Luxury South America Cruises

Luxury cruises in South America are all about the experience. Book one of the cruise deals below and you will have the opportunity to trek through wildlife-rich jungles, marvel at thundering waterfalls, visit ancient Incan ruins, and much more. Depending on the type of cruise you book, you may also get the chance to experience something truly unique, exclusively packaged up with luxury hotel stays and one-of-a-kind tours.

Find Out More About Cruising in South America


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11 Night Canal & S. Caribbean
Fort Lauderdale, Florida | Cartagena | Colón | Kralendijk | Oranjestad | Georgetown, Grand Cayman | Fort Lauderdale, Florida
17 Mar 2025
11 Nights
Panama Canal

Fly Cruise From
Was £6487pp
Now: £6162
pp
REF: CELEBBY11C021-170325
20-Day Easter & Pitcairn Islands: Marooned, Moai & Mutineers
San Antonio | Hangaroa, Easter Island | Hangaroa, Easter Island | Ducie Island | Henderson Island | Pitcairn Island | Fakarava | Toau Atoll | Anaa | Papeete, Tahiti
18 Mar 2025
20 Nights
Pacific

Save up to 15%* - book today to avoid disappointment
Cruise Only From
Was £11789pp
Now: £11081
pp
REF: SBNP521
37-Day Island Cultures From Easter Island To Melanesia
San Antonio | Hangaroa, Easter Island | Hangaroa, Easter Island | Ducie Island | Henderson Island | Pitcairn Island | Fakarava | Toau Atoll | Anaa | Papeete, Tahiti | Raiatea | Aitutaki | Apia | Vava'u | More...
18 Mar 2025
38 Nights
Australia & New Zealand

Save up to 15%* - book today to avoid disappointment
Cruise Only From
Was £26255pp
Now: £24679
pp
REF: SBNP521A
52-Day History, Culture & Isles Of Oceania
San Antonio | Hangaroa, Easter Island | Hangaroa, Easter Island | Ducie Island | Henderson Island | Pitcairn Island | Fakarava | Toau Atoll | Anaa | Papeete, Tahiti | Raiatea | Aitutaki | Apia | Vava'u | More...
18 Mar 2025
52 Nights
Australia & New Zealand

Save up to 15%* - book today to avoid disappointment
Cruise Only From
Was £34352pp
Now: £32290
pp
REF: SBNP521B
Ushuaia to Valparaiso
Ushuaia | Chilean Fjords | Montanas Fjord | Chilean Fjords | Chilean Fjords | Chilean Fjords | Caleta Tortel | Castro | Niebla | Valparaiso
19 Mar 2025
12 Nights
Antarctica

Save £2400 per couple
Cruise Only From
Was £5600pp
Now: £5320
pp
REF: SILVERE4250319S12
Bridgetown to Los Angeles, California
Bridgetown | Port Elizabeth, Bequia | Castries | Fort-de-France | Philipsburg | Saint John's | Gustavia | San Juan (Puerto Rico) | Grand Turk Island | Fort Lauderdale, Florida | Fort Lauderdale, Florida | Cartagena | Cartagena | Puntarenas | More...
21 Mar 2025
29 Nights
Caribbean

Save £2400 per couple
Fly Cruise From
Was £9600pp
Now: £9120
pp
REF: SILVERMO250321C29
San Cristóbal to San Cristóbal
San Cristóbal Island, Galápagos | Roca León Dormido | Bartolome Island | Santiago Island, Galápagos | Punta Vicente Roca, Isabela Island, Galápagos | Punta Espinoza, Fernandina Island, Galápagos | Elizabeth Bay, Isabela Island, Galápagos | Caleta Tagus | Champion Island, Galápagos | Post Office Bay, Floreana, Galápagos | Punta Cormorant, Floreana Island, Galápagos | Los Gemelos, Santa Cruz Island, Galápagos | Puerto Ayora, Isla Santa Cruz | Santa Cruz Island, Galápagos | More...
22 Mar 2025
7 Nights
Pacific

Save £2400 per couple
Fly Cruise From
Was £11200pp
Now: £10640
pp
REF: SILVEROR250322007
Rhythms of the Brazilian Coastline
Buenos Aires | Montevideo | Punta del Este | São Francisco do Sul | Pontal do Sul | Ilhabela | Parati | Ilha Grande | Buzios | Rio de Janeiro | Rio de Janeiro
22 Mar 2025
12 Nights
South America

Fly Cruise From
Was £12009pp
Now: £11528
pp
REF: SCENIC501L220325-2
San Cristóbal, Galapagos to San Cristóbal, Galapagos
San Cristóbal Island, Galápagos | Roca León Dormido | Bartolome Island | Santiago Island, Galápagos | Punta Vicente Roca, Isabela Island, Galápagos | Punta Espinoza, Fernandina Island, Galápagos | Elizabeth Bay, Isabela Island, Galápagos | Caleta Tagus | Champion Island, Galápagos | Post Office Bay, Floreana, Galápagos | Punta Cormorant, Floreana Island, Galápagos | Los Gemelos, Santa Cruz Island, Galápagos | Puerto Ayora, Isla Santa Cruz | Santa Cruz Island, Galápagos | More...
22 Mar 2025
14 Nights
South America

Save £2400 per couple
Fly Cruise From
Was £66100pp
Now: £21945
pp
REF: SILVEROR250322C14
Pearls Of The Panama Canal
Miami, Florida | Great Stirrup Cay | Costa Maya | Santo Tomás de Castilla | Belize City | Roatán Island | Puerto Limón | Panama City | Panama City | Panama City | Cartagena | Santa Marta | Oranjestad | Willemstad | More...
23 Mar 2025
20 Nights
Panama Canal

Bonus Savings Sale - Save up to 30%*
Your World Included - FREE gratuities, FREE gourmet speciality dining, FREE unlimited Wi-Fi and FREE soft drinks including speciality teas & coffees
Fly Cruise From
Was £5620pp
Now: £5339
pp
REF: OCEANIASIR250323A
Beautiful Brazil & Beyond
Buenos Aires | Buenos Aires | Montevideo | Punta del Este | Balneário de Camboriú | São Francisco do Sul | Santos | Parati | Ilha Grande | Buzios | Rio de Janeiro | Rio de Janeiro
24 Mar 2025
12 Nights
South America

Bonus Savings Sale - Save up to 30%*
Your World Included - FREE gratuities, FREE gourmet speciality dining, FREE unlimited Wi-Fi and FREE soft drinks including speciality teas & coffees
Fly Cruise From
Was £4752pp
Now: £4514
pp
REF: OCEANIAMNA250324
Verdant Atlantic Vistas
Buenos Aires | Buenos Aires | Montevideo | Punta del Este | Balneário de Camboriú | São Francisco do Sul | Santos | Parati | Ilha Grande | Buzios | Rio de Janeiro | Rio de Janeiro | Buzios | Salvador de Bahia | More...
24 Mar 2025
38 Nights
Atlantic Islands

Bonus Savings Sale - Save up to 30%*
Your World Included - FREE gratuities, FREE gourmet speciality dining, FREE unlimited Wi-Fi and FREE soft drinks including speciality teas & coffees
Fly Cruise From
Was £7881pp
Now: £7486
pp
REF: OCEANIAMNA250324B
Brilliant Brazil & Iberia
Buenos Aires | Buenos Aires | Montevideo | Punta del Este | Balneário de Camboriú | São Francisco do Sul | Santos | Parati | Ilha Grande | Buzios | Rio de Janeiro | Rio de Janeiro | Buzios | Salvador de Bahia | More...
24 Mar 2025
45 Nights
World-wide

Your World Included - FREE gratuities, FREE gourmet speciality dining, FREE unlimited Wi-Fi and FREE soft drinks including speciality teas & coffees
Fly Cruise From
Was £13419pp
Now: £12748
pp
REF: OCEANIAMNA250324C
Wild Antarctica featuring the Weddell Sea
Punta Arenas | Punta Arenas | Antarctic Peninsula | Antarctic Peninsula | Antarctic Peninsula | Antarctic Peninsula | Antarctic Peninsula | Ushuaia
24 Mar 2025
11 Nights
Antarctica

Cruise Only From
Was £8882pp
Now: £8615
pp
REF: AURORAANW009S
San Cristóbal to San Cristóbal
San Cristóbal Island, Galápagos | Roca León Dormido | El Barranco, Genovesa Island, Galápagos | Darwin Bay, Genovesa Island, Galápagos | Sullivan Bay, Santiago Island, Galápagos | North Seymour Island, Galapagos | Punta Moreno, Isabella Island, Galapagos | Mangle Point, Fernandina Island, Galápagos | Los Gemelos, Santa Cruz Island, Galápagos | Puerto Ayora, Isla Santa Cruz | Punta Suarez, Isla Española, Galápagos | Gardner Bay, Española Island, Galápagos | Cerro Brujo, San Cristóbal Island, Galápagos | San Cristóbal Island, Galápagos | More...
29 Mar 2025
7 Nights
Pacific

Save £2400 per couple
Fly Cruise From
Was £24100pp
Now: £22895
pp
REF: SILVEROR250329007
Remote Wonders of the Pacific and Easter Island's Legends - Valparaiso to Papeete
Valparaiso | San Juan Bautista (Robinson Crusoe Island) | Alejandro Selkirk Island | Hangaroa, Easter Island | Hangaroa, Easter Island | Pitcairn Island | Pitcairn Island | Nuku Hiva Island | Atuona, Hiva Oa | Tahuata Island | Hana Vave, Fatu Hiva Island | Rangiroa | Papeete, Tahiti
31 Mar 2025
23 Nights
Pacific

Limited time 10% savings included
Save £2400 per couple
Fly Cruise From
Was £14300pp
Now: £11087
pp
REF: SILVERE4250331023
Valparaiso to Lautoka
Valparaiso | San Juan Bautista (Robinson Crusoe Island) | Alejandro Selkirk Island | Hangaroa, Easter Island | Hangaroa, Easter Island | Pitcairn Island | Pitcairn Island | Nuku Hiva Island | Atuona, Hiva Oa | Tahuata Island | Hana Vave, Fatu Hiva Island | Rangiroa | Papeete, Tahiti | Papeete, Tahiti | More...
31 Mar 2025
50 Nights
Pacific

Save £2400 per couple
Fly Cruise From
Was £40400pp
Now: £38380
pp
REF: SILVERE4250331C49
Fort Lauderdale to Los Angeles
Fort Lauderdale, Florida | Cartagena | Cartagena | Puntarenas | Puerto Quetzal | Puerto Vallarta | Cabo San Lucas | Los Angeles, California
01 Apr 2025
18 Nights
Caribbean

$300 FREE to spend on-board - ONLY when booking with SixStarCruises
Save £2400 per couple
Fly Cruise From
Was £9200pp
Now: £7410
pp
REF: SILVERMO250401018
Captivating Panama Canal
Panama City | Panama City | Cartagena | Santa Marta | Oranjestad | Willemstad | Kralendijk | Port Antonio | Miami, Florida
02 Apr 2025
10 Nights
Panama Canal

Bonus Savings Sale - Save up to 30%*
Your World Included - FREE gratuities, FREE gourmet speciality dining, FREE unlimited Wi-Fi and FREE soft drinks including speciality teas & coffees
Fly Cruise From
Was £3971pp
Now: £3772
pp
REF: OCEANIASIR250402
A Grand Journey Bridging America, Azore Isles and Catalonia
Miami, Florida | Kings Wharf | Horta, Azores | Azores | Lisbon | Cartagena | Valencia | Barcelona
02 Apr 2025
16 Nights
Mediterranean

Enjoy a complimentary dinner at Anthology PLUS book with a low 10% deposit*
Cruise Only From
Was £5175pp
Now: £4916
pp
REF: EXPLORAEX20250402MIABCN
An Extended Journey Bridging America and the Med’s Ancient Greats
Miami, Florida | Kings Wharf | Horta, Azores | Azores | Lisbon | Cartagena | Valencia | Barcelona | Palma de Mallorca | Palermo | Valletta | Khania | Rhodes | Kusadasi | More...
02 Apr 2025
26 Nights
Mediterranean

Enjoy a complimentary dinner at Anthology PLUS book with a low 10% deposit*
Cruise Only From
Was £8885pp
Now: £8440
pp
REF: EXPLORAEX20250402MIAPIR
Wellness Retreat: Rio to Santa Cruz de Tenerife
Rio de Janeiro | Santa Cruz de Tenerife
03 Apr 2025
12 Nights
Transatlantic

Fly Cruise From
Was £6129pp
Now: £5883
pp
REF: SCENIC401R030425-1A
Crossing the Equator: Rio to the Spanish Riviera
Rio de Janeiro | Santa Cruz de Tenerife | Santa Cruz de La Palma | Funchal, Madeira | Funchal, Madeira | Porto Santo Island | Tangier | Málaga
03 Apr 2025
19 Nights
Mediterranean

Fly Cruise From
Was £9717pp
Now: £9328
pp
REF: SCENIC401R030425-1
San Cristóbal to San Cristóbal
San Cristóbal Island, Galápagos | Roca León Dormido | Bartolome Island | Santiago Island, Galápagos | Punta Vicente Roca, Isabela Island, Galápagos | Punta Espinoza, Fernandina Island, Galápagos | Elizabeth Bay, Isabela Island, Galápagos | Caleta Tagus | Champion Island, Galápagos | Post Office Bay, Floreana, Galápagos | Punta Cormorant, Floreana Island, Galápagos | Los Gemelos, Santa Cruz Island, Galápagos | Puerto Ayora, Isla Santa Cruz | Santa Cruz Island, Galápagos | More...
05 Apr 2025
7 Nights
Pacific

Save £2400 per couple
Fly Cruise From
Was £12600pp
Now: £11970
pp
REF: SILVEROR250405007
Icons Of Brazil & Iberia
Rio de Janeiro | Buzios | Salvador de Bahia | Maceió | Recife | Mindelo, São Vicente Island | Dakar | San Sebastian de la Gomera | Santa Cruz de Tenerife | Santa Cruz de La Palma | Funchal, Madeira | Casablanca | Gibraltar | Almería | More...
05 Apr 2025
26 Nights
Transatlantic

Bonus Savings Sale - Save up to 30%*
Your World Included - FREE gratuities, FREE gourmet speciality dining, FREE unlimited Wi-Fi and FREE soft drinks including speciality teas & coffees
Fly Cruise From
Was £5749pp
Now: £5461
pp
REF: OCEANIAMNA250405A

Explore South America on a Finest Collection voyage

Our Finest Collection cruise packages in South America offer tailor-made adventures exclusively for you. Your cruise is paired with a set of immersive land tours dedicated to helping you get right to the heart of the ports on your itinerary. What's more, after days spent hiking across glaciers or exploring iconic cities accompanied by a local tour guide, you can retire to a five-star hotel for a gourmet dinner and spot of well-earned relaxation. 

South America expedition cruises

If you want your South America cruise adventure to be even more unforgettable, embark on an expedition cruise and feel like a true explorer. Sailing to destinations like mysterious Easter Island, wild and rugged Chile, and the positively prehistoric Galapagos islands; once-in-a-lifetime experiences are guaranteed. Accompanied by a dedicated group of expedition experts - from marine biologists to professional adventurers - you willl live like an intrepid explorer and witness natural wonders most people can only dream of.

Book South America cruises with our Cruise Concierge team

If you would like to embark on an adventure you will never forget, call our Cruise Concierge team to book one of the itineraries below. And if you can't find exactly what you are looking for? Call us to build a completely bespoke cruise in South America that incorporates every port and experience you have been dreaming of.

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