Luxury South America Cruises

Luxury cruises in South America are all about the experience. Book one of the cruise deals below and you will have the opportunity to trek through wildlife-rich jungles, marvel at thundering waterfalls, visit ancient Incan ruins, and much more. Depending on the type of cruise you book, you may also get the chance to experience something truly unique, exclusively packaged up with luxury hotel stays and one-of-a-kind tours.

Find Out More About Cruising in South America

Showing 30 out of 926 cruises
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Fly Cruise From:
Was £21972pp Now: £21093pp

Antarctica & Iguazu Falls Delight - Cruise & Land Journey

Buenos Aires | Ushuaia | Antarctic Peninsula | Ushuaia | Buenos Aires | Ushuaia | Buenos Aires | Iguazú Falls

  • 26 Jan 2029
  • 16 Nights
Fly Cruise From:
Was £21972pp Now: £21093pp
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REF: SCENICOSI1260129-2
Cruise From:
Was £11070pp Now: £10516pp

San Cristóbal to San Cristóbal

San Cristóbal Island | Roca León Dormido | El Barranco | Darwin Bay | Sullivan Bay | North Seymour Island | Punta Moreno | Mangle Point | Los Gemelos | Puerto Ayora | Punta Suarez | Gardner Bay | Cerro Brujo | San Cristóbal Island

  • 27 Jan 2029
  • 7 Nights
Save up to 40% PLUS deposits from 15%*
Cruise From:
Was £11070pp Now: £10516pp
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REF: SILVEROR290127007
Fly Cruise From:
Was £24392pp Now: £23416pp

Vibrant Wonders of Peru & Antarctica - Cruise & Land Lourney

Lima | Machu Picchu | Cuzco | Machu Picchu | Cuzco | Buenos Aires | Ushuaia | Antarctic Peninsula | Ushuaia | Buenos Aires | Ushuaia

  • 28 Jan 2029
  • 21 Nights
Fly Cruise From:
Was £24392pp Now: £23416pp
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REF: SCENICOSL1280129-1
Cruise From:
Was £12960pp Now: £12312pp

Puerto Williams to King George Island

Puerto Williams | South Shetland Islands | Antarctic Peninsula | South Shetland Islands | King George Island

  • 29 Jan 2029
  • 9 Nights
Save up to 40% PLUS deposits from 15%*
Cruise From:
Was £12960pp Now: £12312pp
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REF: SILVERWI290129009
Fly Cruise From:
Was £6379pp Now: £6028pp

Azure Abcs & Panama Passage

Miami | Puerto Plata | Kralendijk | Willemstad | Oranjestad | Cartagena | Puerto Limón | Panama City | Puerto Limón | Panama City

  • 30 Jan 2029
  • 12 Nights
Choose between FREE Wine, Beer & Champagne by the glass with lunch and dinner OR shore excursion credit
Fly Cruise From:
Was £6379pp Now: £6028pp
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REF: OCEANIASON290130
Fly Cruise From:
Was £9879pp Now: £9335pp

Caribbean & Canal Crest

Miami | Puerto Plata | Kralendijk | Willemstad | Oranjestad | Cartagena | Puerto Limón | Panama City | Puerto Limón | Panama City | Oranjestad | Saint George's | Roseau | Basseterre | Tortola | Miami

  • 30 Jan 2029
  • 23 Nights
Choose between FREE Wine, Beer & Champagne by the glass with lunch and dinner OR shore excursion credit
Fly Cruise From:
Was £9879pp Now: £9335pp
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REF: OCEANIASON290130A
Fly Cruise From:
Was £9394pp Now: £9018pp

Costa Rica, Panama from the Atlantic to the Pacific via the Panama Canal

Puerto Caldera | Tortuga Island | Quepos (Puerto Quepos) | Golfito | Cébaco Island | Darién National Park | Playa del Muerto | Pearl Islands | Panama City | Bocas del Toro | Puerto Limón | San José

  • 31 Jan 2029
  • 12 Nights
Fly Cruise From:
Was £9394pp Now: £9018pp
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REF: EMERALDE03C310129-1
Fly Cruise From:
Was £12564pp Now: £11935pp

Fjords Of Fire And Ice

Buenos Aires | Punta del Este | Port Stanley | Ushuaia | Punta Arenas | Puerto Chacabuco | Puerto Montt | Valparaiso

  • 01 Feb 2029
  • 17 Nights
Fly Cruise From:
Was £12564pp Now: £11935pp
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REF: REGENTMAR290201
Fly Cruise From:
Was £16974pp Now: £16125pp

Patagonian Expedition

Buenos Aires | Punta del Este | Port Stanley | Ushuaia | Punta Arenas | Puerto Chacabuco | Puerto Montt | Valparaiso | Coquimbo | Iquique | Arica | Pisco | Callao

  • 01 Feb 2029
  • 25 Nights
Fly Cruise From:
Was £16974pp Now: £16125pp
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REF: REGENTMAR290201A
Fly Cruise From:
Was £38410pp Now: £36873pp

Ultimate Journey: South America, Antarctica & South Georgia

Lima | Machu Picchu | Cuzco | Machu Picchu | Cuzco | Buenos Aires | Ushuaia | Falkland Islands | South Georgia Island | Antarctic Peninsula | Ushuaia | Buenos Aires | Ushuaia | Buenos Aires | Iguazú Falls | Rio de Janeiro | Iguazú Falls | Rio de Janeiro

  • 02 Feb 2029
  • 37 Nights
Fly Cruise From:
Was £38410pp Now: £36873pp
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REF: SCENICOAL2020229-1
Fly Cruise From:
Was £32490pp Now: £31190pp

Southern Expedition: Antarctica & Machu Picchu - Cruise & Land Journey

Lima | Machu Picchu | Cuzco | Machu Picchu | Cuzco | Buenos Aires | Ushuaia | Falkland Islands | South Georgia Island | Antarctic Peninsula | Ushuaia | Buenos Aires | Ushuaia

  • 02 Feb 2029
  • 28 Nights
Fly Cruise From:
Was £32490pp Now: £31190pp
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REF: SCENICOSL2020229-1
Fly Cruise From:
Was £28496pp Now: £27356pp

Wonders of Machu Picchu, the Amazon & Antarctica - Cruise & Land Journey

Lima | Machu Picchu | Cuzco | Machu Picchu | Cuzco | Buenos Aires | Ushuaia | Antarctic Peninsula | Ushuaia | Buenos Aires | Ushuaia

  • 02 Feb 2029
  • 27 Nights
Fly Cruise From:
Was £28496pp Now: £27356pp
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REF: SCENICOSZ1020229-1
Cruise From:
Was £11070pp Now: £10516pp

San Cristóbal to San Cristóbal

San Cristóbal Island | Roca León Dormido | Bartolome Island | Santiago Island | Punta Vicente Roca | Punta Espinoza | Elizabeth Bay | Caleta Tagus | Champion Island | Post Office Bay | Punta Cormorant | Los Gemelos | Puerto Ayora | Santa Cruz Island | Isla Guy Fawkes | Dragon Hill | San Cristóbal Island

  • 03 Feb 2029
  • 7 Nights
Save up to 40% PLUS deposits from 15%*
Cruise From:
Was £11070pp Now: £10516pp
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REF: SILVEROR290203007
Cruise From:
Was £29970pp Now: £28471pp

King George Island to Puerto Williams

King George Island | Antarctic Peninsula | Antarctic Sound | Elephant Island | South Georgia Island | Puerto Williams

  • 04 Feb 2029
  • 15 Nights
Save up to 40% PLUS deposits from 15%*
Cruise From:
Was £29970pp Now: £28471pp
View cruise Enquire Enquire
REF: SILVEREV290204015
Fly Cruise From:
Was £21972pp Now: £21093pp

Antarctica & Iguazu Falls Delight - Cruise & Land Journey

Buenos Aires | Ushuaia | Antarctic Peninsula | Ushuaia | Buenos Aires | Ushuaia | Buenos Aires | Iguazú Falls

  • 06 Feb 2029
  • 16 Nights
Fly Cruise From:
Was £21972pp Now: £21093pp
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REF: SCENICOSI1060229-2
Fly Cruise From:
Was £9487pp Now: £9012pp

Tropical Transit

Miami | Georgetown | Cartagena | Puntarenas | Puerto Quetzal | Acapulco | Cabo San Lucas | Ensenada | Los Angeles

  • 07 Feb 2029
  • 16 Nights
Fly Cruise From:
Was £9487pp Now: £9012pp
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REF: REGENTPRT290207
Fly Cruise From:
Was £9444pp Now: £9066pp

Costa Rica, Panama from the Pacific to the Atlantic via the Panama Canal

San José | Puerto Limón | San José | Puerto Limón | Bocas del Toro | Panama City | Bocas del Toro | Panama City | Pearl Islands | Darién National Park | Playa del Muerto | Cébaco Island | Golfito | Quepos (Puerto Quepos) | Puerto Caldera | Curú Wildlife Refuge | Puerto Caldera

  • 10 Feb 2029
  • 12 Nights
Fly Cruise From:
Was £9444pp Now: £9066pp
View cruise Enquire Enquire
REF: EMERALDE03C100229-2
Cruise From:
Was £11070pp Now: £10516pp

San Cristóbal to San Cristóbal

San Cristóbal Island | Roca León Dormido | El Barranco | Darwin Bay | Sullivan Bay | North Seymour Island | Punta Moreno | Mangle Point | Los Gemelos | Puerto Ayora | Punta Suarez | Gardner Bay | Cerro Brujo | San Cristóbal Island

  • 10 Feb 2029
  • 7 Nights
Save up to 40% PLUS deposits from 15%*
Cruise From:
Was £11070pp Now: £10516pp
View cruise Enquire Enquire
REF: SILVEROR290210007
Fly Cruise From:
Was £33770pp Now: £32419pp

Antarctica, South Georgia, Argentina & Brazil - Cruise & Land Journey

Buenos Aires | Ushuaia | Falkland Islands | South Georgia Island | Antarctic Peninsula | Ushuaia | Buenos Aires | Ushuaia | Buenos Aires | Iguazú Falls | Rio de Janeiro | Iguazú Falls | Rio de Janeiro

  • 11 Feb 2029
  • 28 Nights
Fly Cruise From:
Was £33770pp Now: £32419pp
View cruise Enquire Enquire
REF: SCENICOSA2110229-2
Cruise From:
Was £14720pp Now: £13984pp

Puerto Williams to Puerto Williams

Puerto Williams | South Georgia Island | Elephant Island | Antarctic Peninsula | South Shetland Islands | Puerto Williams

  • 11 Feb 2029
  • 15 Nights
Save up to 40% PLUS deposits from 15%*
Cruise From:
Was £14720pp Now: £13984pp
View cruise Enquire Enquire
REF: SILVERE4290211015
Cruise From:
Was £12960pp Now: £12312pp

King George Island to Puerto Williams

King George Island | South Shetland Islands | Antarctic Peninsula | South Shetland Islands | Puerto Williams

  • 13 Feb 2029
  • 9 Nights
Save up to 40% PLUS deposits from 15%*
Cruise From:
Was £12960pp Now: £12312pp
View cruise Enquire Enquire
REF: SILVERWI290213009
Fly Cruise From:
Was £25698pp Now: £24670pp

Wonders of Machu Picchu, the Amazon & Antarctica - Cruise & Land Journey

Lima | Machu Picchu | Cuzco | Machu Picchu | Cuzco | Lima | Buenos Aires | Lima | Buenos Aires | Ushuaia | Antarctic Peninsula | Ushuaia | Buenos Aires | Ushuaia

  • 16 Feb 2029
  • 25 Nights
Fly Cruise From:
Was £25698pp Now: £24670pp
View cruise Enquire Enquire
REF: SCENICOSZ1160229-1
Fly Cruise From:
Was £36535pp Now: £35073pp

Ultimate Antarctica & the Fjords of Southern Chile

Buenos Aires | Ushuaia | Antarctic Peninsula | Ushuaia | Cape Horn | Pia Glacier | Garibaldi Glacier | Chilean Fjords | Aguila Glacier | Chilean Fjords | Condor Glacier | Tuckers Islets | Punta Arenas | Isla Pinguino | Punta Piramides | Montevideo | Buenos Aires

  • 17 Feb 2029
  • 28 Nights
Fly Cruise From:
Was £36535pp Now: £35073pp
View cruise Enquire Enquire
REF: SCENIC702L170229-2
Fly Cruise From:
Was £25667pp Now: £24640pp

Highlights of Antarctica, Argentina and Brazil - Cruise & Land Journey

Buenos Aires | Ushuaia | Antarctic Peninsula | Ushuaia | Buenos Aires | Ushuaia | Buenos Aires | Iguazú Falls | Rio de Janeiro | Iguazú Falls | Rio de Janeiro

  • 17 Feb 2029
  • 21 Nights
Fly Cruise From:
Was £25667pp Now: £24640pp
View cruise Enquire Enquire
REF: SCENICOSA1170229-2
Cruise From:
Was £11070pp Now: £10516pp

San Cristóbal to San Cristóbal

San Cristóbal Island | Roca León Dormido | Bartolome Island | Santiago Island | Punta Vicente Roca | Punta Espinoza | Elizabeth Bay | Caleta Tagus | Champion Island | Post Office Bay | Punta Cormorant | Los Gemelos | Puerto Ayora | Santa Cruz Island | Isla Guy Fawkes | Dragon Hill | San Cristóbal Island

  • 17 Feb 2029
  • 7 Nights
Save up to 40% PLUS deposits from 15%*
Cruise From:
Was £11070pp Now: £10516pp
View cruise Enquire Enquire
REF: SILVEROR290217007
Fly Cruise From:
Was £6512pp Now: £6186pp

The Poets' Passage

Valparaiso | Coquimbo | Iquique | Arica | Pisco | Callao

  • 18 Feb 2029
  • 8 Nights
Fly Cruise From:
Was £6512pp Now: £6186pp
View cruise Enquire Enquire
REF: REGENTMAR290218
Fly Cruise From:
Was £33454pp Now: £32115pp

Ultimate Journey: Patagonia, Argentina, Brazil & Antarctica - Cruise & Land Journey

Santiago | Torres del Paine National Park | Santiago | Torres del Paine National Park | El Calafate | Ushuaia | El Calafate | Antarctic Peninsula | Ushuaia | Buenos Aires | Ushuaia | Buenos Aires | Iguazú Falls | Rio de Janeiro | Iguazú Falls | Rio de Janeiro

  • 22 Feb 2029
  • 28 Nights
Fly Cruise From:
Was £33454pp Now: £32115pp
View cruise Enquire Enquire
REF: SCENICOPA1220229-1
Fly Cruise From:
Was £27534pp Now: £26432pp

Wonders of Patagonia & Antarctica - Cruise & Land Journey

Santiago | Torres del Paine National Park | Santiago | Torres del Paine National Park | El Calafate | Ushuaia | El Calafate | Antarctic Peninsula | Ushuaia | Buenos Aires | Ushuaia

  • 22 Feb 2029
  • 19 Nights
Fly Cruise From:
Was £27534pp Now: £26432pp
View cruise Enquire Enquire
REF: SCENICOSP1220229-1
Fly Cruise From:
Was £17533pp Now: £16831pp

Discover the Secrets of Costa Rica and Panama

Puerto Caldera | Tortuga Island | Quepos (Puerto Quepos) | Golfito | Cébaco Island | Darién National Park | Playa del Muerto | Pearl Islands | Panama City | San Blas Islands | Cartagena | Santa Marta | Oranjestad | Willemstad | Kralendijk | Mayreau Island | Port Elizabeth | Bridgetown

  • 22 Feb 2029
  • 18 Nights
Fly Cruise From:
Was £17533pp Now: £16831pp
View cruise Enquire Enquire
REF: EMERALD2C02220229-1
Cruise From:
Was £12375pp Now: £11756pp

Puerto Williams to King George Island

Puerto Williams | South Shetland Islands | Antarctic Peninsula | South Shetland Islands | King George Island

  • 22 Feb 2029
  • 9 Nights
Save up to 40% PLUS deposits from 15%*
Cruise From:
Was £12375pp Now: £11756pp
View cruise Enquire Enquire
REF: SILVERWI290222009

Prices are subject to change and availability. Prices may vary depending on the airport selected. Promotions are only applicable to select cabin grades, please call for details.

Explore South America on a Finest Collection voyage

Our Finest Collection cruise packages in South America offer tailor-made adventures exclusively for you. Your cruise is paired with a set of immersive land tours dedicated to helping you get right to the heart of the ports on your itinerary. What's more, after days spent hiking across glaciers or exploring iconic cities accompanied by a local tour guide, you can retire to a five-star hotel for a gourmet dinner and spot of well-earned relaxation. 

South America expedition cruises

If you want your South America cruise adventure to be even more unforgettable, embark on an expedition cruise and feel like a true explorer. Sailing to destinations like mysterious Easter Island, wild and rugged Chile, and the positively prehistoric Galapagos islands; once-in-a-lifetime experiences are guaranteed. Accompanied by a dedicated group of expedition experts - from marine biologists to professional adventurers - you willl live like an intrepid explorer and witness natural wonders most people can only dream of.

Book South America cruises with our Cruise Concierge team

If you would like to embark on an adventure you will never forget, call our Cruise Concierge team to book one of the itineraries below. And if you can't find exactly what you are looking for? Call us to build a completely bespoke cruise in South America that incorporates every port and experience you have been dreaming of.

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