Luxury South America Cruises

Luxury cruises in South America are all about the experience. Book one of the cruise deals below and you will have the opportunity to trek through wildlife-rich jungles, marvel at thundering waterfalls, visit ancient Incan ruins, and much more. Depending on the type of cruise you book, you may also get the chance to experience something truly unique, exclusively packaged up with luxury hotel stays and one-of-a-kind tours.

Find Out More About Cruising in South America


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Iguazu Falls & Beautiful Brazil Cruise
Buenos Aires | Buenos Aires | Montevideo | Punta del Este | Balneário de Camboriú | São Francisco do Sul | Santos | Parati | Ilha Grande | Buzios | Rio de Janeiro | Rio de Janeiro
19 Mar 2025
18 Nights
South America

FREE simply MORE shore excursion credit, FREE gratuities, FREE Champagne, wine and more, FREE speciality dining and FREE Wi-Fi available on EVERY booking
Ends 30th September - Last chance to book and receive a FREE house select beverage package
SixStarCruises FLASH SALE - Save up to an EXTRA £300* off advertised prices
HOLIDAY PRICES FROM

Now: £5299
pp
REF: OCEANIAMNA250324-2

Finest Collection

7 Night Galapagos Inner Loop Cruise
Baltra Island, Galápagos | Rabida Island | Puerto Egas | Bahía Borrero, Santa Cruz Island, Galápagos | Dragon Hill, Santa Cruz Island, Galápagos | Bartolome Island | Sullivan Bay, Santiago Island, Galápagos | Daphne Major, Galapagos | North Seymour Island, Galapagos | Las Bachas, Santa Cruz Island, Galápagos | San Cristóbal Island, Galápagos | Puerto Baquerizo Moreno, San Cristobal Island, Galapagos | Puerto Ayora, Isla Santa Cruz | Baltra Island, Galápagos More...
29 Sep 2024
7 Nights
Pacific

SixStarCruises FLASH SALE - Save up to an EXTRA £300* off advertised prices
Cruise Only From
Was £7755pp
Now: £5903
pp
REF: CELEBFL07G045-290924
7 Night Galapagos Outer Loop Cruise
Baltra Island, Galápagos | Punta Suarez, Isla Española, Galápagos | Gardner Bay, Española Island, Galápagos | Floreana Island, Galapagos | Punta Cormorant, Floreana Island, Galápagos | South Plaza Island, Galápagos | Santa Fé Island, Galápagos | Bartolome Island | Sullivan Bay, Santiago Island, Galápagos | Daphne Major, Galapagos | Bahía Borrero, Santa Cruz Island, Galápagos | Dragon Hill, Santa Cruz Island, Galápagos | Puerto Ayora, Isla Santa Cruz | Baltra Island, Galápagos More...
06 Oct 2024
7 Nights
Pacific

SixStarCruises FLASH SALE - Save up to an EXTRA £300* off advertised prices
Cruise Only From
Was £14921pp
Now: £13608
pp
REF: CELEBFL07G046-061024
14-Day Wild Guianas To The Amazon Basin
Bridgetown | Port-of-Spain | Port-of-Spain | Devil's Island | Macapa | Santarém | Amazon Experience | Amazon Experience | Parintins | Amazon Experience | Amazon Experience | Manaus
07 Oct 2024
14 Nights
South America

Sail into Savings - Save up to 15% on selected Ocean and Expedition Voyages
SixStarCruises FLASH SALE - Save up to an EXTRA £300* off advertised prices
Cruise Only From
Was £7904pp
Now: £6983
pp
REF: SBNV458
San Cristóbal to San Cristóbal
San Cristóbal Island, Galápagos | Roca León Dormido | El Barranco, Genovesa Island, Galápagos | Darwin Bay, Genovesa Island, Galápagos | Sullivan Bay, Santiago Island, Galápagos | North Seymour Island, Galapagos | Punta Moreno, Isabella Island, Galapagos | Mangle Point, Fernandina Island, Galápagos | Los Gemelos, Santa Cruz Island, Galápagos | Puerto Ayora, Isla Santa Cruz | Punta Suarez, Isla Española, Galápagos | Gardner Bay, Española Island, Galápagos | Cerro Brujo, San Cristóbal Island, Galápagos | San Cristóbal Island, Galápagos | More...
12 Oct 2024
7 Nights
Pacific

Save £2400 per couple
SixStarCruises FLASH SALE - Save up to an EXTRA £300* off advertised prices
Fly Cruise From
Was £16200pp
Now: £15390
pp
REF: SILVEROR241012007
7 Night Galapagos Inner Loop Cruise
Baltra Island, Galápagos | Rabida Island | Puerto Egas | Bahía Borrero, Santa Cruz Island, Galápagos | Dragon Hill, Santa Cruz Island, Galápagos | Bartolome Island | Sullivan Bay, Santiago Island, Galápagos | Daphne Major, Galapagos | North Seymour Island, Galapagos | Las Bachas, Santa Cruz Island, Galápagos | San Cristóbal Island, Galápagos | Puerto Baquerizo Moreno, San Cristobal Island, Galapagos | Puerto Ayora, Isla Santa Cruz | Baltra Island, Galápagos More...
13 Oct 2024
7 Nights
Pacific

SixStarCruises FLASH SALE - Save up to an EXTRA £300* off advertised prices
Cruise Only From
Was £8003pp
Now: £7299
pp
REF: CELEBFL07G045-131024
13-Night Las Palmas to Rio de Janeiro
Las Palmas de Gran Canaria | Mindelo, São Vicente Island | Praia, Santiago Island | Rio de Janeiro
14 Oct 2024
13 Nights
South America

ALWAYS INCLUDED: cultural immersion, gourmet dining, unlimited beverages, including fine wines, spirits and craft beers, stocked in-room minibar, 24-hour room service, pre-paid gratuities PLUS MUCH MORE!
Cultural Expedition
SixStarCruises FLASH SALE - Save up to an EXTRA £300* off advertised prices
Fly Cruise From
Was £3829pp
Now: £3739
pp
REF: ATLASVOYWNA241014
Papeete to Valparaiso
Papeete, Tahiti | Fakarava | Atuona, Hiva Oa | Tahuata Island | Hatiheu | Hana Vave, Fatu Hiva Island | Mangareva Island | Pitcairn Island | Pitcairn Island | Hangaroa, Easter Island | Hangaroa, Easter Island | Alejandro Selkirk Island | San Juan Bautista (Robinson Crusoe Island) | Valparaiso More...
15 Oct 2024
23 Nights
Pacific

$250 FREE to spend on-board - ONLY when booking with SixStarCruises
Save £2400 per couple
SixStarCruises FLASH SALE - Save up to an EXTRA £300* off advertised prices
Fly Cruise From
Was £23000pp
Now: £20757
pp
REF: SILVERE4241015023
18-Day Chilean Fjords & Antarctica
San Antonio | Puerto Montt | Caleta Tortel | PIO X Glacier | El Brujo Glacier | Punta Arenas | Punta Arenas | Antarctic Experience | Antarctic Experience | Antarctic Experience | Antarctic Experience | Antarctic Experience | Buenos Aires | Ushuaia More...
17 Oct 2024
18 Nights
Antarctica

Sail into Savings - Save up to 15% on selected Ocean and Expedition Voyages
SixStarCruises FLASH SALE - Save up to an EXTRA £300* off advertised prices
Cruise Only From
Was £8753pp
Now: £7734
pp
REF: SBNP458
San Cristóbal to San Cristóbal
San Cristóbal Island, Galápagos | Roca León Dormido | Bartolome Island | Santiago Island, Galápagos | Punta Vicente Roca, Isabela Island, Galápagos | Punta Espinoza, Fernandina Island, Galápagos | Elizabeth Bay, Isabela Island, Galápagos | Caleta Tagus | Champion Island, Galápagos | Post Office Bay, Floreana, Galápagos | Punta Cormorant, Floreana Island, Galápagos | Los Gemelos, Santa Cruz Island, Galápagos | Puerto Ayora, Isla Santa Cruz | Santa Cruz Island, Galápagos | More...
19 Oct 2024
7 Nights
Pacific

Save £2400 per couple
SixStarCruises FLASH SALE - Save up to an EXTRA £300* off advertised prices
Fly Cruise From
Was £29000pp
Now: £12635
pp
REF: SILVEROR241019007
14-Day Amazon Delta & Coast Of Brazil
Manaus | Manaus | Amazon Experience | Parintins | Santarém | Amazon Experience | Macapa | Natal | Rio de Janeiro
21 Oct 2024
14 Nights
South America

Sail into Savings - Save up to 15% on selected Ocean and Expedition Voyages
SixStarCruises FLASH SALE - Save up to an EXTRA £300* off advertised prices
Cruise Only From
Was £5949pp
Now: £5256
pp
REF: SBNV459
San Cristóbal to San Cristóbal
San Cristóbal Island, Galápagos | Roca León Dormido | El Barranco, Genovesa Island, Galápagos | Darwin Bay, Genovesa Island, Galápagos | Sullivan Bay, Santiago Island, Galápagos | North Seymour Island, Galapagos | Punta Moreno, Isabella Island, Galapagos | Mangle Point, Fernandina Island, Galápagos | Los Gemelos, Santa Cruz Island, Galápagos | Puerto Ayora, Isla Santa Cruz | Punta Suarez, Isla Española, Galápagos | Gardner Bay, Española Island, Galápagos | Cerro Brujo, San Cristóbal Island, Galápagos | San Cristóbal Island, Galápagos | More...
26 Oct 2024
7 Nights
Pacific

Save £2400 per couple
SixStarCruises FLASH SALE - Save up to an EXTRA £300* off advertised prices
Fly Cruise From
Was £28500pp
Now: £12920
pp
REF: SILVEROR241026007
San Cristóbal, Galapagos to San Cristóbal, Galapagos
San Cristóbal Island, Galápagos | Roca León Dormido | El Barranco, Genovesa Island, Galápagos | Darwin Bay, Genovesa Island, Galápagos | Sullivan Bay, Santiago Island, Galápagos | North Seymour Island, Galapagos | Punta Moreno, Isabella Island, Galapagos | Mangle Point, Fernandina Island, Galápagos | Los Gemelos, Santa Cruz Island, Galápagos | Puerto Ayora, Isla Santa Cruz | Punta Suarez, Isla Española, Galápagos | Gardner Bay, Española Island, Galápagos | Cerro Brujo, San Cristóbal Island, Galápagos | San Cristóbal Island, Galápagos | More...
26 Oct 2024
14 Nights
South America

Save £2400 per couple
SixStarCruises FLASH SALE - Save up to an EXTRA £300* off advertised prices
Fly Cruise From
Was £49300pp
Now: £21660
pp
REF: SILVEROR241026C14
7 Night Galapagos Inner Loop Cruise
Baltra Island, Galápagos | Rabida Island | Puerto Egas | Bahía Borrero, Santa Cruz Island, Galápagos | Dragon Hill, Santa Cruz Island, Galápagos | Bartolome Island | Sullivan Bay, Santiago Island, Galápagos | Daphne Major, Galapagos | North Seymour Island, Galapagos | Las Bachas, Santa Cruz Island, Galápagos | San Cristóbal Island, Galápagos | Puerto Baquerizo Moreno, San Cristobal Island, Galapagos | Puerto Ayora, Isla Santa Cruz | Baltra Island, Galápagos More...
27 Oct 2024
7 Nights
Pacific

SixStarCruises FLASH SALE - Save up to an EXTRA £300* off advertised prices
Cruise Only From
Was £14353pp
Now: £9770
pp
REF: CELEBFL07G045-271024
Puerto Williams to Puerto Williams
Puerto Williams | New Island | West Point Island | Port Stanley | South Georgia Island | South Georgia Island | South Georgia Island | Elephant Island, South Shetland Islands | Antarctic Sound | Antarctic Peninsula | Antarctic Peninsula | South Shetland Islands | Puerto Williams | Puerto Williams More...
29 Oct 2024
18 Nights
Antarctica

Save £2400 per couple
SixStarCruises FLASH SALE - Save up to an EXTRA £300* off advertised prices
Fly Cruise From
Was £23700pp
Now: £21389
pp
REF: SILVEREV241029018
Puntarenas to Valparaiso
Puntarenas | Playa Panama | Punta Leona | Golfito | Cocos Island | Cocos Island | Puerto Lopez | Callao | Paracas | Arica | Antofagasta | Isla Pan de Azúcar | Coquimbo | Valparaiso More...
31 Oct 2024
18 Nights
South America

Save £2400 per couple
SixStarCruises FLASH SALE - Save up to an EXTRA £300* off advertised prices
Fly Cruise From
Was £13300pp
Now: £12003
pp
REF: SILVERWI241031018
San Cristóbal to San Cristóbal
San Cristóbal Island, Galápagos | Roca León Dormido | Bartolome Island | Santiago Island, Galápagos | Punta Vicente Roca, Isabela Island, Galápagos | Punta Espinoza, Fernandina Island, Galápagos | Elizabeth Bay, Isabela Island, Galápagos | Caleta Tagus | Champion Island, Galápagos | Post Office Bay, Floreana, Galápagos | Punta Cormorant, Floreana Island, Galápagos | Los Gemelos, Santa Cruz Island, Galápagos | Puerto Ayora, Isla Santa Cruz | Santa Cruz Island, Galápagos | More...
02 Nov 2024
7 Nights
Pacific

Save £2400 per couple
SixStarCruises FLASH SALE - Save up to an EXTRA £300* off advertised prices
Fly Cruise From
Was £28300pp
Now: £13015
pp
REF: SILVEROR241102007
Wellness Retreat: Barbados to Brazil
Bridgetown | Devil's Island | Recife | Rio de Janeiro
05 Nov 2024
11 Nights
South America

Celebrate 5 years of Scenic Ocean with an ADDITIONAL 5% off ALL sailings - Call for your extra savings
Save up to 30%, return flights included and free private door to door transfers*
SixStarCruises FLASH SALE - Save up to an EXTRA £300* off advertised prices
Fly Cruise From
Was £9630pp
Now: £5219
pp
REF: SCENIC501R051124-1
Antarctic Peninsula In Depth
Ushuaia | Ushuaia | Antarctic Peninsula | Antarctic Peninsula | Antarctic Peninsula | Antarctic Peninsula | Antarctic Peninsula | Antarctic Peninsula | Antarctic Peninsula | Antarctic Peninsula | Ushuaia
06 Nov 2024
14 Nights
Antarctica

SixStarCruises FLASH SALE - Save up to an EXTRA £300* off advertised prices
Cruise Only From
Was £10403pp
Now: £10090
pp
REF: AURORAAPD003G
Valparaiso to Puerto Williams
Valparaiso | Niebla | Castro | Caleta Tortel | Chilean Fjords | Chilean Fjords | Chilean Fjords | Punta Arenas | Ushuaia | Puerto Williams
07 Nov 2024
12 Nights
South America

Save £2400 per couple
SixStarCruises FLASH SALE - Save up to an EXTRA £300* off advertised prices
Fly Cruise From
Was £8500pp
Now: £7671
pp
REF: SILVERE4241107012
Amazonian Mystique
Miami, Florida | Saint John's | Castries | Saint George's | Port-of-Spain | Macapa | Santarém | Boca de Valeria | Manaus | Parintins | Alter do Chão | Macapa | Bridgetown | Roseau | More...
09 Nov 2024
24 Nights
South America

FREE simply MORE shore excursion credit, FREE gratuities, FREE Champagne, wine and more, FREE speciality dining and FREE Wi-Fi available on EVERY booking
SixStarCruises FLASH SALE - Save up to an EXTRA £300* off advertised prices
Fly Cruise From
Was £6249pp
Now: £5936
pp
REF: OCEANIANAU241109
18-Day Panama Canal Passage
Miami, Florida | Cartagena | Puntarenas | Puerto Quetzal | Puerto Chiapas | Huatulco (Santa María Huatulco) | Cabo San Lucas | Los Angeles, California
09 Nov 2024
18 Nights
Panama Canal

Sail into Savings - Save up to 15% on selected Ocean and Expedition Voyages
Save up to 30%*
SixStarCruises FLASH SALE - Save up to an EXTRA £300* off advertised prices
Fly Cruise From
Was £9085pp
Now: £5499
pp
REF: SBN6467
7 Night Galapagos Inner Loop Cruise
Baltra Island, Galápagos | Rabida Island | Puerto Egas | Bahía Borrero, Santa Cruz Island, Galápagos | Dragon Hill, Santa Cruz Island, Galápagos | Bartolome Island | Sullivan Bay, Santiago Island, Galápagos | Daphne Major, Galapagos | North Seymour Island, Galapagos | Las Bachas, Santa Cruz Island, Galápagos | San Cristóbal Island, Galápagos | Puerto Baquerizo Moreno, San Cristobal Island, Galapagos | Puerto Ayora, Isla Santa Cruz | Baltra Island, Galápagos More...
10 Nov 2024
7 Nights
Pacific

SixStarCruises FLASH SALE - Save up to an EXTRA £300* off advertised prices
Cruise Only From
Was £17579pp
Now: £10983
pp
REF: CELEBFL07G045-101124

Explore South America on a Finest Collection voyage

Our Finest Collection cruise packages in South America offer tailor-made adventures exclusively for you. Your cruise is paired with a set of immersive land tours dedicated to helping you get right to the heart of the ports on your itinerary. What's more, after days spent hiking across glaciers or exploring iconic cities accompanied by a local tour guide, you can retire to a five-star hotel for a gourmet dinner and spot of well-earned relaxation. 

South America expedition cruises

If you want your South America cruise adventure to be even more unforgettable, embark on an expedition cruise and feel like a true explorer. Sailing to destinations like mysterious Easter Island, wild and rugged Chile, and the positively prehistoric Galapagos islands; once-in-a-lifetime experiences are guaranteed. Accompanied by a dedicated group of expedition experts - from marine biologists to professional adventurers - you willl live like an intrepid explorer and witness natural wonders most people can only dream of.

Book South America cruises with our Cruise Concierge team

If you would like to embark on an adventure you will never forget, call our Cruise Concierge team to book one of the itineraries below. And if you can't find exactly what you are looking for? Call us to build a completely bespoke cruise in South America that incorporates every port and experience you have been dreaming of.

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