Luxury Central America Cruises

Situated between North and South America, Central America is a small but captivating stretch of land home to a number of distinctive, culturally-rich and naturally beautiful nations to uncover on a luxury cruise getaway with some of the world's finest SixStarCruises™

Find Out More About Cruising to Central America

Showing 30 out of 492 cruises
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Was £2459pp Now: £2360pp

Peru & Central America: Lima, Panama City & Puerto Limon

Callao | Fuerte Amador | Puerto Limón | San Andrés Island | Cozumel | Miami

  • 18 Mar 2027
  • 11 Nights
Up to $450 onboard spend
Cruise From:
Was £2459pp Now: £2360pp
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REF: AZJR270318-011
Fly Cruise From:
Was £2665pp Now: £2531pp

7 Night Key West, Mexico & Cayman

Port Canaveral | Key West | Georgetown | Cozumel | Port Canaveral

  • 20 Mar 2027
  • 7 Nights
Fly Cruise From:
Was £2665pp Now: £2531pp
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REF: CELEBAX07W681-200327
Fly Cruise From:
Was £16611pp Now: £15946pp

Ultimate South America to the Caribbean through the Panama Canal

Valparaiso | Pingüino de Humboldt National Reserve | Paracas | Salaverry | Manta | Utría National Park | Ensenada de Utria | Darién National Park | Playa del Muerto | Panama City | San Blas Islands | Cartagena | Cabo de la Vela | Willemstad | Tobago Cays | Mayreau Island | Soufrière | Bridgetown

  • 21 Mar 2027
  • 24 Nights
Fly Cruise From:
Was £16611pp Now: £15946pp
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REF: SCENIC132C210327-2
Fly Cruise From:
Was £8986pp Now: £8626pp

Ancient Kingdoms and Natural Treasures: Chile to Panama

Valparaiso | Pingüino de Humboldt National Reserve | Paracas | Salaverry | Manta | Utría National Park | Ensenada de Utria | Darién National Park | Playa del Muerto | Panama City

  • 21 Mar 2027
  • 13 Nights
Fly Cruise From:
Was £8986pp Now: £8626pp
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REF: SCENIC801L210327-2
Fly Cruise From:
Was £2382pp Now: £2262pp

7 Night Grand Cayman, Mexico & Bahamas

Fort Lauderdale | Bimini Island | Nassau | Cozumel | Georgetown | Fort Lauderdale

  • 21 Mar 2027
  • 7 Nights
Fly Cruise From:
Was £2382pp Now: £2262pp
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REF: CELEBBY07W714-210327
Cruise From:
£1840pp

Ocean Voyage: Cabo San Lucas - Puntarenas

Cabo San Lucas | Puntarenas

  • 22 Mar 2027
  • 7 Nights
Cruise From:
£1840pp
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REF: PONANTEE220327
Fly Cruise From:
Was £5852pp Now: £5559pp

7 Night Bahamas, Mexico & Cayman

Miami | Nassau | Georgetown | Cozumel | Costa Maya | Miami

  • 28 Mar 2027
  • 7 Nights
Fly Cruise From:
Was £5852pp Now: £5559pp
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REF: CELEBXC07E474-280327
Cruise From:
£8390pp

Secrets of Central America

Puntarenas | Curú Wildlife Refuge | Bahía Drake | Coiba Island | Darién National Park | Pearl Islands | San Blas Islands | Fuerte San Lorenzo | Colón

  • 29 Mar 2027
  • 10 Nights
Cruise From:
£8390pp
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REF: PONANTEE290327
Fly Cruise From:
Was £7529pp Now: £5348pp

Carnival Of Caribbean Colors

Panama City | Cartagena | Santa Marta | Oranjestad | Willemstad | Kralendijk | Saint George's | Castries | Gustavia | Tortola | Miami

  • 31 Mar 2027
  • 14 Nights
Book now with a 7.5% low deposit* - Ends 8th July
Sale now on - Save up to 50%!
Fly Cruise From:
Was £7529pp Now: £5348pp
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REF: REGENTGRA270331
Fly Cruise From:
Was £9990pp Now: £9590pp

Panama Canal & the Americas

Valparaiso | Iquique | Callao | Fuerte Amador | Port Antonio | Inagua | San Salvador Island | New York

  • 01 Apr 2027
  • 19 Nights
Receive a FREE Silver Spirits Drinks Package on ALL Ocean and Expedition voyages
Fly Cruise From:
Was £9990pp Now: £9590pp
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REF: VIKINGXOC270401
Cruise From:
Was £24159pp Now: £23192pp

Hong Kong to London Grand Voyage

Hong Kong | Keelung (Chilung) | Ishigaki | Naha | Shanghai | Dalian | Beijing | Seoul | Yeosu | Busan | Fukuoka | Kitakyushu | Hiroshima | Beppu | Kochi | Kobe | Shimizu | Tokyo | Oarai | Miyako | Kodiak | Juneau | Icy Strait Point | Ketchikan | Nanaimo | Vancouver | Seattle | Victoria | Astoria | San Francisco | San Diego | Cabo San Lucas | Acapulco | Puerto Quetzal | Acajutla | Puntarenas | Cartagena | Miami | New York | Newport | Boston | Halifax | Saint-John's | Cork | Plymouth | Le Havre | Tilbury

  • 02 Apr 2027
  • 87 Nights
Included in your Grand Voyage: Complimentary Airfare | Shore Excursion Credit | Upgrade Beverage package | WiFi for Two Devices | Weekly Laundry Service
Cruise From:
Was £24159pp Now: £23192pp
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REF: AZQS270402-088
Fly Cruise From:
Was £8745pp Now: £8395pp

Pristine islands of the Caribbean & the Panama Canal

Panama City | San Blas Islands | Cartagena | Cabo de la Vela | Willemstad | Tobago Cays | Mayreau Island | Soufrière | Bridgetown

  • 03 Apr 2027
  • 11 Nights
Fly Cruise From:
Was £8745pp Now: £8395pp
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REF: SCENIC131C030427-2
Fly Cruise From:
Was £3431pp Now: £3259pp

7 Night Key West, Mexico & Cayman

Port Canaveral | Key West | Georgetown | Cozumel | Port Canaveral

  • 03 Apr 2027
  • 7 Nights
Fly Cruise From:
Was £3431pp Now: £3259pp
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REF: CELEBAX07W681-030427
Cruise From:
Was £9750pp Now: £9262pp

A Grand Journey through Balmy Shores & Enchanting Nature to Panama’s Wonders

San Juan (Puerto Rico) | Gustavia | Little Bay | Basseterre | Key West | Miami | Ocho Rios | Willemstad | Oranjestad | Santa Marta | Cartagena | Panama City | Cartagena | Panama City

  • 05 Apr 2027
  • 17 Nights
Save up to 25% PLUS up to £2,600 Explora Credit
Cruise From:
Was £9750pp Now: £9262pp
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REF: EXPLORAEL20270405SJUAMD
Cruise From:
£5990pp

Panama, Colombia & Caribbean Islands

Colón | San Blas Islands | Cartagena | Santa Marta | Bonaire | Mayreau Island | Pigeon Island | Soufrière | Îles des Saintes | Fort-de-France

  • 08 Apr 2027
  • 10 Nights
Cruise From:
£5990pp
View cruise Enquire Enquire
REF: PONANTEE080427
Cruise From:
Was £1036pp Now: £984pp

7 Night Grand Cayman, Mexico & Bahamas

Fort Lauderdale | Nassau | Cozumel | Georgetown | Fort Lauderdale

  • 11 Apr 2027
  • 7 Nights

Interest free Monthly Payments from JUST £93pp

Cruise From:
Was £1036pp Now: £984pp
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REF: CELEBBY07W678-110427
Cruise From:
Was £5610pp Now: £5329pp

A Journey through Enchanting Nature & the Marvels of the Panama Canal

Miami | Ocho Rios | Willemstad | Oranjestad | Santa Marta | Cartagena | Panama City | Cartagena | Panama City

  • 12 Apr 2027
  • 10 Nights
Save up to 25% PLUS up to £2,600 Explora Credit
Cruise From:
Was £5610pp Now: £5329pp
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REF: EXPLORAEL20270412MIAAMD
Cruise From:
Was £12440pp Now: £11818pp

An Extended Journey from Majestic Horizons to Mayan Gems

Miami | Ocho Rios | Willemstad | Oranjestad | Santa Marta | Cartagena | Panama City | Cartagena | Panama City | Acajutla | Puerto Quetzal | Puerto Madero | Huatulco (Santa María Huatulco) | Puerto Vallarta | Los Angeles

  • 12 Apr 2027
  • 21 Nights
Save up to 25% PLUS up to £2,600 Explora Credit
Cruise From:
Was £12440pp Now: £11818pp
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REF: EXPLORAEL20270412MIALAX
Cruise From:
Was £16668pp Now: £14834pp

46-Day World Cruise: South Pacific & Panama Canal

Brisbane | Norfolk Island | Nouméa | Mystery Island (Inyeug) | Lautoka | Suva | Savusavu | Apia | Honolulu | Kailua-Kona | Long Beach | Puerto Vallarta | Huatulco (Santa María Huatulco) | Puerto Chiapas | Puerto Quetzal | Puntarenas | Cartagena | Miami

  • 15 Apr 2027
  • 46 Nights
Receive up to $1,000 onboard spend per couple - Offer ends 7th July
Cruise From:
Was £16668pp Now: £14834pp
View cruise Enquire Enquire
REF: SBN6728A
Cruise From:
Was £1465pp Now: £1391pp

7 Night Key West, Mexico & Cayman

Port Canaveral | Key West | Ocho Rios | Georgetown | Cozumel | Port Canaveral

  • 17 Apr 2027
  • 7 Nights

Interest free Monthly Payments from JUST £136pp

Cruise From:
Was £1465pp Now: £1391pp
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REF: CELEBAX07W681-170427

Cruise & Stay

5* Panama City Stay with A Journey of Mayan Discovery & Mexican Exploration

Holiday prices from:
£6199pp

5* Panama City Stay with A Journey of Mayan Discovery & Mexican Exploration

Panama City | Acajutla | Puerto Quetzal | Puerto Madero | Huatulco (Santa María Huatulco) | Puerto Vallarta | Los Angeles

  • 20 Apr 2027
  • 14 Nights
  • FREE 5* hotel stay in Panama City
  • FREE private tour of Panama City & Panama Canal
  • EXCLUSIVE offer to SixStarCruises
Holiday prices from:
£6199pp
View cruise
Cruise From:
Was £5480pp Now: £5206pp

A Journey of Mayan Discovery & Mexican Exploration

Panama City | Acajutla | Puerto Quetzal | Puerto Madero | Huatulco (Santa María Huatulco) | Puerto Vallarta | Los Angeles

  • 22 Apr 2027
  • 11 Nights
Save up to 25% PLUS up to £2,600 Explora Credit
Cruise From:
Was £5480pp Now: £5206pp
View cruise Enquire Enquire
REF: EXPLORAEL20270422AMDLAX
Cruise From:
Was £10320pp Now: £9804pp

An Extended Journey of Ancient Mysteries & Pacific Coastal Wonders

Panama City | Acajutla | Puerto Quetzal | Puerto Madero | Huatulco (Santa María Huatulco) | Puerto Vallarta | Los Angeles | San Diego | San Francisco | Victoria | Vancouver

  • 22 Apr 2027
  • 18 Nights
Save up to 25% PLUS up to £2,600 Explora Credit
Cruise From:
Was £10320pp Now: £9804pp
View cruise Enquire Enquire
REF: EXPLORAEL20270422AMDVAN
Cruise From:
Was £7848pp Now: £6984pp

27-Day World Cruise: Hawaii & Panama Canal

Honolulu | Kailua-Kona | Long Beach | Puerto Vallarta | Huatulco (Santa María Huatulco) | Puerto Chiapas | Puerto Quetzal | Puntarenas | Cartagena | Miami

  • 03 May 2027
  • 27 Nights
Cruise From:
Was £7848pp Now: £6984pp
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REF: SBN6728C

Cruise & Stay

5* Los Angeles & Miami Stays with 6* Panama Canal Crossing Cruise

Holiday prices from:
£8599pp

5* Los Angeles & Miami Stays with 6* Panama Canal Crossing Cruise

Long Beach | Puerto Vallarta | Huatulco (Santa María Huatulco) | Puerto Chiapas | Puerto Quetzal | Puntarenas | Cartagena | Miami

  • 09 May 2027
  • 23 Nights
  • Direct flights included!
  • 5* hotel stays in Los Angeles & Miami
  • 19-night ultra-luxury all-inclusive cruise
Holiday prices from:
£8599pp
View cruise
Cruise From:
Was £6698pp Now: £5961pp

19-Day World Cruise: Panama Canal Crossing

Long Beach | Puerto Vallarta | Huatulco (Santa María Huatulco) | Puerto Chiapas | Puerto Quetzal | Puntarenas | Cartagena | Miami

  • 11 May 2027
  • 19 Nights
Receive up to $1,000 onboard spend per couple - Offer ends 7th July
Cruise From:
Was £6698pp Now: £5961pp
View cruise Enquire Enquire
REF: SBN6731
Cruise From:
Was £9328pp Now: £8301pp

31-Day Panama Canal & Atlantic Passage

Long Beach | Puerto Vallarta | Huatulco (Santa María Huatulco) | Puerto Chiapas | Puerto Quetzal | Puntarenas | Cartagena | Miami | Funchal | Lisbon

  • 11 May 2027
  • 31 Nights
Cruise From:
Was £9328pp Now: £8301pp
View cruise Enquire Enquire
REF: SBN6731A
Fly Cruise From:
Was £3264pp Now: £3100pp

7 Night Grand Cayman & Mexico Cruise

Miami | Georgetown | Cozumel | Costa Maya | Coco Cay | Miami

  • 22 May 2027
  • 7 Nights
Fly Cruise From:
Was £3264pp Now: £3100pp
View cruise Enquire Enquire
REF: CELEBBY07W891-220527
Cruise From:
Was £4569pp Now: £4386pp

Panama Canal & Latin America Cruise: Mexico, Costa Rica & Colombia

San Diego | Cabo San Lucas | Acapulco | Puerto Quetzal | Acajutla | Puntarenas | Cartagena | Miami

  • 24 May 2027
  • 17 Nights
Up to $1,000 onboard spend
Cruise From:
Was £4569pp Now: £4386pp
View cruise Enquire Enquire
REF: AZQS270524-017
Cruise From:
Was £8679pp Now: £8331pp

San Diego to London Grand Voyage

San Diego | Cabo San Lucas | Acapulco | Puerto Quetzal | Acajutla | Puntarenas | Cartagena | Miami | New York | Newport | Boston | Halifax | Saint-John's | Cork | Plymouth | Le Havre | Tilbury

  • 24 May 2027
  • 35 Nights
Included in your Grand Voyage: Complimentary Airfare | Shore Excursion Credit | Upgrade Beverage package | WiFi for Two Devices | Weekly Laundry Service
Cruise From:
Was £8679pp Now: £8331pp
View cruise Enquire Enquire
REF: AZQS270524-035

Prices are subject to change and availability. Prices may vary depending on the airport selected. Promotions are only applicable to select cabin grades, please call for details.

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