South America Cruise Deals

South America is a land of exotic wildlife and unique cultures; offering authentic experiences to all who travel there. Luxury South America cruises are the perfect way to experience this region in all its glory, visiting spectacular ports like Buenos Aires, Cusco and the Galapagos islands - you could even cruise to Ushuaia, the gateway to Antarctica.

Experience the unforgettable on South America cruises

Luxury cruises in South America are all about the experience. Book one of the cruise deals below and you will have the opportunity to trek through wildlife-rich jungles, marvel at thundering waterfalls, visit ancient Incan ruins, and much more. Depending on the type of cruise you book, you may also get the chance to experience something truly unique, exclusively packaged up with luxury hotel stays and one-of-a-kind tours.

Explore South America on a Finest Collection voyage

Our Finest Collection cruise packages in South America offer tailor-made adventures exclusively for you. Your cruise is paired with a set of immersive land tours dedicated to helping you get right to the heart of the ports on your itinerary. What's more, after days spent hiking across glaciers or exploring iconic cities accompanied by a local tour guide, you can retire to a five-star hotel for a gourmet dinner and spot of well-earned relaxation.

South America expedition cruises

If you want your South America cruise adventure to be even more unforgettable, embark on an expedition cruise and feel like a true explorer. Sailing to destinations like mysterious Easter Island, wild and rugged Chile, and the positively prehistoric Galapagos islands; once-in-a-lifetime experiences are guaranteed. Accompanied by a dedicated group of expedition experts - from marine biologists to professional adventurers - you willl live like an intrepid explorer and witness natural wonders most people can only dream of.

Book South America cruises with our Cruise Concierge team

If you would like to embark on an adventure you will never forget, call our Cruise Concierge team to book one of the itineraries below. And if you can't find exactly what you are looking for? Call us to build a completely bespoke cruise in South America that incorporates every port and experience you have been dreaming of.

2 The Americas & Chilean Fjords
10 October 2019 - 86 nights

New York, United States | New York, United States | Hamilton | Hamilton | St. John's, Antigua | Roseau | Basseterre | Basseterre | Philipsburg, St Maarten | Tortola | St. Thomas | San Juan | San Juan | San Juan | Bridgetown | French Guiana, France | Santarem | Parintins | Manaus, Brazil | Manaus, Brazil | Manaus, Brazil | Recife | Salvador Da Bahia | Rio De Janeiro | Rio De Janeiro | Rio De Janeiro | Montevideo | Buenos Aires | Buenos Aires | Montevideo | Puerto Madryn | Falkland Islands, United Kingdom | Falkland Islands, United Kingdom | Ushuaia, Argentina | Punta Arenas, Chile | Puerto Chacabuco | Puerto Montt, Chile | Valparaiso, Chile | Valparaiso, Chile | Valparaiso, Chile | Valparaiso, Chile | La Serena | Iquique | Arequipa | Pisco (San Martin) | Lima, Peru | Quito (Manta) | Panama City (Fuerte Amador), Panama | Puntarenas, Costa Rica | Puerto Quetzal, Guatemala | Cabo San Lucas, Mexico | San Diego | Los Angeles, California | Los Angeles, California | Los Angeles, California more

Fly Cruise£33695pp
Cruise OnlyCall
3 Fort Lauderdale, Florida to Callao ( Lima)
11 October 2019 - 19 nights

Ft. Lauderdale | Harbour Island | Conception Island | Providencia Island | San Andres Island, Colombia | Bocas Del Toro, Panama | Colon, Panama | Quepos, Costa Rica | Golfito, Costa Rica | Isla De La Plata, Ecuador | Machala, Ecuador | Salaverry, Peru | Callao (Lima) more

Fly Cruise£10099pp
Cruise Only£11539pp
4 Caribbean & South American Shores
24 October 2019 - 25 nights

San Juan | San Juan | Bridgetown | French Guiana, France | Santarem | Parintins | Manaus, Brazil | Manaus, Brazil | Recife | Salvador Da Bahia | Rio De Janeiro | Rio De Janeiro | Montevideo | Buenos Aires more

Fly Cruise£5290pp
Cruise OnlyCall
5 West Indies, Amazon & South America
24 October 2019 - 46 nights

San Juan | San Juan | Bridgetown | French Guiana, France | Santarem | Parintins | Manaus, Brazil | Manaus, Brazil | Recife | Salvador Da Bahia | Rio De Janeiro | Rio De Janeiro | Montevideo | Buenos Aires | Buenos Aires | Montevideo | Puerto Madryn | Falkland Islands, United Kingdom | Falkland Islands, United Kingdom | Ushuaia, Argentina | Punta Arenas, Chile | Puerto Chacabuco | Puerto Montt, Chile | Valparaiso, Chile | Valparaiso, Chile more

Fly Cruise£11990pp
Cruise Only£18290pp
6 Call(Lima) to Buenos Aires
30 October 2019 - 25 nights

Lima, Peru | Paracas, Peru | Arica | Antofagasta, Chile | Isla Pan De Acuzar | Coquimbo | Valparaiso, Chile | Niebla | Puerto Montt, Chile | Castro, Chile | Tortel, Chile | Punta Arenas, Chile | Puerto Deseado | Camarones, Argentina | Puerto Madryn | Buenos Aires more

Fly Cruise£13579pp
Cruise Only£13579pp
7 Galapagos Inner Loop
03 November 2019 - 7 nights

Baltra, Galapagos, Ecuador | Daphne Island (Galapagos) | Egas Port | Rabida, Ecuador | Bahia Elizabeth, Isabela, Ecuador | Tagus Cove (Isabella) | Bahia Sullivan, Santiago, Ecuador | Bartolome Island | Las Blachas, Santa Cruz, Ecuador | Seymour Norte, Ecuador | Puerto Baquerizo (Cristobal) | Punta Pitt (San Cristobal) | Estacion Darwin & Puerto Ayora,Santa Cruz, Ecuado | Baltra, Galapagos, Ecuador more

Fly CruiseCall
Cruise Only£6869pp
8 Panama Canal & Inca Gold
06 November 2019 - 13 nights

Miami, Florida | Fuerte Amador | Manta, Ecuador | Manta, Ecuador | Machala, Ecuador | Salaverry, Peru | Callao (Lima) | Callao (Lima) more

Fly Cruise£5499pp
Cruise Only£4649pp
9 Guayaquil to Valparaiso
09 November 2019 - 14 nights

Guayaquil | Lobos De Tierra Island, Peru | Salaverry, Peru | Islas Guanape, Peru | Callao (Lima) | Paracas, Peru | Arequipa Matarani | Arica | Antofagasta, Chile | Isla Pan De Acuzar | Isla Chanaral, Chile | Coquimbo | Valparaiso, Chile more

Fly Cruise£9929pp
Cruise Only£9929pp
10 Southern Atlantic Crossing from Barcelona
13 November 2019 - 21 nights

Barcelona | Barcelona | Granada (Malaga) | Casablanca | Dakar, Senegal | Recife | Rio De Janeiro | Montevideo | Buenos Aires | Buenos Aires more

Fly Cruise£4390pp
Cruise OnlyCall
11 Portuguese Discoveries
13 November 2019 - 17 nights

Lisbon | Funchal | Santa Cruz De La Palma | Tenerife | Mindelo, Cape Verde | Salvador Da Bahia | Vitória | Rio De Janeiro | Rio De Janeiro more

Fly Cruise£2979pp
Cruise Only£2489pp
12 Lima to Buenos Aries
16 November 2019 - 21 nights

Lima, Peru | Pisco (San Martin) | Arequipa Matarani | Antofagasta, Chile | Coquimbo | Santiago | Puerto Montt, Chile | Puerto Chacabuco | Punta Arenas, Chile | Ushuaia, Argentina | Port Stanley | Punta Del Este | Montevideo | Buenos Aires | Buenos Aires more

Fly Cruise£9699pp
Cruise Only£8829pp
13 Galapagos Inner Loop
17 November 2019 - 7 nights

Baltra, Galapagos, Ecuador | Daphne Island (Galapagos) | Egas Port | Rabida, Ecuador | Bahia Elizabeth, Isabela, Ecuador | Tagus Cove (Isabella) | Bahia Sullivan, Santiago, Ecuador | Bartolome Island | Las Blachas, Santa Cruz, Ecuador | Seymour Norte, Ecuador | Puerto Baquerizo (Cristobal) | Punta Pitt (San Cristobal) | Estacion Darwin & Puerto Ayora,Santa Cruz, Ecuado | Baltra, Galapagos, Ecuador more

Fly Cruise£7879pp
Cruise Only£6899pp
14 Exploring the Americas
18 November 2019 - 47 nights

Buenos Aires | Buenos Aires | Montevideo | Puerto Madryn | Falkland Islands, United Kingdom | Falkland Islands, United Kingdom | Ushuaia, Argentina | Punta Arenas, Chile | Puerto Chacabuco | Puerto Montt, Chile | Valparaiso, Chile | Valparaiso, Chile | Valparaiso, Chile | La Serena | Iquique | Arequipa | Pisco (San Martin) | Lima, Peru | Quito (Manta) | Panama City (Fuerte Amador), Panama | Puntarenas, Costa Rica | Puerto Quetzal, Guatemala | Cabo San Lucas, Mexico | San Diego | Los Angeles, California | Los Angeles, California more

Fly Cruise£11990pp
Cruise OnlyCall
15 Treasures Of The Inca Coast
19 November 2019 - 9 nights

Callao (Lima) | Islas Ballestas | Pisco (San Martin) | Punta Islay, Peru | Arequipa Matarani | Arica | Iquique | Antofagasta, Chile | Isla Pan De Azucar | Santiago (San Antonio) more

Fly Cruise£3249pp
Cruise Only£2799pp
16 Los Angeles To Chile
20 November 2019 - 16 nights

Los Angeles, California | Cabo San Lucas, Mexico | Puerto Vallarta, Mexico | Huatulco | Caldera, Costa Rica | Manta, Ecuador | Callao (Lima) | Arica | Santiago (San Antonio) more

Fly Cruise£4649pp
Cruise Only£3329pp
17 Amazon Interlude - Miami to Miami
23 November 2019 - 25 nights

Miami, Florida | Gustavia | Castries | Port Of Spain | Santarem | Boca Da Valeria | Manaus | Manaus | Parintins | Alter Do Chao | Devil's Island | Bridgetown | St John S, Antigua | San Juan | Punta Cana, Domnican Republic | Miami, Florida more

Fly Cruise£5199pp
Cruise Only£4429pp
18 Catalonia & Canaries - Barcelona to Rio De Janerio
23 November 2019 - 14 nights

Barcelona | Santa Cruz De Tenerife | San Sebastian, La Gomera | Mindelo (Sao Vicente) | Recife | Rio De Janeiro | Rio De Janeiro more

Fly Cruise£2449pp
Cruise Only£1789pp
19 Valparaiso to Ushuaia
23 November 2019 - 12 nights

Valparaiso, Chile | Niebla | Puerto Montt, Chile | Castro, Chile | Puerto Natales, Chile | Puerto Natales, Chile | Puerto Natales, Chile | Punta Arenas, Chile | Ushuaia, Argentina more

Fly CruiseCall
Cruise OnlyCall
20 South America -Buenos Aires To Ushuaia
24 November 2019 - 16 nights

Buenos Aires | Puerto Madryn | New Island | West Point Island, Falkland Islands | Port Stanley | Elephant Island | Antarctic Peninsula, Antarctica | Antarctic Peninsula, Antarctica | Antarctic Peninsula, Antarctica | South Shetland Islands | Ushuaia, Argentina more

Fly Cruise£15899pp
Cruise Only£15899pp
21 Rio de Janeiro to Buenos Aires
30 November 2019 - 8 nights

Rio De Janeiro | Rio De Janeiro | Ilhabela | Santos | Montevideo | Punta Del Este | Buenos Aires more

Fly Cruise£2069pp
Cruise Only£979pp
22 Baltra to San Cristobal
30 November 2019 - 7 nights

Baltra, Galapagos, Ecuador | Isla Daphne Grande | Bahia Darwin, Genovesa, Ecuador | El Barranco, Genovesa, Ecuador | Seymour Norte, Ecuador | Santiago (Bahia Sullivan) | Rabida, Ecuador | Santa Cruz (El Eden) | San Cristobal, Ecuador | San Cristobal, Ecuador | Gardner Bay, Española, Ecuador | Punta Suarez, Espanola, Ecuador | Estacion Darwin & Puerto Ayora,Santa Cruz, Ecuado | Plazas Sur, Ecuador | San Cristobal, Ecuador more

Fly Cruise£8439pp
Cruise Only£8439pp
23 South America & Chilean Fjords from Buenos Aires
04 December 2019 - 17 nights

Buenos Aires | Buenos Aires | Montevideo | Puerto Madryn | Port Stanley | Ushuaia, Argentina | Punta Arenas, Chile | Puerto Montt, Chile | Valparaiso, Chile | Valparaiso, Chile more

Fly CruiseCall
Cruise Only£6890pp
24 Ushuaia to Ushuaia
05 December 2019 - 12 nights

Ushuaia, Argentina | Antarctic Peninsula, Antarctica | Antarctic Peninsula, Antarctica | Antarctic Peninsula, Antarctica | Antarctic Peninsula, Antarctica | Antarctic Peninsula, Antarctica | Ushuaia, Argentina more

Fly Cruise£19879pp
Cruise Only£19879pp
25 Chile & Argentina
06 December 2019 - 15 nights

Santiago (San Antonio) | Puerto Montt, Chile | Punta Arenas, Chile | Ushuaia, Argentina | Cape Horn | Puerto Madryn | Punta Del Este | Montevideo | Buenos Aires | Buenos Aires more

Fly Cruise£5279pp
Cruise Only£3159pp
26 Radiant Rhythms
07 December 2019 - 12 nights

Rio De Janeiro | Rio De Janeiro | Buzios | Ilha Grande | Parati | Sao Paulo (Santos) | Porto Belo | Rio Grande | Punta Del Este | Montevideo | Buenos Aires | Buenos Aires more

Fly Cruise£2999pp
Cruise Only£1899pp
27 Buenos Aires to Rio De Janeiro
07 December 2019 - 10 nights

Buenos Aires | Montevideo | Punta Del Este | Rio Grande | Porto Belo | Santos | Parati | Ilha Grande | Buzios | Rio De Janeiro more

Fly Cruise£4849pp
Cruise Only£3229pp
28 Tango, Salsa & Samba Voyage
08 December 2019 - 13 nights

Buenos Aires | Montevideo | Santos | Parati | Buzios | Rio De Janeiro | Rio De Janeiro | Rio De Janeiro | Punta Del Este | Buenos Aires more

Fly Cruise£2599pp
Cruise Only£1379pp
29 Journey along the Pacific Coast
09 December 2019 - 26 nights

Valparaiso, Chile | Valparaiso, Chile | La Serena | Iquique | Arequipa | Pisco (San Martin) | Lima, Peru | Quito (Manta) | Panama City (Fuerte Amador), Panama | Puntarenas, Costa Rica | Puerto Quetzal, Guatemala | Cabo San Lucas, Mexico | San Diego | Los Angeles, California | Los Angeles, California more

Fly Cruise£5190pp
Cruise OnlyCall
30 Rio de Janeiro to Miami
17 December 2019 - 20 nights

Rio De Janeiro | Recife | Alter Do Chao | Boca Da Valeria | Manaus | Manaus | Parintins | Santarem | Castries | Gustavia | Miami, Florida more

Fly Cruise£8649pp
Cruise Only£7589pp
31 Ushuaia to Ushuaia
17 December 2019 - 18 nights

Ushuaia, Argentina | West Point Island, Falkland Islands | Saunders Island | Port Stanley | South Georgia | South Georgia | South Georgia | Elephant Island | Antarctic Peninsula, Antarctica | Antarctic Peninsula, Antarctica | Ushuaia, Argentina more

Fly Cruise£19979pp
Cruise Only£19979pp
32 Holiday Antarctica,Petagonia &South Georgia Island
19 December 2019 - 24 nights

Buenos Aires | Punta Del Este | South Georgia | South Georgia | Antarctic Peninsula, Antarctica | Antarctic Peninsula, Antarctica | Antarctic Peninsula, Antarctica | Antarctic Peninsula, Antarctica | Antarctic Peninsula, Antarctica | Antarctic Peninsula, Antarctica | Ushuaia, Argentina | Punta Arenas, Chile | Gulf Of Corcovado | Castro, Chile | Puerto Montt, Chile | Santiago (San Antonio) more

Fly Cruise£12729pp
Cruise Only£11629pp
33 South America & the Chilean Fjords from Santiago
21 December 2019 - 17 nights

Valparaiso, Chile | Valparaiso, Chile | Puerto Montt, Chile | Punta Arenas, Chile | Ushuaia, Argentina | Port Stanley | Puerto Madryn | Montevideo | Buenos Aires | Buenos Aires more

Fly Cruise£7390pp
Cruise OnlyCall
34 From the Caribbean to the Amazon
21 December 2019 - 21 nights

San Juan | San Juan | Bridgetown | Iles Du Salut, French Guiana | Santarem | Parintins | Manaus, Brazil | Manaus, Brazil | Belem | Scarborough, Tobago | Castries | St. John's, Antigua | St. Thomas | San Juan more

Fly Cruise£5840pp
Cruise OnlyCall
35 New Year's Eve In Rio Voyage
21 December 2019 - 15 nights

Buenos Aires | Montevideo | Montevideo | Santos | Ilhabela | Parati | Buzios | Rio De Janeiro | Rio De Janeiro | Copacabana Beach | Copacabana Beach | Punta Del Este | Buenos Aires more

Fly Cruise£4719pp
Cruise Only£2849pp
36 Miami to Miami
27 December 2019 - 12 nights

Miami, Florida | Key West | Cozumel | Costa Maya | Harvest Caye | Santo Tomas, Guatemala | Roatan Island, Honduras | Puerto Limon | Georgetown (Grand Cayman) | Miami, Florida more

Fly Cruise£6859pp
Cruise Only£6079pp
37 Ushuaia to Ushuaia
04 January 2020 - 15 nights

Ushuaia, Argentina | South Georgia | South Georgia | South Georgia | Elephant Island | Antarctic Peninsula, Antarctica | South Shetland Islands | Ushuaia, Argentina more

Fly Cruise£18799pp
Cruise Only£18799pp
38 South America
05 January 2020 - 14 nights

Santiago (San Antonio) | Puerto Montt, Chile | Punta Arenas, Chile | Ushuaia, Argentina | Cape Horn | Puerto Madryn | Punta Del Este | Montevideo | Buenos Aires | Buenos Aires more

Fly Cruise£7369pp
Cruise Only£6139pp
39 South America & Chilean Fjords from Buenos Aires
07 January 2020 - 17 nights

Buenos Aires | Buenos Aires | Montevideo | Puerto Madryn | Port Stanley | Ushuaia, Argentina | Punta Arenas, Chile | Puerto Montt, Chile | Valparaiso, Chile | Valparaiso, Chile more

Fly Cruise£7540pp
Cruise OnlyCall
40 Ultimate Antarctica & Patagonia
12 January 2020 - 21 nights

Santiago (San Antonio) | Puerto Montt, Chile | Castro, Chile | Punta Arenas, Chile | Ushuaia, Argentina | Antarctic Peninsula, Antarctica | Antarctic Peninsula, Antarctica | Antarctic Peninsula, Antarctica | Antarctic Peninsula, Antarctica | Antarctic Peninsula, Antarctica | Antarctic Peninsula, Antarctica | Port Stanley | Montevideo | Buenos Aires more

Fly Cruise£9049pp
Cruise Only£8479pp
Prices are subject to change and availability. Prices may vary depending on airport selected.

Cruise Lines

By providing your email address and clicking the Submit button, you consent to us sending you cruise holiday deals by email. For further details, please see our Privacy Policy here.

SixStarCruises acts as a retail agent to you and also as a disclosed agent of the holiday provider. Many of the flight inclusive holidays on this website are financially protected by the ATOL scheme. But ATOL protection does not apply to all holiday and travel services listed on this website. Please ask us to confirm what protection may apply to your booking. If you do not receive an ATOL Certificate then the booking will not be ATOL protected. If you do receive an ATOL Certificate but all parts of your trip are not listed on it, those parts will not be ATOL protected. Please see our booking terms and conditions for information or for more information about financial protection and the ATOL Certificate click here
The Foreign & Commonwealth Office have up-to-date advice on staying safe and healthy abroad. Visit the foreign travel advice site for the latest travel updates.
Need help with your next SixStar cruise? Call one of our Concierge, FREE today on 08082026105.
chaticon