Luxury South America Cruises

Luxury cruises in South America are all about the experience. Book one of the cruise deals below and you will have the opportunity to trek through wildlife-rich jungles, marvel at thundering waterfalls, visit ancient Incan ruins, and much more. Depending on the type of cruise you book, you may also get the chance to experience something truly unique, exclusively packaged up with luxury hotel stays and one-of-a-kind tours.

Find Out More About Cruising in South America

Showing 30 out of 926 cruises
Per Person
Total Price
List Grid

Range:

APPLY
Cruise From:
Was £9160pp Now: £8702pp

7 Night Galapagos Inner Loop Cruise

Baltra Island | Rabida Island | Puerto Egas | Elizabeth Bay | Tagus Cove | Bartolome Island | Sullivan Bay | Daphne Major | North Seymour Island | Las Bachas | Punta Pitt | Puerto Baquerizo Moreno | Puerto Ayora | Baltra Island

  • 11 Apr 2027
  • 7 Nights
Cruise From:
Was £9160pp Now: £8702pp
View cruise Enquire Enquire
REF: CELEBFL07G059-110427
Cruise From:
Was £6885pp Now: £6540pp

A Journey through Enchanting Nature & the Marvels of the Panama Canal

Miami | Ocho Rios | Willemstad | Oranjestad | Santa Marta | Cartagena | Panama City | Cartagena | Panama City

  • 12 Apr 2027
  • 10 Nights
Save up to 25% PLUS up to £2,600 Explora Credit - ENDS 28th July
Cruise From:
Was £6885pp Now: £6540pp
View cruise Enquire Enquire
REF: EXPLORAEL20270412MIAAMD
Cruise From:
Was £12440pp Now: £11818pp

An Extended Journey from Majestic Horizons to Mayan Gems

Miami | Ocho Rios | Willemstad | Oranjestad | Santa Marta | Cartagena | Panama City | Cartagena | Panama City | Acajutla | Puerto Quetzal | Puerto Madero | Huatulco (Santa María Huatulco) | Puerto Vallarta | Los Angeles

  • 12 Apr 2027
  • 21 Nights
Save up to 25% PLUS up to £2,600 Explora Credit - ENDS 28th July
Cruise From:
Was £12440pp Now: £11818pp
View cruise Enquire Enquire
REF: EXPLORAEL20270412MIALAX
Cruise From:
Was £13701pp Now: £12193pp

46-Day World Cruise: South Pacific & Panama Canal

Brisbane | Norfolk Island | Nouméa | Mystery Island (Inyeug) | Lautoka | Suva | Savusavu | Apia | Honolulu | Kailua-Kona | Long Beach | Puerto Vallarta | Huatulco (Santa María Huatulco) | Puerto Chiapas | Puerto Quetzal | Puntarenas | Cartagena | Miami

  • 15 Apr 2027
  • 46 Nights
Save up to 15% for a limited time only!
Cruise From:
Was £13701pp Now: £12193pp
View cruise Enquire Enquire
REF: SBN6728A
Cruise From:
Was £11259pp Now: £10696pp

San Cristóbal to San Cristóbal

San Cristóbal Island | Roca León Dormido | Bartolome Island | Santiago Island | Punta Vicente Roca | Punta Espinoza | Elizabeth Bay | Caleta Tagus | Champion Island | Post Office Bay | Punta Cormorant | Los Gemelos | Puerto Ayora | Santa Cruz Island | Isla Guy Fawkes | Dragon Hill | San Cristóbal Island

  • 17 Apr 2027
  • 7 Nights
Save up to 40% PLUS deposits from 15%*
Cruise From:
Was £11259pp Now: £10696pp
View cruise Enquire Enquire
REF: SILVEROR270417007
Cruise From:
Was £13387pp Now: £12717pp

7 Night Galapagos Outer Loop Cruise

Baltra Island | Punta Suarez | Gardner Bay | Floreana Island | Punta Cormorant | Elizabeth Bay | Urbina Bay | Vincente Roca Point | Punta Espinoza | Daphne Major | South Plaza Island | Dragon Hill | Puerto Ayora | Baltra Island

  • 18 Apr 2027
  • 7 Nights
Cruise From:
Was £13387pp Now: £12717pp
View cruise Enquire Enquire
REF: CELEBFL07G060-180427

Cruise & Stay

5* Panama City Stay with A Journey of Mayan Discovery & Mexican Exploration

Holiday prices from:
£6149pp

5* Panama City Stay with A Journey of Mayan Discovery & Mexican Exploration

Panama City | Acajutla | Puerto Quetzal | Puerto Madero | Huatulco (Santa María Huatulco) | Puerto Vallarta | Los Angeles

  • 20 Apr 2027
  • 14 Nights
  • 5* hotel stay in Panama City
  • private tour of Panama City & Panama Canal
Holiday prices from:
£6149pp
View cruise
Cruise From:
Was £5480pp Now: £5206pp

A Journey of Mayan Discovery & Mexican Exploration

Panama City | Acajutla | Puerto Quetzal | Puerto Madero | Huatulco (Santa María Huatulco) | Puerto Vallarta | Los Angeles

  • 22 Apr 2027
  • 11 Nights
Save up to 25% PLUS up to £2,600 Explora Credit - ENDS 28th July
Cruise From:
Was £5480pp Now: £5206pp
View cruise Enquire Enquire
REF: EXPLORAEL20270422AMDLAX
Cruise From:
Was £9183pp Now: £8723pp

7 Night Galapagos Inner Loop Cruise

Baltra Island | Rabida Island | Puerto Egas | Elizabeth Bay | Tagus Cove | Bartolome Island | Sullivan Bay | Daphne Major | North Seymour Island | Las Bachas | Punta Pitt | Puerto Baquerizo Moreno | Puerto Ayora | Baltra Island

  • 25 Apr 2027
  • 7 Nights
Cruise From:
Was £9183pp Now: £8723pp
View cruise Enquire Enquire
REF: CELEBFL07G059-250427
Cruise From:
Was £10325pp Now: £9808pp

7 Night Galapagos Outer Loop Cruise

Baltra Island | Punta Suarez | Gardner Bay | Floreana Island | Punta Cormorant | Elizabeth Bay | Urbina Bay | Vincente Roca Point | Punta Espinoza | Daphne Major | South Plaza Island | Dragon Hill | Puerto Ayora | Baltra Island

  • 02 May 2027
  • 7 Nights
Cruise From:
Was £10325pp Now: £9808pp
View cruise Enquire Enquire
REF: CELEBFL07G060-020527
Cruise From:
Was £4240pp Now: £4028pp

A Journey from Californian Treasures to Dramatic British Columbian Shores

Los Angeles | San Diego | San Francisco | Victoria | Vancouver

  • 03 May 2027
  • 7 Nights
Save up to 25% PLUS up to £2,600 Explora Credit - ENDS 28th July
Cruise From:
Was £4240pp Now: £4028pp
View cruise Enquire Enquire
REF: EXPLORAEL20270503LAXVAN
Cruise From:
Was £7849pp Now: £6985pp

27-Day World Cruise: Hawaii & Panama Canal

Honolulu | Kailua-Kona | Long Beach | Puerto Vallarta | Huatulco (Santa María Huatulco) | Puerto Chiapas | Puerto Quetzal | Puntarenas | Cartagena | Miami

  • 03 May 2027
  • 27 Nights
Cruise From:
Was £7849pp Now: £6985pp
View cruise Enquire Enquire
REF: SBN6728C

Cruise & Stay

5* Los Angeles & Miami Stays with 6* Panama Canal Crossing Cruise

Holiday prices from:
£7399pp

5* Los Angeles & Miami Stays with 6* Panama Canal Crossing Cruise

Long Beach | Puerto Vallarta | Huatulco (Santa María Huatulco) | Puerto Chiapas | Puerto Quetzal | Puntarenas | Cartagena | Miami

  • 09 May 2027
  • 23 Nights
  • Direct flights included!
  • 5* hotel stays in Los Angeles & Miami
  • 19-night ultra-luxury all-inclusive cruise
Holiday prices from:
£7399pp
View cruise
Cruise From:
Was £9407pp Now: £8936pp

7 Night Galapagos Inner Loop Cruise

Baltra Island | Rabida Island | Puerto Egas | Elizabeth Bay | Tagus Cove | Bartolome Island | Sullivan Bay | Daphne Major | North Seymour Island | Las Bachas | Punta Pitt | Puerto Baquerizo Moreno | Puerto Ayora | Baltra Island

  • 09 May 2027
  • 7 Nights
Cruise From:
Was £9407pp Now: £8936pp
View cruise Enquire Enquire
REF: CELEBFL07G059-090527
Cruise From:
Was £5949pp Now: £5294pp

19-Day World Cruise: Panama Canal Crossing

Long Beach | Puerto Vallarta | Huatulco (Santa María Huatulco) | Puerto Chiapas | Puerto Quetzal | Puntarenas | Cartagena | Miami

  • 11 May 2027
  • 19 Nights
Save up to 15% for a limited time only!
Cruise From:
Was £5949pp Now: £5294pp
View cruise Enquire Enquire
REF: SBN6731
Cruise From:
Was £9799pp Now: £8721pp

31-Day Panama Canal & Atlantic Passage

Long Beach | Puerto Vallarta | Huatulco (Santa María Huatulco) | Puerto Chiapas | Puerto Quetzal | Puntarenas | Cartagena | Miami | Funchal | Lisbon

  • 11 May 2027
  • 31 Nights
Cruise From:
Was £9799pp Now: £8721pp
View cruise Enquire Enquire
REF: SBN6731A
Cruise From:
Was £10370pp Now: £9851pp

7 Night Galapagos Outer Loop Cruise

Baltra Island | Punta Suarez | Gardner Bay | Floreana Island | Punta Cormorant | Elizabeth Bay | Urbina Bay | Vincente Roca Point | Punta Espinoza | Daphne Major | South Plaza Island | Dragon Hill | Puerto Ayora | Baltra Island

  • 16 May 2027
  • 7 Nights
Cruise From:
Was £10370pp Now: £9851pp
View cruise Enquire Enquire
REF: CELEBFL07G060-160527
Cruise From:
Was £8782pp Now: £8342pp

7 Night Galapagos Inner Loop Cruise

Baltra Island | Rabida Island | Puerto Egas | Elizabeth Bay | Tagus Cove | Bartolome Island | Sullivan Bay | Daphne Major | North Seymour Island | Las Bachas | Punta Pitt | Puerto Baquerizo Moreno | Puerto Ayora | Baltra Island

  • 23 May 2027
  • 7 Nights
Cruise From:
Was £8782pp Now: £8342pp
View cruise Enquire Enquire
REF: CELEBFL07G059-230527
Cruise From:
Was £3689pp Now: £3541pp

Panama Canal & Latin America Cruise: Mexico, Costa Rica & Colombia

San Diego | Cabo San Lucas | Acapulco | Puerto Quetzal | Acajutla | Puntarenas | Cartagena | Miami

  • 24 May 2027
  • 17 Nights
FLASH SALE! Up to 20% OFF - Ends 24th July
Up to $1,000 onboard spend
Cruise From:
Was £3689pp Now: £3541pp
View cruise Enquire Enquire
REF: AZQS270524-017
Cruise From:
Was £9419pp Now: £9042pp

San Diego to London Grand Voyage

San Diego | Cabo San Lucas | Acapulco | Puerto Quetzal | Acajutla | Puntarenas | Cartagena | Miami | New York | Newport | Boston | Halifax | Saint-John's | Cork | Plymouth | Le Havre | Tilbury

  • 24 May 2027
  • 35 Nights
FLASH SALE! Up to 20% OFF - Ends 24th July
Included in your Grand Voyage: Complimentary Airfare | Shore Excursion Credit | Upgrade Beverage package | WiFi for Two Devices | Weekly Laundry Service
Cruise From:
Was £9419pp Now: £9042pp
View cruise Enquire Enquire
REF: AZQS270524-035
Cruise From:
Was £8416pp Now: £7995pp

7 Night Galapagos Inner Loop Cruise

Baltra Island | Rabida Island | Puerto Egas | Elizabeth Bay | Tagus Cove | Bartolome Island | Sullivan Bay | Daphne Major | North Seymour Island | Las Bachas | Punta Pitt | Puerto Baquerizo Moreno | Puerto Ayora | Baltra Island

  • 06 Jun 2027
  • 7 Nights
Cruise From:
Was £8416pp Now: £7995pp
View cruise Enquire Enquire
REF: CELEBFL07G059-060627
Cruise From:
Was £10960pp Now: £10412pp

San Cristóbal to San Cristóbal

San Cristóbal Island | Roca León Dormido | Bartolome Island | Santiago Island | Punta Vicente Roca | Punta Espinoza | Elizabeth Bay | Caleta Tagus | Champion Island | Post Office Bay | Punta Cormorant | Los Gemelos | Puerto Ayora | Santa Cruz Island | Isla Guy Fawkes | Dragon Hill | San Cristóbal Island

  • 12 Jun 2027
  • 7 Nights
Save up to 40% PLUS deposits from 15%*
Cruise From:
Was £10960pp Now: £10412pp
View cruise Enquire Enquire
REF: SILVEROR270612007
Cruise From:
Was £8375pp Now: £7956pp

7 Night Galapagos Outer Loop Cruise

Baltra Island | Punta Suarez | Gardner Bay | Floreana Island | Punta Cormorant | Elizabeth Bay | Urbina Bay | Vincente Roca Point | Punta Espinoza | Daphne Major | South Plaza Island | Dragon Hill | Puerto Ayora | Baltra Island

  • 13 Jun 2027
  • 7 Nights
Cruise From:
Was £8375pp Now: £7956pp
View cruise Enquire Enquire
REF: CELEBFL07G060-130627
Cruise From:
Was £10880pp Now: £10336pp

San Cristóbal to San Cristóbal

San Cristóbal Island | Roca León Dormido | El Barranco | Darwin Bay | Sullivan Bay | North Seymour Island | Punta Moreno | Mangle Point | Los Gemelos | Puerto Ayora | Punta Suarez | Gardner Bay | Cerro Brujo | San Cristóbal Island

  • 19 Jun 2027
  • 7 Nights
Save up to 40% PLUS deposits from 15%*
Cruise From:
Was £10880pp Now: £10336pp
View cruise Enquire Enquire
REF: SILVEROR270619007
Cruise From:
Was £8231pp Now: £7819pp

7 Night Galapagos Inner Loop Cruise

Baltra Island | Rabida Island | Puerto Egas | Elizabeth Bay | Tagus Cove | Bartolome Island | Sullivan Bay | Daphne Major | North Seymour Island | Las Bachas | Punta Pitt | Puerto Baquerizo Moreno | Puerto Ayora | Baltra Island

  • 20 Jun 2027
  • 7 Nights
Cruise From:
Was £8231pp Now: £7819pp
View cruise Enquire Enquire
REF: CELEBFL07G059-200627
Cruise From:
Was £10890pp Now: £10345pp

San Cristóbal to San Cristóbal

San Cristóbal Island | Roca León Dormido | Bartolome Island | Santiago Island | Punta Vicente Roca | Punta Espinoza | Elizabeth Bay | Caleta Tagus | Champion Island | Post Office Bay | Punta Cormorant | Los Gemelos | Puerto Ayora | Santa Cruz Island | Isla Guy Fawkes | Dragon Hill | San Cristóbal Island

  • 26 Jun 2027
  • 7 Nights
Save up to 40% PLUS deposits from 15%*
Cruise From:
Was £10890pp Now: £10345pp
View cruise Enquire Enquire
REF: SILVEROR270626007
Cruise From:
Was £7700pp Now: £7315pp

7 Night Galapagos Outer Loop Cruise

Baltra Island | Punta Suarez | Gardner Bay | Floreana Island | Punta Cormorant | Elizabeth Bay | Urbina Bay | Vincente Roca Point | Punta Espinoza | Daphne Major | South Plaza Island | Dragon Hill | Puerto Ayora | Baltra Island

  • 27 Jun 2027
  • 7 Nights
Cruise From:
Was £7700pp Now: £7315pp
View cruise Enquire Enquire
REF: CELEBFL07G060-270627
Cruise From:
Was £10395pp Now: £9875pp

San Cristóbal to San Cristóbal

San Cristóbal Island | Roca León Dormido | El Barranco | Darwin Bay | Sullivan Bay | North Seymour Island | Punta Moreno | Mangle Point | Los Gemelos | Puerto Ayora | Punta Suarez | Gardner Bay | Cerro Brujo | San Cristóbal Island

  • 03 Jul 2027
  • 7 Nights
Save up to 40% PLUS deposits from 15%*
Cruise From:
Was £10395pp Now: £9875pp
View cruise Enquire Enquire
REF: SILVEROR270703007
Cruise From:
Was £8792pp Now: £8352pp

7 Night Galapagos Inner Loop Cruise

Baltra Island | Rabida Island | Puerto Egas | Elizabeth Bay | Tagus Cove | Bartolome Island | Sullivan Bay | Daphne Major | North Seymour Island | Las Bachas | Punta Pitt | Puerto Baquerizo Moreno | Puerto Ayora | Baltra Island

  • 04 Jul 2027
  • 7 Nights
Cruise From:
Was £8792pp Now: £8352pp
View cruise Enquire Enquire
REF: CELEBFL07G059-040727
Cruise From:
Was £10440pp Now: £9918pp

San Cristóbal to San Cristóbal

San Cristóbal Island | Roca León Dormido | Bartolome Island | Santiago Island | Punta Vicente Roca | Punta Espinoza | Elizabeth Bay | Caleta Tagus | Champion Island | Post Office Bay | Punta Cormorant | Los Gemelos | Puerto Ayora | Santa Cruz Island | Isla Guy Fawkes | Dragon Hill | San Cristóbal Island

  • 10 Jul 2027
  • 7 Nights
Save up to 40% PLUS deposits from 15%*
Cruise From:
Was £10440pp Now: £9918pp
View cruise Enquire Enquire
REF: SILVEROR270710007

Prices are subject to change and availability. Prices may vary depending on the airport selected. Promotions are only applicable to select cabin grades, please call for details.

Explore South America on a Finest Collection voyage

Our Finest Collection cruise packages in South America offer tailor-made adventures exclusively for you. Your cruise is paired with a set of immersive land tours dedicated to helping you get right to the heart of the ports on your itinerary. What's more, after days spent hiking across glaciers or exploring iconic cities accompanied by a local tour guide, you can retire to a five-star hotel for a gourmet dinner and spot of well-earned relaxation. 

South America expedition cruises

If you want your South America cruise adventure to be even more unforgettable, embark on an expedition cruise and feel like a true explorer. Sailing to destinations like mysterious Easter Island, wild and rugged Chile, and the positively prehistoric Galapagos islands; once-in-a-lifetime experiences are guaranteed. Accompanied by a dedicated group of expedition experts - from marine biologists to professional adventurers - you willl live like an intrepid explorer and witness natural wonders most people can only dream of.

Book South America cruises with our Cruise Concierge team

If you would like to embark on an adventure you will never forget, call our Cruise Concierge team to book one of the itineraries below. And if you can't find exactly what you are looking for? Call us to build a completely bespoke cruise in South America that incorporates every port and experience you have been dreaming of.

Our Award-Winning Service


Best Workplaces in Travel 2026
Best Workplaces in Travel 2026
UK Cruise Awards 2026 Partnership Achievement Award
UK Cruise Awards 2026 Partnership Achievement Award
Luxury Cruise Agency of the Year 2025
Luxury Cruise Agency of the Year 2025
TTG Top 20 Luxury Travel Agents 2025
TTG Top 20 Luxury Travel Agents 2025
Best Workplaces in Travel 2024
Best Workplaces in Travel 2024
TTG Luxury Cruise Agency Of The Year 2024
TTG Luxury Cruise Agency Of The Year 2024
Best Use Of Content 2023
Best Use Of Content 2023
Best Specialist Cruise Agent 2023
Best Specialist Cruise Agent 2023
UK Cruise Awards Winners 2023
UK Cruise Awards Winners 2023
Travel Weekly Large Cruise Agency of the Year 2023
Travel Weekly Large Cruise Agency of the Year 2023
Best Luxury Travel Agent 2022
Best Luxury Travel Agent 2022
Sorry, we have been unable to sign you up to receive our emails. Please use an alternative email address or try again later.
You've added to your wishlist. To view, go to Wishlist

Request a Callback