:
Was £12990pp Now: £12470pp

Ushuaia | Antarctic Experience | Antarctica | Antarctic Experience | Antarctica | Ushuaia

  • 18 Jan 2027
  • 11 Nights
Fly Cruise From:
Was £12990pp Now: £12470pp
REF: VIKINGXOC270118T
Cruise From:
Was £21800pp Now: £20710pp

Bridgetown | Macapa | Parintins | Manaus | Boca de Valeria | Macapa | Boca de Valeria | Recife | Salvador de Bahia | Rio de Janeiro

  • 18 Jan 2027
  • 20 Nights
Cruise From:
Was £21800pp Now: £20710pp
REF: SILVERSN270118020
Cruise From:
Was £14997pp Now: £13347pp

Buenos Aires | Ushuaia | Antarctic Experience | Buenos Aires | Ushuaia

  • 19 Jan 2027
  • 11 Nights
Cruise From:
Was £14997pp Now: £13347pp
REF: SBNV711

Finest Collection

Holiday prices from:
£10599pp

Nights Of Samba & Tango with 5* Rio de Janeiro, Iguazu Falls and Buenos Aires stays

Rio de Janeiro | Buzios | Ilha Grande | Ilhabela | São Francisco do Sul | Porto Belo | Rio Grande | Montevideo | Buenos Aires

  • 19 Jan 2027
  • 19 Nights
Holiday prices from:
£10599pp
REF: REGENTMAR270122-2
Tours included in Rio de Janeiro & Iguazu Falls!
5* hotel stays in Rio de Janeiro, Buenos Aires and Iguazu
11-night luxury cruise from Rio de Janeiro to Brazil
Premium Economy flights included
Fly Cruise From:
Was £5359pp Now: £5198pp

Fort Lauderdale | Grand Turk Island | Bridgetown | Fortaleza | Salvador de Bahia | Buzios | Rio de Janeiro

  • 22 Jan 2027
  • 17 Nights
Fly Cruise From:
Was £5359pp Now: £5198pp
REF: CUNARDH704
Fly Cruise From:
Was £12169pp Now: £11803pp

Fort Lauderdale | Grand Turk Island | Bridgetown | Fortaleza | Salvador de Bahia | Buzios | Rio de Janeiro | Santos | Montevideo | Buenos Aires | Puerto Madryn | Ushuaia | Cape Horn | Punta Arenas | PIO X Glacier | Puerto Montt | San Antonio

  • 22 Jan 2027
  • 37 Nights
Fly Cruise From:
Was £12169pp Now: £11803pp
REF: CUNARDH704A
Fly Cruise From:
Was £18099pp Now: £17556pp

Fort Lauderdale | Grand Turk Island | Bridgetown | Fortaleza | Salvador de Bahia | Buzios | Rio de Janeiro | Santos | Montevideo | Buenos Aires | Puerto Madryn | Ushuaia | Cape Horn | Punta Arenas | PIO X Glacier | Puerto Montt | San Antonio | Coquimbo | Arica | Callao | Manta | Fuerte Amador | Aruba | Fort Lauderdale

  • 22 Jan 2027
  • 56 Nights
Fly Cruise From:
Was £18099pp Now: £17556pp
REF: CUNARDH704B
Cruise From:
Was £15897pp Now: £14148pp

Buenos Aires | Ushuaia | Antarctic Experience | Buenos Aires | Ushuaia

  • 22 Jan 2027
  • 11 Nights
Cruise From:
Was £15897pp Now: £14148pp
REF: SBNP711

Prices are subject to change and availability. Prices may vary depending on the airport selected. Promotions are only applicable to select cabin grades, please call for details.

Our Award-Winning Service


UK Cruise Awards 2026 Partnership Achievement Award
UK Cruise Awards 2026 Partnership Achievement Award
Luxury Cruise Agency of the Year 2025
Luxury Cruise Agency of the Year 2025
TTG Top 20 Luxury Travel Agents 2025
TTG Top 20 Luxury Travel Agents 2025
Best Workplaces in Travel 2024
Best Workplaces in Travel 2024
TTG Luxury Cruise Agency Of The Year 2024
TTG Luxury Cruise Agency Of The Year 2024
Best Use Of Content 2023
Best Use Of Content 2023
Best Specialist Cruise Agent 2023
Best Specialist Cruise Agent 2023
UK Cruise Awards Winners 2023
UK Cruise Awards Winners 2023
Travel Weekly Large Cruise Agency of the Year 2023
Travel Weekly Large Cruise Agency of the Year 2023
Best Luxury Travel Agent 2022
Best Luxury Travel Agent 2022
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