Luxury South America Cruises

Luxury cruises in South America are all about the experience. Book one of the cruise deals below and you will have the opportunity to trek through wildlife-rich jungles, marvel at thundering waterfalls, visit ancient Incan ruins, and much more. Depending on the type of cruise you book, you may also get the chance to experience something truly unique, exclusively packaged up with luxury hotel stays and one-of-a-kind tours.

Find Out More About Cruising in South America


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Antarctica, South Georgia & Falkland Islands
Buenos Aires | Falkland Islands | Falkland Islands | South Georgia Island | South Georgia Island | South Georgia Island | South Georgia Island | Antarctic Peninsula | Antarctic Peninsula | Antarctic Peninsula | Antarctic Peninsula | Antarctic Peninsula | Ushuaia | Buenos Aires | More...
27 Nov 2024
21 Nights
Atlantic Islands

Fly Cruise From
Was £26917pp
Now: £25840
pp
REF: SCENIC311S271124-1
Fort Lauderdale to San Juan
Fort Lauderdale, Florida | Saint Thomas | Road Town, Tortola | Marigot | Basseterre, Saint Kitts | San Juan (Puerto Rico)
27 Nov 2024
7 Nights
South America

Cruise Only From
Was £3050pp
Now: £2958
pp
REF: CRYSTALCSE-007-241127
Puerto Williams to Puerto Williams
Puerto Williams | Antarctic Sound | Antarctic Peninsula | Antarctic Peninsula | Antarctic Peninsula | South Shetland Islands | Puerto Williams | Puerto Williams
29 Nov 2024
10 Nights
Antarctica

Save £2400 per couple
Fly Cruise From
Was £12500pp
Now: £11875
pp
REF: SILVERE4241129010
San Cristóbal to San Cristóbal
San Cristóbal Island, Galápagos | Roca León Dormido | Bartolome Island | Santiago Island, Galápagos | Punta Vicente Roca, Isabela Island, Galápagos | Punta Espinoza, Fernandina Island, Galápagos | Elizabeth Bay, Isabela Island, Galápagos | Caleta Tagus | Champion Island, Galápagos | Post Office Bay, Floreana, Galápagos | Punta Cormorant, Floreana Island, Galápagos | Los Gemelos, Santa Cruz Island, Galápagos | Puerto Ayora, Isla Santa Cruz | Santa Cruz Island, Galápagos | More...
30 Nov 2024
7 Nights
Pacific

Save £2400 per couple
Fly Cruise From
Was £29900pp
Now: £28405
pp
REF: SILVEROR241130007
Panama Canal Voyage with Panama Stay
Miami, Florida | Oranjestad | Kralendijk | Willemstad | Cartagena | Fuerte Amador | Fuerte Amador
02 Dec 2024
15 Nights
Panama Canal

Hidden Gems Sale - $500 to spend on board | Book a Veranda or Suite to get unlimited Wi-Fi or a Premium Beverage Package
Two-night luxury hotel stay included when booking with SixStarCruises
HOLIDAY PRICES FROM
Was £3699pp
Now: £3389
pp
REF: AZJR10C013-031224-2

Cruise & Stay

South Georgia & Antarctic Odyssey
Ushuaia | Ushuaia | Antarctic Peninsula | Antarctic Peninsula | Antarctic Peninsula | Elephant Island, South Shetland Islands | South Georgia Island | South Georgia Island | South Georgia Island | South Georgia Island | South Georgia Island | Falkland Islands | Ushuaia
02 Dec 2024
20 Nights
Antarctica

Cruise Only From
Was £18253pp
Now: £17705
pp
REF: AURORAASG093S
11 Night Panama Canal & S Caribbean
Fort Lauderdale, Florida | Cartagena | Colón | Oranjestad | Kralendijk | Georgetown, Grand Cayman | Fort Lauderdale, Florida
02 Dec 2024
11 Nights
Panama Canal

Fly Cruise From
Was £2624pp
Now: £2109
pp
REF: CELEBBY11C017-021224
10-Night Ceo Loyalty Panama Canal Voyage
Miami, Florida | Oranjestad | Kralendijk | Willemstad | Cartagena | Fuerte Amador | Fuerte Amador
03 Dec 2024
10 Nights
Panama Canal

Hidden Gems Sale - $500 to spend on board | Book a Veranda or Suite to get unlimited Wi-Fi or a Premium Beverage Package
Two-night luxury hotel stay included when booking with SixStarCruises
Cruise Only From
Was £2662pp
Now: £1343
pp
REF: AZJR10C013-031224
Western Caribbean Bliss
Miami, Florida | Costa Maya | Harvest Caye | Santo Tomás de Castilla | Roatán Island | Puerto Limón | Colón | Cartagena | Cartagena
03 Dec 2024
10 Nights
Caribbean

FREE shore excursion credit, FREE gratuities, FREE Wi-Fi, FREE speciality dining and FREE Champagne, wine and more with lunch and dinner
Fly Cruise From
Was £2939pp
Now: £2792
pp
REF: OCEANIANAU241203
Caribbean Panorama
Miami, Florida | Costa Maya | Harvest Caye | Santo Tomás de Castilla | Roatán Island | Puerto Limón | Colón | Cartagena | Cartagena | Santa Marta | Oranjestad | Willemstad | Castries | Gustavia | More...
03 Dec 2024
20 Nights
Caribbean

FREE shore excursion credit, FREE gratuities, FREE Wi-Fi, FREE speciality dining and FREE Champagne, wine and more with lunch and dinner
Fly Cruise From
Was £4859pp
Now: £4531
pp
REF: OCEANIANAU241203A
12-Day Antarctica Exploration
Buenos Aires | Ushuaia | Antarctic Experience | Antarctic Experience | Antarctic Experience | Antarctic Experience | Antarctic Experience | Antarctic Experience | Antarctic Experience | Buenos Aires | Ushuaia
06 Dec 2024
13 Nights
Antarctica

Save up to 15%* - book today to avoid disappointment
Cruise Only From
Was £9858pp
Now: £9266
pp
REF: SBNV466
South America Kaleidoscope
Miami, Florida | Costa Maya | Harvest Caye | Roatán Island | Puerto Limón | Panama City | Panama City | Manta | Salaverry | Callao | Callao | Pisco | Coquimbo | San Antonio | More...
07 Dec 2024
50 Nights
South America

FREE shore excursion credit, FREE gratuities, FREE Wi-Fi, FREE speciality dining and FREE Champagne, wine and more with lunch and dinner
Fly Cruise From
Was £13949pp
Now: £13251
pp
REF: OCEANIAMNA241207B
Maya & Inca Discovery
Miami, Florida | Costa Maya | Harvest Caye | Roatán Island | Puerto Limón | Panama City | Panama City | Manta | Salaverry | Callao | Callao
07 Dec 2024
14 Nights
South America

FREE shore excursion credit, FREE gratuities, FREE Wi-Fi, FREE speciality dining and FREE Champagne, wine and more with lunch and dinner
Fly Cruise From
Was £5869pp
Now: £5575
pp
REF: OCEANIAMNA241207
Sunlit Strands & Icy Lands
Miami, Florida | Costa Maya | Harvest Caye | Roatán Island | Puerto Limón | Panama City | Panama City | Manta | Salaverry | Callao | Callao | Pisco | Coquimbo | San Antonio | More...
07 Dec 2024
38 Nights
World-wide

FREE shore excursion credit, FREE gratuities, FREE Wi-Fi, FREE speciality dining and FREE Champagne, wine and more with lunch and dinner
Fly Cruise From
Was £12469pp
Now: £11846
pp
REF: OCEANIAMNA241207A
Spirit of Antarctica
Ushuaia | Ushuaia | South Shetland Islands | Antarctic Peninsula | Antarctic Peninsula | Antarctic Peninsula | Antarctic Peninsula | Antarctic Peninsula | Ushuaia
08 Dec 2024
11 Nights
Antarctica

Cruise Only From
Was £12451pp
Now: £11154
pp
REF: AURORAANP171G
Puerto Williams to Puerto Williams
Puerto Williams | Antarctic Sound | Antarctic Peninsula | Antarctic Peninsula | Antarctic Peninsula | South Shetland Islands | Puerto Williams | Puerto Williams
08 Dec 2024
10 Nights
Antarctica

Save £2400 per couple
Fly Cruise From
Was £12900pp
Now: £12255
pp
REF: SILVERWI241208010
Puerto Williams to Puerto Williams
Puerto Williams | Antarctic Sound | Antarctic Peninsula | Antarctic Peninsula | Antarctic Peninsula | South Shetland Islands | Puerto Williams | Puerto Williams
09 Dec 2024
10 Nights
Antarctica

Save £2400 per couple
Fly Cruise From
Was £13100pp
Now: £12445
pp
REF: SILVERE4241209010
Tropical Holiday
Miami, Florida | Georgetown, Grand Cayman | Cartagena | Puntarenas | Corinto | Puerto Quetzal | Acapulco | Cabo San Lucas | Ensenada | Los Angeles, California
13 Dec 2024
16 Nights
Panama Canal

Ultimate All-Inclusive Cruise Fare now includes: Round-trip Economy flights, transfers between airport and ship PLUS Private Executive Chauffeur Credit*
Fly Cruise From
Was £11299pp
Now: £10734
pp
REF: REGENTGRA241213
Caribbean Chic
Cartagena | Santa Marta | Oranjestad | Willemstad | Castries | Gustavia | San Juan (Puerto Rico) | Puerto Plata | Miami, Florida
13 Dec 2024
10 Nights
Caribbean

FREE shore excursion credit, FREE gratuities, FREE Wi-Fi, FREE speciality dining and FREE Champagne, wine and more with lunch and dinner
Fly Cruise From
Was £3059pp
Now: £2906
pp
REF: OCEANIANAU241213
San Cristóbal to San Cristóbal
San Cristóbal Island, Galápagos | Roca León Dormido | Bartolome Island | Santiago Island, Galápagos | Punta Vicente Roca, Isabela Island, Galápagos | Punta Espinoza, Fernandina Island, Galápagos | Elizabeth Bay, Isabela Island, Galápagos | Caleta Tagus | Champion Island, Galápagos | Post Office Bay, Floreana, Galápagos | Punta Cormorant, Floreana Island, Galápagos | Los Gemelos, Santa Cruz Island, Galápagos | Puerto Ayora, Isla Santa Cruz | Santa Cruz Island, Galápagos | More...
14 Dec 2024
7 Nights
Pacific

Save £2400 per couple
Fly Cruise From
Was £20300pp
Now: £19285
pp
REF: SILVEROR241214007
20-Day Antarctica, South Georgia & Falkland
Buenos Aires | Ushuaia | New Island | West Point Island | Saunders Island | Carcass Island | Port Stanley | South Georgia Experience | South Georgia Experience | South Georgia Experience | Antarctic Experience | Antarctic Experience | Antarctic Experience | Antarctic Experience | More...
15 Dec 2024
21 Nights
Antarctica

Save up to 15%* - book today to avoid disappointment
Cruise Only From
Was £15553pp
Now: £14619
pp
REF: SBNP467
7 Night Galapagos Outer Loop Cruise
Baltra Island, Galápagos | Punta Suarez, Isla Española, Galápagos | Gardner Bay, Española Island, Galápagos | Floreana Island, Galapagos | Punta Cormorant, Floreana Island, Galápagos | Elizabeth Bay, Isabela Island, Galápagos | Urbina Bay, Isabella Island, Galapagos | Vincente Roca Point, Isabella Island, Galapagos | Punta Espinoza, Fernandina Island, Galápagos | Daphne Major, Galapagos | South Plaza Island, Galápagos | Dragon Hill, Santa Cruz Island, Galápagos | Puerto Ayora, Isla Santa Cruz | Baltra Island, Galápagos More...
15 Dec 2024
7 Nights
Pacific

Cruise Only From
Was £9785pp
Now: £8080
pp
REF: CELEBFL07G046-151224
Fort Lauderdale to Los Angeles
Fort Lauderdale, Florida | Cartagena | Cartagena | Panama City | Puntarenas | Cabo San Lucas | San Diego, California | Los Angeles, California
17 Dec 2024
18 Nights
Caribbean

Save £2400 per couple
Fly Cruise From
Was £33100pp
Now: £25365
pp
REF: SILVERSS241217018
Fort Lauderdale to Fuerte Amador
Fort Lauderdale, Florida | Cartagena | Cartagena | Panama City
17 Dec 2024
7 Nights
Caribbean

Save £2400 per couple
Cruise Only From
Was £5450pp
Now: £5177
pp
REF: SILVERSS241217S07
Falklands, South Georgia & Antarctic Peninsula
Ushuaia | Ushuaia | Antarctic Peninsula | Antarctic Peninsula | Antarctic Peninsula | Antarctic Peninsula | Antarctic Peninsula | South Georgia Island | South Georgia Island | South Georgia Island | South Georgia Island | Falkland Islands | Falkland Islands | Ushuaia More...
18 Dec 2024
20 Nights
Antarctica

Cruise Only From
Was £21722pp
Now: £21070
pp
REF: AURORAFSP006G

Explore South America on a Finest Collection voyage

Our Finest Collection cruise packages in South America offer tailor-made adventures exclusively for you. Your cruise is paired with a set of immersive land tours dedicated to helping you get right to the heart of the ports on your itinerary. What's more, after days spent hiking across glaciers or exploring iconic cities accompanied by a local tour guide, you can retire to a five-star hotel for a gourmet dinner and spot of well-earned relaxation. 

South America expedition cruises

If you want your South America cruise adventure to be even more unforgettable, embark on an expedition cruise and feel like a true explorer. Sailing to destinations like mysterious Easter Island, wild and rugged Chile, and the positively prehistoric Galapagos islands; once-in-a-lifetime experiences are guaranteed. Accompanied by a dedicated group of expedition experts - from marine biologists to professional adventurers - you willl live like an intrepid explorer and witness natural wonders most people can only dream of.

Book South America cruises with our Cruise Concierge team

If you would like to embark on an adventure you will never forget, call our Cruise Concierge team to book one of the itineraries below. And if you can't find exactly what you are looking for? Call us to build a completely bespoke cruise in South America that incorporates every port and experience you have been dreaming of.

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