Luxury South America Cruises

Luxury cruises in South America are all about the experience. Book one of the cruise deals below and you will have the opportunity to trek through wildlife-rich jungles, marvel at thundering waterfalls, visit ancient Incan ruins, and much more. Depending on the type of cruise you book, you may also get the chance to experience something truly unique, exclusively packaged up with luxury hotel stays and one-of-a-kind tours.

Find Out More About Cruising in South America

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Finest Collection

Machu Picchu Discovery & 6* Mayan Ruin Cruise

Holiday prices from:
£9799pp

Machu Picchu Discovery & 6* Mayan Ruin Cruise

Callao | Salaverry | Guayaquil | Manta | Golfito | Panama City | Puerto Limón | Roatán Island | Harvest Caye | Costa Maya | Miami

  • 05 Mar 2027
  • 22 Nights
  • Tours in Cuzco to allow for indepth destination immersion
  • 5* hotel stays in Lima and Cuzco
  • 16-night ultra-luxury all-inclusive cruise
  • Return flights included!
Holiday prices from:
£9799pp
View cruise

TOP DEAL

Cruise From:
Was £10990pp Now: £10440pp

Puerto Williams to Puerto Williams

Puerto Williams | Antarctic Sound | Antarctic Peninsula | South Shetland Islands | Puerto Williams

  • 25 Oct 2027
  • 10 Nights
Save up to 40% PLUS deposits from 15%*
Cruise From:
Was £10990pp Now: £10440pp
View cruise Enquire Enquire
REF: SILVERWI271025010

TOP DEAL

Cruise From:
Was £13513pp Now: £12026pp

12-Day Antarctica Exploration

Buenos Aires | Ushuaia | Antarctic Experience | Ushuaia | Buenos Aires | Ushuaia

  • 17 Jan 2028
  • 13 Nights
Save up to 15% for a limited time only!
Cruise From:
Was £13513pp Now: £12026pp
View cruise Enquire Enquire
REF: SBNV811

TOP DEAL

Fly Cruise From:
Was £7079pp Now: £6739pp

Brazilian Coastal Odyssey

Bridgetown | Kingstown | Saint George's | Devil's Island | Fortaleza | Recife | Maceió | Salvador de Bahia | Rio de Janeiro

  • 08 Nov 2028
  • 14 Nights
Receive a FREE all-inclusive drinks package worth $2,238 per couple - EXCLUSIVE to SixStarCruises
Fly Cruise From:
Was £7079pp Now: £6739pp
View cruise Enquire Enquire
REF: OCEANIAARL281108
Cruise From:
Was £9357pp Now: £9076pp

Galápagos Islands – In Darwin’s Footsteps Plus Machu Picchu

Lima | Baltra Island | Mosquera Island | Punta Pitt | Puerto Baquerizo Moreno | South Plaza Island | Santa Fé Island | Puerto Ayora | Punta Suarez | Gardner Bay | North Seymour Island | El Edén Island | Baltra Island | Santa Fé Island | Santa Cruz Island | Espanola Island | North Seymour Island | Quito

  • 24 Jul 2026
  • 13 Nights
Cruise From:
Was £9357pp Now: £9076pp
View cruise Enquire Enquire
REF: HX978557978578
Cruise From:
Was £5072pp Now: £4919pp

Galápagos Islands - Nature and Wildlife Expedition Cruise | Northern Route

Baltra Island | Las Bachas | Puerto Egas | Buccaneer Cove | Bartolome Island | Rabida Island | El Barranco | Baltra Island | Darwin Bay

  • 27 Jul 2026
  • 6 Nights
Cruise From:
Was £5072pp Now: £4919pp
View cruise Enquire Enquire
REF: HX978145978162-SCGAL2627N
Cruise From:
Was £6055pp Now: £5873pp

In Darwin’s Footsteps (Eastern Route)

Lima | Baltra Island | Mosquera Island | Punta Pitt | Puerto Baquerizo Moreno | South Plaza Island | Santa Fé Island | Puerto Ayora | Punta Suarez | Gardner Bay | North Seymour Island | El Edén Island | Baltra Island | Santa Fé Island | Santa Cruz Island | Espanola Island | North Seymour Island | Quito

  • 29 Jul 2026
  • 13 Nights
Cruise From:
Was £6055pp Now: £5873pp
View cruise Enquire Enquire
REF: HURT978557978578-2
Cruise From:
Was £5560pp Now: £5393pp

Galápagos Islands – Iconic Wildlife & Sublime Scenery | Western Route

Lima | Baltra Island | Dragon Hill | Punta Vicente Roca | Puerto Ayora | Fernandina Island | Champion Island | Post Office Bay | Punta Cormorant | Baltra Island | Lima | Fernandina Beach | Santa Cruz Island | Floreana Island | Baltra Island | Santiago Island | Rabida Island | Genovesa Island | Quito

  • 04 Aug 2026
  • 15 Nights
Cruise From:
Was £5560pp Now: £5393pp
View cruise Enquire Enquire
REF: HX977785977800-SCGAL2627W
Cruise From:
Was £8100pp Now: £7857pp

Galápagos Islands - Nine of the Best Isles

Baltra Island | Dragon Hill | Punta Vicente Roca | Puerto Ayora | Fernandina Island | Champion Island | Post Office Bay | Punta Cormorant | Baltra Island | Las Bachas | Puerto Egas | Buccaneer Cove | Bartolome Island | Rabida Island | El Barranco | Baltra Island | Darwin Bay

  • 06 Aug 2026
  • 10 Nights
Cruise From:
Was £8100pp Now: £7857pp
View cruise Enquire Enquire
REF: HURT977785978180-2
Cruise From:
Was £9661pp Now: £9371pp

Galápagos Islands – In Darwin’s Footsteps Plus Machu Picchu

Lima | Baltra Island | Mosquera Island | Punta Pitt | Puerto Baquerizo Moreno | South Plaza Island | Santa Fé Island | Puerto Ayora | Punta Suarez | Gardner Bay | North Seymour Island | El Edén Island | Baltra Island | Santa Fé Island | Santa Cruz Island | Espanola Island | North Seymour Island | Quito

  • 07 Aug 2026
  • 13 Nights
Cruise From:
Was £9661pp Now: £9371pp
View cruise Enquire Enquire
REF: HX978579978600
Cruise From:
Was £6304pp Now: £5988pp

7 Night Galapagos Outer Loop Cruise

Baltra Island | Punta Suarez | Gardner Bay | Floreana Island | Punta Cormorant | Elizabeth Bay | Urbina Bay | Vincente Roca Point | Punta Espinoza | Daphne Major | South Plaza Island | Dragon Hill | Puerto Ayora | Baltra Island

  • 09 Aug 2026
  • 7 Nights
Cruise From:
Was £6304pp Now: £5988pp
View cruise Enquire Enquire
REF: CELEBFL07G058-090826
Cruise From:
Was £4626pp Now: £4487pp

Galápagos Islands - Nature and Wildlife Expedition Cruise | Northern Route

Baltra Island | Las Bachas | Puerto Egas | Buccaneer Cove | Bartolome Island | Rabida Island | El Barranco | Baltra Island | Darwin Bay

  • 10 Aug 2026
  • 6 Nights
Cruise From:
Was £4626pp Now: £4487pp
View cruise Enquire Enquire
REF: HX978163978180-SCGAL2627N
Cruise From:
Was £6359pp Now: £6168pp

In Darwin’s Footsteps (Eastern Route)

Lima | Baltra Island | Mosquera Island | Punta Pitt | Puerto Baquerizo Moreno | South Plaza Island | Santa Fé Island | Puerto Ayora | Punta Suarez | Gardner Bay | North Seymour Island | El Edén Island | Baltra Island | Santa Fé Island | Santa Cruz Island | Espanola Island | North Seymour Island | Quito

  • 12 Aug 2026
  • 13 Nights
Cruise From:
Was £6359pp Now: £6168pp
View cruise Enquire Enquire
REF: HURT978579978600-2
Cruise From:
£13778pp

Vancouver to New York City

Vancouver | Victoria | Astoria | Eureka | San Francisco | San Diego | Ensenada | Cabo San Lucas | Puerto Vallarta | Acajutla | Playa Flamingo | Puntarenas | Manta | Guayaquil | Fuerte Amador | Cartagena | Santo Domingo | Punta Cana | San Juan (Puerto Rico) | Marigot | Roseau | Bridgetown | Castries | Saint John's | Great Harbour | Samaná | Grand Turk Island | New York

  • 17 Aug 2026
  • 39 Nights
Up to 30% OFF per suite
Receive up to £3,000 Caribbean Air Credit
Cruise From:
£13778pp
View cruise Enquire Enquire
REF: CRYSTALCSY-C39-260817
Cruise From:
Was £8750pp Now: £8487pp

Galápagos Islands – In Darwin’s Footsteps Plus Machu Picchu

Lima | Baltra Island | Mosquera Island | Punta Pitt | Puerto Baquerizo Moreno | South Plaza Island | Santa Fé Island | Puerto Ayora | Punta Suarez | Gardner Bay | North Seymour Island | El Edén Island | Baltra Island | Santa Fé Island | Santa Cruz Island | Espanola Island | North Seymour Island | Quito

  • 21 Aug 2026
  • 13 Nights
Cruise From:
Was £8750pp Now: £8487pp
View cruise Enquire Enquire
REF: HX978601978622
Cruise From:
Was £3813pp Now: £3622pp

San Diego to Guayaquil

San Diego | Ensenada | Cabo San Lucas | Puerto Vallarta | Acajutla | Playa Flamingo | Puntarenas | Manta | Guayaquil

  • 24 Aug 2026
  • 12 Nights
Up to 30% OFF per suite
Receive up to £3,000 Caribbean Air Credit
Cruise From:
Was £3813pp Now: £3622pp
View cruise Enquire Enquire
REF: CRYSTALCSY-012-260824
Cruise From:
£10162pp

San Diego to New York City

San Diego | Ensenada | Cabo San Lucas | Puerto Vallarta | Acajutla | Playa Flamingo | Puntarenas | Manta | Guayaquil | Fuerte Amador | Cartagena | Santo Domingo | Punta Cana | San Juan (Puerto Rico) | Marigot | Roseau | Bridgetown | Castries | Saint John's | Great Harbour | Samaná | Grand Turk Island | New York

  • 24 Aug 2026
  • 32 Nights
Up to 30% OFF per suite
Receive up to £3,000 Caribbean Air Credit
Cruise From:
£10162pp
View cruise Enquire Enquire
REF: CRYSTALCSY-C32-260824
Cruise From:
Was £5448pp Now: £5284pp

In Darwin’s Footsteps (Eastern Route)

Lima | Baltra Island | Mosquera Island | Punta Pitt | Puerto Baquerizo Moreno | South Plaza Island | Santa Fé Island | Puerto Ayora | Punta Suarez | Gardner Bay | North Seymour Island | El Edén Island | Baltra Island | Santa Fé Island | Santa Cruz Island | Espanola Island | North Seymour Island | Quito

  • 26 Aug 2026
  • 13 Nights
Cruise From:
Was £5448pp Now: £5284pp
View cruise Enquire Enquire
REF: HURT978601978622-2
Cruise From:
Was £10970pp Now: £10640pp

Galápagos Islands - Nine of the Best Isles Plus Machu Picchu

Lima | Baltra Island | Dragon Hill | Punta Vicente Roca | Puerto Ayora | Fernandina Island | Champion Island | Post Office Bay | Punta Cormorant | Baltra Island | Las Bachas | Puerto Egas | Buccaneer Cove | Bartolome Island | Rabida Island | El Barranco | Baltra Island | Darwin Bay | Baltra Island | Santiago Island | Rabida Island | Genovesa Island | Quito

  • 27 Aug 2026
  • 15 Nights
Cruise From:
Was £10970pp Now: £10640pp
View cruise Enquire Enquire
REF: HX977817978216
Cruise From:
Was £7668pp Now: £7437pp

Galápagos Islands - Nine of the Best Isles

Lima | Baltra Island | Dragon Hill | Punta Vicente Roca | Puerto Ayora | Fernandina Island | Champion Island | Post Office Bay | Punta Cormorant | Baltra Island | Las Bachas | Puerto Egas | Buccaneer Cove | Bartolome Island | Rabida Island | El Barranco | Baltra Island | Darwin Bay | Baltra Island | Santiago Island | Rabida Island | Genovesa Island | Quito

  • 01 Sep 2026
  • 15 Nights
Cruise From:
Was £7668pp Now: £7437pp
View cruise Enquire Enquire
REF: HURT977817978216-2
Cruise From:
Was £5072pp Now: £4919pp

Galápagos Islands – Iconic Wildlife & Sublime Scenery | Western Route

Lima | Baltra Island | Dragon Hill | Punta Vicente Roca | Puerto Ayora | Fernandina Island | Champion Island | Post Office Bay | Punta Cormorant | Baltra Island | Lima | Fernandina Beach | Santa Cruz Island | Floreana Island | Baltra Island | Santiago Island | Rabida Island | Genovesa Island | Quito

  • 01 Sep 2026
  • 15 Nights
Cruise From:
Was £5072pp Now: £4919pp
View cruise Enquire Enquire
REF: HX977817977832-SCGAL2627W
Cruise From:
Was £9054pp Now: £8782pp

Galápagos Islands – In Darwin’s Footsteps Plus Machu Picchu

Lima | Baltra Island | Mosquera Island | Punta Pitt | Puerto Baquerizo Moreno | South Plaza Island | Santa Fé Island | Puerto Ayora | Punta Suarez | Gardner Bay | North Seymour Island | El Edén Island | Baltra Island | Santa Fé Island | Santa Cruz Island | Espanola Island | North Seymour Island | Quito

  • 04 Sep 2026
  • 13 Nights
Cruise From:
Was £9054pp Now: £8782pp
View cruise Enquire Enquire
REF: HX978623978644
Cruise From:
Was £3148pp Now: £2990pp

Guayaquil to San Juan

Guayaquil | Fuerte Amador | Cartagena | Santo Domingo | Punta Cana | San Juan (Puerto Rico)

  • 05 Sep 2026
  • 9 Nights
Up to 30% OFF per suite
Receive up to £3,000 Caribbean Air Credit
Cruise From:
Was £3148pp Now: £2990pp
View cruise Enquire Enquire
REF: CRYSTALCSY-009-260905
Cruise From:
Was £5072pp Now: £4919pp

Galápagos Islands - Nature and Wildlife Expedition Cruise | Northern Route

Baltra Island | Las Bachas | Puerto Egas | Buccaneer Cove | Bartolome Island | Rabida Island | El Barranco | Baltra Island | Darwin Bay

  • 07 Sep 2026
  • 6 Nights
Cruise From:
Was £5072pp Now: £4919pp
View cruise Enquire Enquire
REF: HX978199978216-SCGAL2627N
Cruise From:
Was £5752pp Now: £5579pp

In Darwin’s Footsteps (Eastern Route)

Lima | Baltra Island | Mosquera Island | Punta Pitt | Puerto Baquerizo Moreno | South Plaza Island | Santa Fé Island | Puerto Ayora | Punta Suarez | Gardner Bay | North Seymour Island | El Edén Island | Baltra Island | Santa Fé Island | Santa Cruz Island | Espanola Island | North Seymour Island | Quito

  • 09 Sep 2026
  • 13 Nights
Cruise From:
Was £5752pp Now: £5579pp
View cruise Enquire Enquire
REF: HURT978623978644-2
Cruise From:
Was £10585pp Now: £10267pp

Galápagos Islands - Nine of the Best Isles Plus Machu Picchu

Lima | Baltra Island | Dragon Hill | Punta Vicente Roca | Puerto Ayora | Fernandina Island | Champion Island | Post Office Bay | Punta Cormorant | Baltra Island | Las Bachas | Puerto Egas | Buccaneer Cove | Bartolome Island | Rabida Island | El Barranco | Baltra Island | Darwin Bay | Baltra Island | Santiago Island | Rabida Island | Genovesa Island | Quito

  • 10 Sep 2026
  • 15 Nights
Cruise From:
Was £10585pp Now: £10267pp
View cruise Enquire Enquire
REF: HX977833978234
Cruise From:
Was £7283pp Now: £7064pp

Galápagos Islands - Nine of the Best Isles

Lima | Baltra Island | Santiago Island | Rabida Island | Genovesa Island | Quito

  • 15 Sep 2026
  • 15 Nights
Cruise From:
Was £7283pp Now: £7064pp
View cruise Enquire Enquire
REF: HURT977833978234-2
Cruise From:
Was £9054pp Now: £8782pp

Galápagos Islands – In Darwin’s Footsteps Plus Machu Picchu

Lima | Baltra Island | Mosquera Island | Punta Pitt | Puerto Baquerizo Moreno | South Plaza Island | Santa Fé Island | Puerto Ayora | Punta Suarez | Gardner Bay | North Seymour Island | El Edén Island | Baltra Island | Santa Fé Island | Santa Cruz Island | Espanola Island | North Seymour Island | Quito

  • 18 Sep 2026
  • 13 Nights
Cruise From:
Was £9054pp Now: £8782pp
View cruise Enquire Enquire
REF: HX978645978666
Cruise From:
Was £8960pp Now: £8512pp

San Cristóbal to San Cristóbal

San Cristóbal Island | Roca León Dormido | Bartolome Island | Santiago Island | Punta Vicente Roca | Punta Espinoza | Elizabeth Bay | Caleta Tagus | Champion Island | Post Office Bay | Punta Cormorant | Los Gemelos | Puerto Ayora | Isla Guy Fawkes | Dragon Hill | San Cristóbal Island

  • 19 Sep 2026
  • 7 Nights
Save up to 40% PLUS deposits from 15%*
Amazing Last Minute fares!*
Cruise From:
Was £8960pp Now: £8512pp
View cruise Enquire Enquire
REF: SILVEROR260919007
Cruise From:
Was £11725pp Now: £11138pp

7 Night Galapagos Outer Loop Cruise

Baltra Island | Punta Suarez | Gardner Bay | Floreana Island | Punta Cormorant | Elizabeth Bay | Urbina Bay | Vincente Roca Point | Punta Espinoza | Daphne Major | South Plaza Island | Dragon Hill | Puerto Ayora | Baltra Island

  • 20 Sep 2026
  • 7 Nights
Cruise From:
Was £11725pp Now: £11138pp
View cruise Enquire Enquire
REF: CELEBFL07G058-200926

Prices are subject to change and availability. Prices may vary depending on the airport selected. Promotions are only applicable to select cabin grades, please call for details.

Explore South America on a Finest Collection voyage

Our Finest Collection cruise packages in South America offer tailor-made adventures exclusively for you. Your cruise is paired with a set of immersive land tours dedicated to helping you get right to the heart of the ports on your itinerary. What's more, after days spent hiking across glaciers or exploring iconic cities accompanied by a local tour guide, you can retire to a five-star hotel for a gourmet dinner and spot of well-earned relaxation. 

South America expedition cruises

If you want your South America cruise adventure to be even more unforgettable, embark on an expedition cruise and feel like a true explorer. Sailing to destinations like mysterious Easter Island, wild and rugged Chile, and the positively prehistoric Galapagos islands; once-in-a-lifetime experiences are guaranteed. Accompanied by a dedicated group of expedition experts - from marine biologists to professional adventurers - you willl live like an intrepid explorer and witness natural wonders most people can only dream of.

Book South America cruises with our Cruise Concierge team

If you would like to embark on an adventure you will never forget, call our Cruise Concierge team to book one of the itineraries below. And if you can't find exactly what you are looking for? Call us to build a completely bespoke cruise in South America that incorporates every port and experience you have been dreaming of.

Our Award-Winning Service


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